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Epidemiology of major depressive disorder in South Africa (1997 – 2015): a systematic review protocol

dc.contributor.authorNglazi, Mweete D.en_ZA
dc.contributor.authorJoubert, Jane D.en_ZA
dc.contributor.authorStein, Dan J.en_ZA
dc.contributor.authorLund, Cricken_ZA
dc.contributor.authorWiysonge, Charles S.en_ZA
dc.contributor.authorVos, Theoen_ZA
dc.contributor.authorPillay-van Wyk, Victoriaen_ZA
dc.contributor.authorRoomaney, Rifqah A.en_ZA
dc.contributor.authorMuhwava, Lorrein S.en_ZA
dc.contributor.authorBradshaw, Debbieen_ZA
dc.date.accessioned2017-08-03T12:15:55Z
dc.date.available2017-08-03T12:15:55Z
dc.date.issued2016
dc.identifier.citationNglazi, M. D., et al. 2016. Epidemiology of major depressive disorder in South Africa (1997 – 2015) : a systematic review protocol. BMJ Open, 6:e011749, doi:10.1136/bmjopen-2016- 011749
dc.identifier.issn2044-6055 (online)
dc.identifier.otherdoi:10.1136/bmjopen-2016-
dc.identifier.urihttp://hdl.handle.net/10019.1/102044
dc.descriptionCITATION: Nglazi, M. D., et al. 2016. Epidemiology of major depressive disorder in South Africa (1997 – 2015) : a systematic review protocol. BMJ Open, 6:e011749, doi:10.1136/bmjopen-2016-
dc.descriptionThe original publication is available at http://bmjopen.bmj.com
dc.description.abstractENGLISH SUMMARY : Introduction: Major depressive disorder (MDD) is a leading cause of disease and disability globally and in South Africa. Epidemiological data for MDD are essential to estimate the overall disease burden in a country. The objective of the systematic review is to examine the evidence base for prevalence, incidence, remission, duration, severity, case fatality and excess mortality of MDD in South Africa from 1997 to 2015. Methods and analysis: We will perform electronic searches in PubMed, PsycINFO, Scopus and other bibliographical databases. Articles published between January 1997 and December 2015 will be eligible for inclusion in this review. The primary outcomes will be prevalence, incidence, remission, duration, severity, case fatality and excess mortality of MDD. The secondary outcomes will be risk factors and selected populations for MDD. If appropriate, a meta-analysis will be performed. If a meta-analysis is not possible, the review findings will be presented narratively and in tables. Subgroup analyses will be conducted with subgroups defined by population group, rural/urban settings and study designs, if sufficient data are available.en_ZA
dc.description.urihttp://bmjopen.bmj.com/content/6/7/e011749.info
dc.format.extent7 pages
dc.language.isoen_ZAen_ZA
dc.publisherBMJ Publishing Group
dc.subjectMajor depressive disorderen_ZA
dc.subjectDepression, Mental -- Epidemiology -- South Africaen_ZA
dc.subjectSystematic reviews (Medical research)en_ZA
dc.titleEpidemiology of major depressive disorder in South Africa (1997 – 2015): a systematic review protocolen_ZA
dc.typeArticleen_ZA
dc.description.versionPublisher's version
dc.rights.holderAuthors retain copyright


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