Spoligotype signatures in the Mycobacterium tuberculosis complex

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dc.contributor.authorStreicher E.M.
dc.contributor.authorVictor T.C.
dc.contributor.authorVan Der Spuy G.
dc.contributor.authorSola C.
dc.contributor.authorRastogi N.
dc.contributor.authorVan Helden P.D.
dc.contributor.authorWarren R.M.
dc.date.accessioned2011-05-15T15:56:55Z
dc.date.available2011-05-15T15:56:55Z
dc.date.issued2007
dc.description.abstractEvolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine trials. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
dc.description.versionArticle
dc.identifier.citationJournal of Clinical Microbiology
dc.identifier.citation45
dc.identifier.citation1
dc.identifier.issn951137
dc.identifier.other10.1128/JCM.01429-06
dc.identifier.urihttp://hdl.handle.net/10019.1/10114
dc.subjectantibiotic resistance
dc.subjectarticle
dc.subjectbacterial strain
dc.subjectDNA fingerprinting
dc.subjectevolution
dc.subjectgenotype
dc.subjectimmunity
dc.subjectMycobacterium tuberculosis
dc.subjectnonhuman
dc.subjectpopulation structure
dc.subjectpriority journal
dc.subjectsingle nucleotide polymorphism
dc.subjectSouth Africa
dc.subjectspoligotype
dc.subjectBacterial Typing Techniques
dc.subjectDNA Transposable Elements
dc.subjectEvolution, Molecular
dc.subjectGenotype
dc.subjectHumans
dc.subjectMycobacterium tuberculosis
dc.subjectOligonucleotides
dc.subjectRepetitive Sequences, Nucleic Acid
dc.subjectMycobacterium tuberculosis
dc.subjectMycobacterium tuberculosis complex
dc.titleSpoligotype signatures in the Mycobacterium tuberculosis complex
dc.typeArticle
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