Browsing by Author "Willby, Melisa"
Now showing 1 - 1 of 1
Results Per Page
- ItemMycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 micrograms per milliliter in MGIT(American Society for Microbiology, 2015) Whitfield, Michael G.; Warren, Robin M.; Streicher, Elizabeth M.; Sampson, Samantha L.; Sirgel, Frik A.; Van Helden, Paul D.; Mercante, Alexandra; Willby, Melisa; Hughes, Kelsey; Birkness, Kris; Morlock, Glenm; Van Rie, Annelies; Posey, James E.Sequencing of the Mycobacterium tuberculosis pncA gene allows for pyrazinamide susceptibility testing. We summarize data on pncA polymorphisms that do not confer resistance at a susceptibility breakpoint of 100 μg/ml pyrazinamide in MGIT within a cohort of isolates from South Africa and the U.S. Centers for Disease Control and Prevention.