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  • Emergency contraceptive knowledge, attitudes and practices among female students at the University of Botswana : a descriptive survey 

    Kgosiemang, Bobby; Blitz, Julia (AOSIS publishing, 2018-09)
    Background: Unintended pregnancies are associated with unsafe abortions and maternal deaths, particularly in countries such as Botswana, where abortion is illegal. Many of these unwanted pregnancies could be avoided by ...

  • Family medicine training in Africa : views of clinical trainers and trainees 

    Jenkins, Louis S.; Von Pressentin, Klaus (AOSIS publishing, 2018-03)
    Background: This article reports on the findings of a workshop held at the joint 5th World Organisation of Family Doctors (WONCA) Africa and 20th National Family Practitioners Conference in Tshwane, South Africa, in 2017. ...

  • Robustness of rigid and adaptive networks to species loss 

    Nuwagaba, Savannah; Zhang, Feng; Hui, Cang (Public Library of Science, 2017)
    Controversies in the complexity-stability debate have been attributed to the methodologies used such as topological vs. dynamical approaches or rigid vs. adaptive foraging behaviour of species. Here, we use a bipartite ...

  • Prioritising surveillance for alien organisms transported as stowaways on ships travelling to South Africa 

    Faulkner, Katelyn T.; Robertson, Mark P.; Rouget, Mathieu; Wilson, John R. U. (Public Library of Science, 2017)
    The global shipping network facilitates the transportation and introduction of marine and terrestrial organisms to regions where they are not native, and some of these organisms become invasive. South Africa was used as a ...

  • Oncolytic potency and reduced virus tumorspecificity in oncolytic virotherapy. a mathematical modelling approach 

    Mahasa, Khaphetsi Joseph; Eladdadi, Amina; De Pillis, Lisette; Ouifki, Rachid (Public Library of Science, 2017)
    In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal cells in the vicinity of tumor cells enhance oncolytic virotherapy? We formulate ...

  • The burden of mental disorders in the Eastern Mediterranean Region, 1990-2013 

    Charara, Raghid; Forouzanfar, Mohammad; Naghavi, Mohsen; Moradi-Lakeh, Maziar; Afshin, Ashkan; Vos, Theo; Daoud, Farah; Wang, Haidong; El Bcheraoui, Charbel; Khalil, Ibrahim; Hamadeh, Randah R.; Khosravi, Ardeshir; Rahimi-Movaghar, Vafa; Khader, Yousef; Al-Hamad, Nawal; Obermeyer, Carla Makhlouf; Rafay, Anwar; Asghar, Rana; Rana, Saleem M.; Shaheen, Amira; Abu-Rmeileh, Niveen M. E.; Husseini, Abdullatif; Abu-Raddad, Laith J.; Khoja, Tawfik; Al Rayess, Zulfa A.; AlBuhairan, Fadia S.; Hsairi, Mohamed; Alomari, Mahmoud A.; Ali, Raghib; Roshandel, Gholamreza; Terkawi, Abdullah Sulieman; Hamidi, Samer; Refaat, Amany H.; Westerman, Ronny; Kiadaliri, Aliasghar Ahmad; Akanda, Ali S.; Ali, Syed Danish; Bacha, Umar; Badawi, Alaa; Bazargan-Hejazi, Shahrzad; Faghmou, Imad A. D.; Fereshtehnejad, Seyed-Mohammad; Fischer, Florian; Jonas, Jost B.; Defo, Barthelemy Kuate; Mehari, Alem; Omer, Saad B.; Pourmalek, Farshad; Uthman, Olalekan A.; Mokdad, Ali A.; Maalouf, Fadi T.; Abd-Allah, Foad; Akseer, Nadia; Arya, Dinesh; Borschmann, Rohan; Brazinova, Alexandra; Brugha, Traolach S.; Catala-Lopez, Ferran; Degenhardt, Louisa; Ferrari, Alize; Haro, Josep Maria; Horino, Masako; Hornberger, John C.; Huang, Hsiang; Kieling, Christian; Kim, Daniel; Kim, Yunjin; Knudsen, Ann Kristin; Mitchell, Philip B.; Patton, George; Sagar, Rajesh; Satpathy, Maheswar; Savuon, Kim; Seedat, Soraya; Shiue, Ivy; Skogen, Jens Christoffer; Stein, Dan J.; Tabb, Karen M.; Whiteford, Harvey A.; Yip, Paul; Yonemoto, Naohiro; Murray, Christopher J. L.; Mokdad, Ali H. (Public Library of Science, 2017)
    The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental ...

  • Training of workplace-based clinical trainers in family medicine, South Africa : before-and-after evaluation 

    Mash, Robert; Blitz, Julia; Edwards, Jill; Mowle, Steve (AOSIS publishing, 2018-05)
    Background: The training of family physicians is a relatively new phenomenon in the district health services of South Africa. There are concerns about the quality of clinical training and the low pass rate in the national ...

  • Early decreased neutrophil responsiveness is related to late onset sepsis in multitrauma patients : an international cohort study 

    Groeneveld, Kathelijne M.; Koenderman, Leo; Warren, Brian L.; Jol, Saskia; Leenen, Luke P. H.; Hietbrink, Falco (Public Library of Science, 2017)
    Background: Severe trauma can lead to the development of infectious complications after several days, such as sepsis. Early identification of patients at risk will aid anticipating these complications. The aim of this ...

  • Collaborative update of a rule-based expert system for HIV-1 genotypic resistance test interpretation 

    Paredes, Roger; Tzou, Philip L.; Van Zyl, Gert; Barrow, Geoff; Camacho, Ricardo; Carmona, Sergio; Grant, Philip M.; Gupta, Ravindra K.; Hamers, Raph L.; Harrigan, P. Richard; Jordan, Michael R.; Kantor, Rami; Katzenstein, David A.; Kuritzkes, Daniel R.; Maldarelli, Frank; Otelea, Dan; Wallis, Carole L.; Schapiro, Jonathan M.; Shafer, Robert W. (Public Library of Science, 2017)
    Introduction: HIV-1 genotypic resistance test (GRT) interpretation systems (IS) require updates as new studies on HIV-1 drug resistance are published and as treatment guidelines evolve. Methods: An expert panel was ...

  • Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform 

    Theron, A.; Roth, R. L.; Hoppe, H.; Parkinson, C.; Van Der Westhuyzen, C. W.; Stoychev, S.; Wiid, I.; Pietersen, R. D.; Baker, B.; Kenyon, C. P. (Public Library of Science, 2017)
    Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including adenylylation of some or all of the twelve subunits by adenylyl transferase. It ...

  • Child contact management in high tuberculosis burden countries : a mixed-methods systematic review 

    Szkwarko, Daria; Hirsch-Moverman, Yael; Du Plessis, Lienki; Du Preez, Karen; Car, Catherine; Mandalakas, Anna M. (Public Library of Science, 2017)
    s Metrics Comments Media Coverage Abstract Background Materials and methods Results Discussion Conclusions Supporting information References Reader Comments ...

  • Tensile and high cycle fatigue properties of annealed TI6AL4V (ELI) specimens produced by direct metal laser sintering 

    Malefane, Lerata Botsane; Du Preez, W. B.; Maringa, M.; Du Plessis, A. (Southern African Institute for Industrial Engineering, 2018)
    The tensile and high cycle fatigue (HCF) properties of high temperature annealed (HTA) direct metal laser sintered (DMLS) Ti6Al4V extra low interstitial (ELI) machined and polished specimens were investigated. The HTA heat ...

  • A systematic review of the due diligence stage of mergers and acquisitions : towards a conceptual framework 

    Bhagwan, Vivek; Grobbelaar, Sara (Saartjie); Bam, Wouter (Southern African Institute for Industrial Engineering, 2018)
    Organisations are under constant pressure to grow in the face of increased competition, changing conditions, and increasingly relaxed country and currency regulatory environments. In order to remain a player or an idustry ...

  • The megaproject sponsor as leader 

    Louw, Willem; Wium, Jan; Steyn, Herman; Gevers, Wim (Southern African Institute for Industrial Engineering, 2018)
    The importance of the sponsor role, including its contribution to the success or failure of a project, is widely recognised in the project management literature. References to the sponsor’s leadership, and the substantial ...

  • A conceptual framework to increase competitiveness in a biltong factory 

    Henning, Mieke; Hagedorn-Hansen, Devon; Von Leipzig, Konrad H. (Southern African Institute for Industrial Engineering, 2018)
    The global annual biltong market value was estimated at roughly R640 million to R1.1 billion in 2003. By 2015, biltong sales were reported to be more than R2.5 billion. To stay competitive as a biltong manufacturing company ...

  • Developing a challenges landscape relating to drug safety, provision, and distribution in resource-limited settings for the case of HIV/AIDS 

    Huysamen, Biance; De Kock, Imke H.; Bam, Louzanne (Southern African Institute for Industrial Engineering, 2018)
    Since 2010, pharmaceutical organisations have begun to provide drug patents in sub-Saharan Africa through the UN Medicine Patent Pool. This initiative allows any pharmaceutical manufacturer to access these patents and ...

  • Prevalence and factors associated with recent intimate partner violence and relationships between disability and depression in postpartum women in one clinic in eThekwini Municipality, South Africa 

    Gibbs, Andrew; Carpenter, Bradley; Crankshaw, Tamaryn; Hannass-Hancock, Jill; Smit, Jennifer; Tomlinson, Mark; Butler, Lisa (Public Library of Science, 2017)
    Intimate partner violence (IPV) experienced by pregnant and post-partum women has negative health effects for women, as well as the foetus, and the new-born child. In this study we sought to assess the prevalence and factors ...

  • Factors related to environmental barriers experienced by persons with and without disabilities in diverse African settings 

    Visagie, Surona; Eide, Arne H.; Dyrstad, Karin; Mannan, Hasheem; Swartz, Leslie; Schneider, Marguerite; Mji, Gubela; Munthali, Alister; Khogali, Mustafa; Van Rooy, Gert; Hem, Karl-Gerhard; MacLachlan, Malcolm (Public Library of Science, 2017)
    This paper explores differences in experienced environmental barriers between individuals with and without disabilities and the impact of additional factors on experienced environmental barriers. Data was collected in ...

  • Exploring service providers’ perspectives on the prevention and management of fetal alcohol spectrum disorders in South Africa : a qualitative study 

    Adebiyi, Babatope O.; Mukumbang, Ferdinand C.; Cloete, Lizahn G.; Beytell, Anna-Marie (BMC (part of Springer Nature), 2018-11-06)
    Background: Fetal alcohol spectrum disorder (FASD) is among the leading causes of developmental and intellectual disabilities in individuals. Although efforts are being made toward the prevention and management of FASD ...

  • Pilot production environments driven by digital twins 

    Lutters, E. (Southern African Institute for Industrial Engineering, 2018)
    Establishing production environments requires joint decision-making by stakeholders from many disciplines at different levels of aggregation, because of the significant, unpredictable, and risky investments involved. Pilot ...

  • Development of a discrete-event, stochastic multi-objective metaheuristic simulation optimisation suite for a commercial software package 

    Bamporiki, Toussaint Victor; Bekker, James (Southern African Institute for Industrial Engineering, 2018)
    In this paper, the authors present the development of an optimisation suite and its implementation. This paper is part of an ongoing project that aims at developing a hybrid metaheuristic optimisation suite to solve ...

  • Beyond funding : acknowledgement patterns in biomedical, natural and social sciences 

    Paul-Hus, Adele; Diaz-Faes, Adrian A.; Sainte-Marie, Maxime; Desrochers, Nadine; Costas, Rodrigo; Lariviere, Vincent (Public Library of Science, 2017)
    For the past 50 years, acknowledgments have been studied as important paratextual traces of research practices, collaboration, and infrastructure in science. Since 2008, funding acknowledgments have been indexed by Web ...

  • Host-seeking efficiency can explain population dynamics of the tsetse fly Glossina morsitans morsitans in response to host density decline 

    Lord, Jennifer S.; Mthombothi, Zinhle; Lagat, Vitalis K.; Atuhaire, Fatumah; Hargrove, John W. (Public Library of Science, 2017)
    Females of all blood-feeding arthropod vectors must find and feed on a host in order to produce offspring. For tsetse—vectors of the trypanosomes that cause human and animal African trypanosomiasis—the problem is more ...

  • A dynamic model for estimating adult female mortality from ovarian dissection data for the tsetse fly Glossina pallidipes Austen sampled in Zimbabwe 

    Ackley, Sarah F.; Hargrove, John W. (Public Library of Science, 2017)
    Human and animal trypanosomiasis, spread by tsetse flies (Glossina spp), is a major public health concern in much of sub-Saharan Africa. The basic reproduction number of vector-borne diseases, such as trypanosomiasis, is ...

  • Hepatitis B virus infection as a neglected tropical disease 

    O'Hara, Geraldine A.; McNaughton, Anna L.; Maponga, Tongai; Jooste, Pieter; Ocama, Ponsiano; Chileng, Roma; Mokaya, Jolynne; Liyayi, Mitchell I.; Wachira, Tabitha; Gikungi, David M.; Burbridge, Lela; O'Donnel, Denise; Akiror, Connie S.; Sloan, Derek; Torimiro, Judith; Yindom, Louis Marie; Walton, Robert; Andersson, Monique; Marsh, Kevin; Newton, Robert; Matthews, Philippa C. (Public Library of Science, 2017)
    The Global Hepatitis Health Sector Strategy is aiming for “elimination of viral hepatitis as a public health threat” by 2030 [1], while enhanced elimination efforts for hepatitis are also promoted under the broader remit ...

  • Vacuum polarization energy for general backgrounds in one space dimension 

    Weigel, H. (Elsevier, 2017)
    For field theories in one time and one space dimensions we propose an efficient method to compute the vacuum polarization energy of static field configurations that do not allow a decomposition into symmetric and anti-symmetric ...

  • Consistency between SU(3) and SU(2) covariant baryon chiral perturbation theory for the nucleon mass 

    Ren, Xiu-Lei; Alvarez-Ruso, L.; Geng, Li-Sheng; Ledwig, Tim; Meng, Jie; Vacas, M. J. Vicente (Elsevier, 2017)
    Treating the strange quark mass as a heavy scale compared to the light quark mass, we perform a matching of the nucleon mass in the SU(3) sector to the two-flavor case in covariant baryon chiral perturbation theory. The ...

  • Superfluid filaments of dipolar bosons in free space 

    Cinti, Fabio; Cappellaro, Alberto; Salasnich, Luca; Macri, Tommaso (American Physical Society, 2017)
    We systematically investigate the zero temperature phase diagram of bosons interacting via dipolar interactions in three dimensions in free space via path integral Monte Carlo simulations with a few hundreds of particles ...

  • Identifiers for the 21st century : how to design, provision, and reuse persistent identifiers to maximize utility and impact of life science data 

    McMurry, Julie A.; Juty, Nick; Blomberg, Niklas; Burdett, Tony; Conlin, Tom; Conte, Nathalie; Courtot, Melanie; Deck, John; Dumontier, Michel; Fellows, Donal K.; Gonzalez-Beltran, Alejandra; Gormanns, Philipp; Grethe, Jeffrey; Hastings, Janna; Heriche, Jean-Karim; Hermjakob, Henning; Ison, Jon C.; Jimenez, Rafael C.; Jupp, Simon; Kunze, John; Laibe, Camille; Le Novere, Nicolas; Malone, James; Martin, Maria Jesus; McEntyre, Johanna R.; Morris, Chris; Muilu, Juha; Muller, Wolfgang; Rocca-Serra, Philippe; Sansone, Susanna-Assunta; Sariyar, Murat; Snoep, Jacky L.; Soiland-Reyes, Stian; Stanford, Natalie J.; Swainston, Neil; Washington, Nicole; Williams, Alan R.; Wimalaratne, Sarala M.; Winfree, Lilly M.; Wolstencroft, Katherine; Goble, Carole; Mungall, Christopher J.; Haende, Melissa A.; Parkinson, Helen (Public Library of Science, 2017)
    In many disciplines, data are highly decentralized across thousands of online databases (repositories, registries, and knowledgebases). Wringing value from such databases depends on the discipline of data science and on ...

  • Thermal decomposition analysis in a sphere of combustible materials 

    Lebelo, Ramoshweu Solomon; Makinde, Oluwole Daniel; Chinyoka, T. (Sage, 2017)
    In this article, we look at spontaneous combustion due to exothermic chemical reaction taking place within a stockpile of combustible material. The model includes mass and energy balance equations in a spherical domain. ...

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