Validity of the K-10 in detecting DSM-IV-defined depression and anxiety disorders among HIV-infected individuals
Date
2009
Authors
Spies G.
Kader K.
Kidd M.
Smit J.
Myer L.
Stein D.J.
Seedat S.
Journal Title
Journal ISSN
Volume Title
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Abstract
It has been suggested that an HIV diagnosis may increase the likelihood of mental disorders among infected individuals and that the progression of HIV may be hastened by mental disorders like anxiety and depression. Therefore, a brief screening measure, with good sensitivity/specificity for psychiatric diagnoses that could be given to HIV-infected individuals would be useful. We assessed the validity of the K-10, using the MINI International Neuropsychiatric Interview as the gold standard, in a sample of 429 HIV-infected adults enrolled in HIV care and treatment services near Cape Town, South Africa. There was significant agreement between the K-10 and the MINI-defined depressive and anxiety disorders. A receiver operating characteristic (ROC) curve analysis indicated that the K-10 showed agreeable sensitivity and specificity in detecting depression (area under the ROC curve, 0.77), generalized anxiety disorder (0.78), and posttraumatic stress disorder (PTSD) (0.77). The K-10 may be a useful screening measure for detecting mood and anxiety disorders, including PTSD, in patients with HIV/AIDS.
Description
Keywords
acquired immune deficiency syndrome, adult, aged, agoraphobia, area under the curve, article, clinical assessment, controlled study, depression, diagnostic accuracy, diagnostic and statistical manual of mental disorders, diagnostic value, female, generalized anxiety disorder, gold standard, health care, health service, human, Human immunodeficiency virus, Human immunodeficiency virus infected patient, Human immunodeficiency virus infection, interview, major clinical study, male, mood disorder, neuropsychiatry, panic, posttraumatic stress disorder, priority journal, psychological rating scale, receiver operating characteristic, sample, screening, social phobia, South Africa, validity, Adult, Anxiety Disorders, Brief Psychiatric Rating Scale, Depressive Disorder, Female, HIV Infections, Humans, Male, ROC Curve, Sensitivity and Specificity
Citation
AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
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