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Doctoral Degrees (Epidemiology and Biostatistics)
Recent Submissions
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Optimisation and benchmarking of analytical approaches to estimation of population level HIV incidence from survey data
(Stellenbosch : Stellenbosch University, 2022-04)ENGLISH SUMMARY: Disease prevalence (the proportion of a population with a condition of interest) is conceptually and procedurally much more straightforward to estimate than disease incidence (the rate of occurrence of new ... -
Assessment of point-of-care testing for prediction of aromatase inhibitor-associated side effects in obese postmenopausal breast cancer patients screened for cardiovascular risk factors
(Stellenbosch : Stellenbosch University, 2021-12)ENGLISH SUMMARY : Background: Aromatase inhibitors (AIs) constitute a standard of care for post- and premenopausal patients with estrogen receptor-positive breast cancer (BC). Obesity and mediators of inflammation have ... -
Burden of congenital rubella syndrome and potential impact of rubella vaccine introduction in South Africa
(Stellenbosch : Stellenbosch University, 2021-12)ENGLISH SUMMARY : Background: Introduction of rubella vaccines into public vaccination schedules of all countries is necessary if global rubella elimination is to be achieved. Rubella is targeted for elimination in five ... -
An evaluation of the effectiveness of task-shifting health systems approaches, including community-based and pharmaceutical care models, for HIV treatment and prevention programs in South Africa
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH SUMMARY : Southern Africa is the epicenter of the human immunodeficiency virus (HIV) pandemic having the highest burden of HIV globally. Although South Africa has made great strides with the roll-out of its ... -
Using quality improvement approach to address missed opportunities for vaccination in Kano Metropolis, Nigeria
(Stellenbosch : Stellenbosch University, 2019-12)ENGLISH SUMMARY : Background Strategies to reduce missed opportunities for vaccination (MOV) can potentially increase immunization coverage in health facilities and invariably improve immunization coverage at the district ... -
Transcutaneous bilirubin screening for hyperbilirubinemia in African newborns
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: In many parts of the world, including African countries, apparently healthy newborns are usually discharged home early. Serum bilirubin levels usually peaks on postnatal days 3 to 5, by when ... -
Understanding the relationship between vaccination, vaccine-preventable diseases, and HIV infection among sub-Saharan African children
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Numerous care and treatment guidelines pinpoint vaccination as a crucial preventive strategy for HIV-infected patients, but data regarding these vaccines among children living with HIV are still very ... -
Evaluation of the Mean Duration of Recent Infection (MDRI) and the False Recent Rate (FRR) for the Limiting Antigen Avidity Enzyme Immune Assay (LAg) and Bio-Rad HIV ½ Plus O Avidity Incidence Assay (BRAI)
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Background: The evaluation of laboratory assays in estimating HIV incidence has become a priority because of the complexity of HIV epidemics and the need to measure the impact of public health interventions ... -
The effects of longitudinal HIV viral load exposure on immune outcomes, mortality, and opportunistic infections in people on ART in sub-Saharan Africa
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Introduction: Longitudinal viral load monitoring is used as a cross-sectional marker for treatment failure in HIV infected people receiving antiretroviral therapy. Cumulative viral load, as quantified ...
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