Research Articles (Health Systems and Public Health)
Recent Submissions
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The 17th International Congress on Infectious Diseases workshop on developing infection prevention and control resources for low - and middle-income countries
(Published by Elsevier on behalf of International Society for Infectious Diseases, 2017)Hospital-acquired infections (HAIs) are a major concern to healthcare systems around the world. They are associated with significant morbidity and mortality, in addition to increased hospitalization costs. Recent outbreaks, ... -
Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
(Cochrane, 2014)Background: Kaposi’s sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy ... -
Maternal colonization or infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae in Africa : a systematic review and meta-analysis
(Published by Elsevier on behalf of International Society for Infectious Diseases, 2017)Objective: To summarize published studies on the prevalence of and risk factors for maternal bacterial colonization and/or infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) in pregnant ... -
Cost of illness for outpatients attending public and private hospitals in Bangladesh
(BMC (part of Springer Nature), 2016)Background: A central aim of Universal Health Coverage (UHC) is protection for all against the cost of illness. In a low income country like Bangladesh the cost burden of health care in tertiary facilities is likely to be ... -
Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)
(BioMed Central, 2018-04-10)Background: Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root ... -
Research protocol : Cisplatin-associated ototoxicity amongst patients receiving cancer chemotherapy and the feasibility of an audiological monitoring program
(BioMed Central, 2017-12-11)Abstract Background Cisplatin is an anti-cancer chemotherapy drug classified as an alkylating agent. It is used for the treatment of a variety of cancers such as cervical, ... -
Perceptions about data-informed decisions : an assessment of information-use in high HIV-prevalence settings in South Africa
(BioMed Central, 2017-12-04)Background: Information-use is an integral component of a routine health information system and essential to influence policy-making, program actions and research. Despite an increased amount of routine data collected, ... -
Multiple and mixed methods in formative evaluation : is more better? reflections from a South African study
(BioMed Central, 2016)ENGLISH SUMMARY : Background: Formative programme evaluations assess intervention implementation processes, and are seen widely as a way of unlocking the 'black box' of any programme in order to explore and understand ... -
Researching complex interventions in health : the state of the art
(BMC Health Services Research, 2016)ENGLISH SUMMARY : Keynote presentations -
A partial economic evaluation of blended learning in teaching health research methods : a three-university collaboration in South Africa, Sweden, and Uganda
(Taylor & Francis Open, 2016)ENGLISH SUMMARY : Background: Novel research training approaches are needed in global health, particularly in sub-Saharan African universities, to support strengthening of health systems and services. Blended learning (BL), ... -
Student experiences of participating in five collaborative blended learning courses in Africa and Asia : a survey
(Taylor & Francis Open, 2016)ENGLISH SUMMARY : Background: As blended learning (BL; a combination of face-to-face and e-learning methods) becomes more commonplace, it is important to assess whether students find it useful for their studies. ARCADE ... -
Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)
(BioMed Central, 2017-08-01)Background: Cancer cachexia is associated with increased pro-inflammatory cytokine levels. Centella asiatica (C. asiatica) possesses antioxidant, anti-inflammatory and anti-tumour potential. We investigated the modulation ... -
Health-seeking behaviours of older black women living with non-communicable diseases in an urban township in South Africa
(BioMed Central, 2016)Background: Various studies have shown that non-communicable diseases (NCDs) especially diabetes and hypertension are prevalent among older women living in South African urban areas, placing a heavy burden on the healthcare ... -
A systematic review of economic evaluations of CHW interventions aimed at improving child health outcomes
(BioMed Central, 2017-02-28)ENGLISH SUMMARY : Evidence of the cost-effectiveness of community health worker interventions is pertinent for decision-makers and programme planners who are turning to community services in order to strengthen health ... -
Are central hospitals ready for national health insurance? ICD coding quality from an electronic patient discharge record for clinicians
(Health & Medical Publishing Group, 2016-02)ENGLISH SUMMARY : Background. South Africa (SA)’s planned National Health Insurance reforms require the use of International Statistical Classification of Diseases (ICD) codes for hospitals to purchase services from the ... -
An overview of cancer research in South African academic and research institutions, 2013 - 2014
(Health & Medical Publishing Group, 2016-06)ENGLISH SUMMARY : Background and objectives. Cancer is emerging as a critical public health problem in South Africa (SA). Recognising the importance of research in addressing the cancer burden, the Ministerial Advisory ... -
The challenges of reshaping disease specific and care oriented community based services towards comprehensive goals : a situation appraisal in the Western Cape Province, South Africa
(BioMed Central, 2015-09-30)ENGLISH SUMMARY : Background: Similar to other countries in the region, South Africa is currently reorienting a loosely structured and highly diverse community care system that evolved around HIV and TB, into a formalized, ... -
The impact of mass media interventions on tuberculosis awareness, health-seeking behaviour and health service utilisation : a systematic review protocol
(BMJ Publishing Group, 2014-12)Introduction: Tuberculosis (TB) is a serious public health problem in many parts of the world. Strategies to curb the spread of TB must match the multifaceted nature of the epidemic. The use of mass media is one of the ... -
Protocol for a systematic review of the effects of interventions to inform or educate caregivers about childhood vaccination in low and middle-income countries
(BMJ Publishing Group, 2015)ENGLISH SUMMARY : Introduction: Despite their proven effectiveness in reducing childhood infectious diseases, the uptake of vaccines remains suboptimal in low and middle-income countries. Identifying strategies for ... -
Electronic and postal reminders for improving immunisation coverage in children : protocol for a systematic review and meta-analysis
(BMJ Publishing Group, 2015)ENGLISH SUMMARY : Introduction: Worldwide, suboptimal immunisation coverage causes the deaths of more than one million children under five from vaccine-preventable diseases every year. Reasons for suboptimal coverage are ...
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