Validity of the K-10 in detecting DSM-IV-defined depression and anxiety disorders among HIV-infected individuals

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dc.contributor.authorSpies G.
dc.contributor.authorKader K.
dc.contributor.authorKidd M.
dc.contributor.authorSmit J.
dc.contributor.authorMyer L.
dc.contributor.authorStein D.J.
dc.contributor.authorSeedat S.
dc.date.accessioned2011-05-15T15:58:48Z
dc.date.available2011-05-15T15:58:48Z
dc.date.issued2009
dc.description.abstractIt has been suggested that an HIV diagnosis may increase the likelihood of mental disorders among infected individuals and that the progression of HIV may be hastened by mental disorders like anxiety and depression. Therefore, a brief screening measure, with good sensitivity/specificity for psychiatric diagnoses that could be given to HIV-infected individuals would be useful. We assessed the validity of the K-10, using the MINI International Neuropsychiatric Interview as the gold standard, in a sample of 429 HIV-infected adults enrolled in HIV care and treatment services near Cape Town, South Africa. There was significant agreement between the K-10 and the MINI-defined depressive and anxiety disorders. A receiver operating characteristic (ROC) curve analysis indicated that the K-10 showed agreeable sensitivity and specificity in detecting depression (area under the ROC curve, 0.77), generalized anxiety disorder (0.78), and posttraumatic stress disorder (PTSD) (0.77). The K-10 may be a useful screening measure for detecting mood and anxiety disorders, including PTSD, in patients with HIV/AIDS.
dc.description.versionArticle
dc.identifier.citationAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
dc.identifier.citation21
dc.identifier.citation9
dc.identifier.issn9540121
dc.identifier.other10.1080/09540120902729965
dc.identifier.urihttp://hdl.handle.net/10019.1/10858
dc.subjectacquired immune deficiency syndrome
dc.subjectadult
dc.subjectaged
dc.subjectagoraphobia
dc.subjectarea under the curve
dc.subjectarticle
dc.subjectclinical assessment
dc.subjectcontrolled study
dc.subjectdepression
dc.subjectdiagnostic accuracy
dc.subjectdiagnostic and statistical manual of mental disorders
dc.subjectdiagnostic value
dc.subjectfemale
dc.subjectgeneralized anxiety disorder
dc.subjectgold standard
dc.subjecthealth care
dc.subjecthealth service
dc.subjecthuman
dc.subjectHuman immunodeficiency virus
dc.subjectHuman immunodeficiency virus infected patient
dc.subjectHuman immunodeficiency virus infection
dc.subjectinterview
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmood disorder
dc.subjectneuropsychiatry
dc.subjectpanic
dc.subjectposttraumatic stress disorder
dc.subjectpriority journal
dc.subjectpsychological rating scale
dc.subjectreceiver operating characteristic
dc.subjectsample
dc.subjectscreening
dc.subjectsocial phobia
dc.subjectSouth Africa
dc.subjectvalidity
dc.subjectAdult
dc.subjectAnxiety Disorders
dc.subjectBrief Psychiatric Rating Scale
dc.subjectDepressive Disorder
dc.subjectFemale
dc.subjectHIV Infections
dc.subjectHumans
dc.subjectMale
dc.subjectROC Curve
dc.subjectSensitivity and Specificity
dc.titleValidity of the K-10 in detecting DSM-IV-defined depression and anxiety disorders among HIV-infected individuals
dc.typeArticle
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