Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT

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dc.contributor.authorWhitfield, Michael G.en_ZA
dc.contributor.authorWarren, Robin M.en_ZA
dc.contributor.authorStreicher, Elizabeth M.en_ZA
dc.contributor.authorSampson, Samantha L.en_ZA
dc.contributor.authorSirgel, Frik A.en_ZA
dc.contributor.authorVan Helden, Paul D.en_ZA
dc.contributor.authorMercante, Alexandraen_ZA
dc.contributor.authorWillby, Melisaen_ZA
dc.contributor.authorHughes, Kelseyen_ZA
dc.contributor.authorBirkness, Krisen_ZA
dc.contributor.authorMorlock, Glenmen_ZA
dc.contributor.authorVan Rie, Anneliesen_ZA
dc.contributor.authorPosey, James E.en_ZA
dc.date.accessioned2016-10-06T07:23:57Z
dc.date.available2016-10-06T07:23:57Z
dc.date.issued2015
dc.descriptionCITATION: Whitfield, M. G. et al. 2015. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT. Journal of Clinical Microbiology, 53:3633–3635, doi:10.1128/JCM.01001-15.
dc.descriptionThe original publication is available at http://jcm.asm.org
dc.description.abstractSequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms that do not confer resistance at a susceptibility breakpoint of 100 μg/ml pyrazinamide in MGIT within a cohort of isolates from South Africa and the U.S. Centers for Disease Control and Prevention.en_ZA
dc.description.urihttp://jcm.asm.org/content/53/11/3633.abstract?sid=13f06819-4c59-4a74-b9d4-420336a00b30
dc.description.versionPublisher's version
dc.format.extent3 pages
dc.identifier.citationWhitfield, M. G. et al. 2015. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT. Journal of Clinical Microbiology, 53:3633–3635, doi:10.1128/JCM.01001-15.
dc.identifier.issn1098-660X (online)
dc.identifier.issn0095-1137 (print)
dc.identifier.otherdoi:10.1128/JCM.01001-15
dc.identifier.urihttp://hdl.handle.net/10019.1/99699
dc.language.isoen_ZAen_ZA
dc.publisherAmerican Society for Microbiology
dc.rights.holderAmerican Society for Microbiology
dc.subjectMycobacterium tuberculosis pncA -- Immunological aspectsen_ZA
dc.subjectGenetic polymorphismsen_ZA
dc.subjectPyrazinamide susceptibilityen_ZA
dc.subjectDrug resistanceen_ZA
dc.subjectSequencingen_ZA
dc.titleMycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGITen_ZA
dc.typeArticleen_ZA
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