Human whole genome sequencing in South Africa
Date
2021-01
Journal Title
Journal ISSN
Volume Title
Publisher
Nature
Abstract
The advent and evolution of next generation sequencing has considerably impacted genomic research. Until recently, South African researchers were unable to access affordable platforms capable of human whole genome sequencing locally and DNA samples had to be exported. Here we report the whole genome sequences of the first six human DNA samples sequenced and analysed at the South African Medical Research Council’s Genomics Centre. We demonstrate that the data obtained is of high quality, with an average sequencing depth of 36.41, and that the output is comparable to data generated internationally on a similar platform. The Genomics Centre creates an environment where African researchers are able to access world class facilities, increasing local capacity to sequence whole genomes as well as store and analyse the data.
Description
CITATION: Glanzmann, B. et al. 2021. Human whole genome sequencing in South Africa. Scientific Reports, 11:606, doi:10.1038/s41598-020-79794-x.
The original publication is available at https://www.nature.com
The original publication is available at https://www.nature.com
Keywords
Nucleotide sequence -- South Africa, Human genome -- South Africa, High-throughput nucleotide sequencing
Citation
Glanzmann, B. et al. 2021. Human whole genome sequencing in South Africa. Scientific Reports, 11:606, doi:10.1038/s41598-020-79794-x.