Doctoral Degrees (Chemical Pathology)
Recent Submissions
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Investigation of the role of vitamin D metabolism in South African breast cancer patients using a pathology-supported genetic testing platform
(Stellenbosch : Stellenbosch University., 2020-03)ENGLISH ABSTRACT: The high global breast cancer incidence drives the development of novel genomic approaches for disease prevention and targeted treatment. Towards this goal, a pathology-supported genetic testing (PSGT) ... -
Methodological issues around the validation of models for predicting diabetes risk in developing countries
(Stellenbosch : Stellenbosh University, 2016-12)ENGLISH SUMMARY: Background: Multivariable diabetes risk prediction models have the potential to contribute to screening strategies, combining several risk factors to predict undiagnosed diabetes or future risk of developing ... -
HbA1c as a screening tool for diabetes mellitus and its use with traditional and novel biochemical parameters to predict cardiovascular risk in a local urban community
(Stellenbosch : Stellenbosh University, 2016-12)ENGLISH SUMMARY: Introduction The global obesity pandemic has reached Africa and the diabetes mellitus (DM) prevalence is increasing in parallel. A high prevalence of DM and risk for cardiovascular disease (CVD) has ... -
Molecular investigation of genetic factors associated with insulin resistance and obesity in a South African population
(Stellenbosch : Stellenbosh University, 2015-12)ENGLISH ABSTRACT: Background: The aetiopathogenesis of type 2 diabetes and the associated insulin resistance have been shown to have a strong genetic basis. Several genetic variants of the peroxisome proliferatoractivat ... -
Molecular investigation of genetic and environmental factors contributing to obesity in adolescent learners residing in the semi-urban/rural areas of the Western Cape Province, South Africa
(Stellenbosch : Stellenbosch University, 2012-12)ENGLISH ABSTRACT: Background/Aims: Obesity has increased rapidly in South African children and adolescents with significant variability observed among racial groups. Genes that regulate appetite have been studied in different ... -
Interactions between the noradrenergic and dopaminergic neurotransmitter systems in the rat brain
(Stellenbosch : Stellenbosch University, 1990)ENGLISH ABSTRACT: The development of a dissection technique enabled the nucleus accumbens to be dissected into six and the striatum into eighteen discrete areas. The concentration of monoamines in these areas was analysed ... -
Mutational analysis of the solute carrier family 11 member 1 gene (SLC11A1) implicated in iron transport
(Stellenbosch : Stellenbosch University, 2003-12)ENGLISH ABSTRACT: The solute carrier family 11 member 1 gene (SLC11A 1) is a divalent metal ion transporter with various pleiotropic effects on macrophage function. This gene that regulates iron, and is also regulated ...
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