Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT
Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
American Society for Microbiology
Abstract
Sequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms that do not confer resistance at a susceptibility breakpoint of 100 μg/ml pyrazinamide in MGIT within a cohort of isolates from South Africa and the U.S. Centers for Disease Control and Prevention.
Description
CITATION: Whitfield, M. G. et al. 2015. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT. Journal of Clinical Microbiology, 53:3633–3635, doi:10.1128/JCM.01001-15.
The original publication is available at http://jcm.asm.org
The original publication is available at http://jcm.asm.org
Keywords
Mycobacterium tuberculosis pncA -- Immunological aspects, Genetic polymorphisms, Pyrazinamide susceptibility, Drug resistance, Sequencing
Citation
Whitfield, M. G. et al. 2015. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT. Journal of Clinical Microbiology, 53:3633–3635, doi:10.1128/JCM.01001-15.