Research Articles (Health Systems and Public Health)
Recent Submissions
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Please don’t send us spam! a participative, theory-based methodology for developing an mHealth intervention
(JMIR Publications, 2017)Background: Mobile health solutions have the potential of reducing burdens on health systems and empowering patients with important information. However, there is a lack of theory-based mHealth interventions. Objective: ... -
Protocol for a systematic review of the effects of interventions for vaccine stock management
(BMC (part of Springer Nature), 2019-01-08)Background: Inadequate vaccine stock management in health facilities leads to vaccine stock-outs. The latter threatens the success of immunisation programmes. Countries have used various approaches to reduce stock-outs ... -
Desalination and seawater quality at Green Point, Cape Town : a study on the effects of marine sewage outfalls
(Academy of Science of South Africa, 2017)This paper presents our collection methods, laboratory protocols and findings in respect of sewage pollution affecting seawater and marine organisms in Table Bay, Cape Town, South Africa, then moves to consider ... -
When students become patients : TB disease among medical undergraduates in Cape Town, South Africa
(Health & Medical Publishing Group, 2017)Background. Medical students acquire latent tuberculosis (TB) infection at a rate of 23 cases/100 person-years. The frequency and impact of occupational TB disease in this population are unknown. Methods. A self-administered ... -
Pandemic influenza preparedness in the WHO African region : are we ready yet?
(BMC (part of Springer Nature), 2018)Background: Prior to the 2009 pandemic H1N1, and the unprecedented outbreak of Highly Pathogenic Avian Influenza (HPAI) caused by the H5N1 virus, the World Health Organization (WHO) called upon its Member States to develop ... -
The 17th International Congress on Infectious Diseases workshop on developing infection prevention and control resources for low - and middle-income countries
(Published by Elsevier on behalf of International Society for Infectious Diseases, 2017)Hospital-acquired infections (HAIs) are a major concern to healthcare systems around the world. They are associated with significant morbidity and mortality, in addition to increased hospitalization costs. Recent outbreaks, ... -
Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
(Cochrane, 2014)Background: Kaposi’s sarcoma remains the most common cancer in Sub-Saharan Africa and the second most common cancer in HIV-infected patients worldwide. Since the introduction of highly active antiretroviral therapy ... -
Maternal colonization or infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae in Africa : a systematic review and meta-analysis
(Published by Elsevier on behalf of International Society for Infectious Diseases, 2017)Objective: To summarize published studies on the prevalence of and risk factors for maternal bacterial colonization and/or infection with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) in pregnant ... -
Cost of illness for outpatients attending public and private hospitals in Bangladesh
(BMC (part of Springer Nature), 2016)Background: A central aim of Universal Health Coverage (UHC) is protection for all against the cost of illness. In a low income country like Bangladesh the cost burden of health care in tertiary facilities is likely to be ... -
Modelling the cost of community interventions to reduce child mortality in South Africa using the Lives Saved Tool (LiST)
(BMJ Publishing Group, 2017-08)Objective: To estimate the costs and impact on reducing child mortality of scaling up interventions that can be delivered by community health workers at community level from a provider’s perspective. Setting: In this ... -
Withania somnifera modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)
(BioMed Central, 2018-04-10)Background: Cancer and inflammation are associated with cachexia. Withania somnifera (W. somnifera) possesses antioxidant and anti-inflammatory potential. We investigated the potential of an aqueous extract of the root ... -
Research protocol : Cisplatin-associated ototoxicity amongst patients receiving cancer chemotherapy and the feasibility of an audiological monitoring program
(BioMed Central, 2017-12-11)Abstract Background Cisplatin is an anti-cancer chemotherapy drug classified as an alkylating agent. It is used for the treatment of a variety of cancers such as cervical, ... -
Perceptions about data-informed decisions : an assessment of information-use in high HIV-prevalence settings in South Africa
(BioMed Central, 2017-12-04)Background: Information-use is an integral component of a routine health information system and essential to influence policy-making, program actions and research. Despite an increased amount of routine data collected, ... -
Multiple and mixed methods in formative evaluation : is more better? reflections from a South African study
(BioMed Central, 2016)ENGLISH SUMMARY : Background: Formative programme evaluations assess intervention implementation processes, and are seen widely as a way of unlocking the 'black box' of any programme in order to explore and understand ... -
Researching complex interventions in health : the state of the art
(BMC Health Services Research, 2016)ENGLISH SUMMARY : Keynote presentations -
A partial economic evaluation of blended learning in teaching health research methods : a three-university collaboration in South Africa, Sweden, and Uganda
(Taylor & Francis Open, 2016)ENGLISH SUMMARY : Background: Novel research training approaches are needed in global health, particularly in sub-Saharan African universities, to support strengthening of health systems and services. Blended learning (BL), ... -
Student experiences of participating in five collaborative blended learning courses in Africa and Asia : a survey
(Taylor & Francis Open, 2016)ENGLISH SUMMARY : Background: As blended learning (BL; a combination of face-to-face and e-learning methods) becomes more commonplace, it is important to assess whether students find it useful for their studies. ARCADE ... -
Centella asiatica modulates cancer cachexia associated inflammatory cytokines and cell death in leukaemic THP-1 cells and peripheral blood mononuclear cells (PBMC’s)
(BioMed Central, 2017-08-01)Background: Cancer cachexia is associated with increased pro-inflammatory cytokine levels. Centella asiatica (C. asiatica) possesses antioxidant, anti-inflammatory and anti-tumour potential. We investigated the modulation ... -
Health-seeking behaviours of older black women living with non-communicable diseases in an urban township in South Africa
(BioMed Central, 2016)Background: Various studies have shown that non-communicable diseases (NCDs) especially diabetes and hypertension are prevalent among older women living in South African urban areas, placing a heavy burden on the healthcare ... -
A systematic review of economic evaluations of CHW interventions aimed at improving child health outcomes
(BioMed Central, 2017-02-28)ENGLISH SUMMARY : Evidence of the cost-effectiveness of community health worker interventions is pertinent for decision-makers and programme planners who are turning to community services in order to strengthen health ...
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