Acute extrapyramidal dysfunction in two HIV-infected children

Simple item page
dc.contributor.authorSolomons R.
dc.contributor.authorSlogrove, Amy L.en_ZA
dc.contributor.authorSchoeman J.
dc.contributor.authorMarais B.
dc.contributor.authorvan Zyl G.
dc.contributor.authorMaritz J.
dc.contributor.authorvan Toorn R.
dc.date.accessioned2011-10-13T16:58:14Z
dc.date.available2011-10-13T16:58:14Z
dc.date.issued2011
dc.description.abstractInvolvement of the basal ganglia is well documented in children with human immunodeficiency virus (HIV) encephalopathy, often with calcification. High concentrations of HIV protein have been detected in affected basal ganglia, although extrapyramidal dysfunction, in contrast to adults, is infrequently encountered in HIV-infected children. We describe the clinical course, magnetic resonance imaging appearance and outcome of two HIV-infected children who presented with acute debilitating extrapyramidal dysfunction. The cases highlight the importance of immune competence, co-existence of opportunistic infections, HIV testing of all children of HIV-infected mothers and magnetic resonance imaging when assessing the severity and anticipating outcomes of movement disorders in HIV-infected children. © The Author [2010]. Published by Oxford University Press. All rights reserved.
dc.description.versionArticle
dc.identifier.citationJournal of Tropical Pediatrics
dc.identifier.citation57
dc.identifier.citation3
dc.identifier.citationhttp://www.scopus.com/inward/record.url?eid=2-s2.0-79957854890&partnerID=40&md5=d2523ad606dccba2746fe7b19bf55d3d
dc.identifier.issn1426338
dc.identifier.other10.1093/tropej/fmq080
dc.identifier.urihttp://hdl.handle.net/10019.1/16657
dc.subjectCytomegalovirus encephaliti
dc.subjectHuman immunodeficiency virus
dc.subjectMovement disorders
dc.subjectcarbidopa plus levodopa
dc.subjectefavirenz
dc.subjectlamivudine
dc.subjectzidovudine
dc.subjectarticle
dc.subjectcase report
dc.subjectchild
dc.subjectclinical feature
dc.subjectdisease association
dc.subjectdisease severity
dc.subjectevening dosage
dc.subjectextrapyramidal syndrome
dc.subjectfemale
dc.subjecthighly active antiretroviral therapy
dc.subjecthuman
dc.subjectHuman immunodeficiency virus infection
dc.subjectimmunocompetence
dc.subjectlaboratory test
dc.subjectmale
dc.subjectmorning dosage
dc.subjectneurologic examination
dc.subjectnuclear magnetic resonance imaging
dc.subjectopportunistic infection
dc.subjectpreschool child
dc.subjectschool child
dc.subjecttreatment response
dc.titleAcute extrapyramidal dysfunction in two HIV-infected children
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Publications