Spoligotype signatures in the Mycobacterium tuberculosis complex
Date
2007
Authors
Streicher E.M.
Victor T.C.
Van Der Spuy G.
Sola C.
Rastogi N.
Van Helden P.D.
Warren R.M.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Evolution of the direct repeat region in Mycobacterium tuberculosis has created unique spoligotype signatures specifically associated with IS6110-defined strain families. Spoligotyping signatures may enable the analysis of the strain population structure in different settings and will enable the rapid identification of strain families that acquire drug resistance or escape protective immunity in drug and vaccine trials. Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Description
Keywords
antibiotic resistance, article, bacterial strain, DNA fingerprinting, evolution, genotype, immunity, Mycobacterium tuberculosis, nonhuman, population structure, priority journal, single nucleotide polymorphism, South Africa, spoligotype, Bacterial Typing Techniques, DNA Transposable Elements, Evolution, Molecular, Genotype, Humans, Mycobacterium tuberculosis, Oligonucleotides, Repetitive Sequences, Nucleic Acid, Mycobacterium tuberculosis, Mycobacterium tuberculosis complex
Citation
Journal of Clinical Microbiology
45
1
45
1