Epidemiology and Biostatistics
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The use of error reporting data in patient safety research
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: Error reporting is the only data source designed specifically to generate patient safety data, yet its ability to report comprehensively on patient safety has not been assessed. This study ... -
Transcutaneous bilirubin screening for hyperbilirubinemia in African newborns
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: In many parts of the world, including African countries, apparently healthy newborns are usually discharged home early. Serum bilirubin levels usually peaks on postnatal days 3 to 5, by when ... -
Completeness of HIV intervention trial protocols : a systematic survey
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Introduction: The Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT1) 2013 guideline provides guidance to improve the quality of protocols. The aim of this study was to determine ... -
Barriers and facilitators to linkage, adherence and retention in care among HIV positive patients : an overview of qualitative systematic reviews using mega-aggregation framework synthesis
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: People living with Human Immunodeficiency Virus (PLHIV) continue to struggle with the complexities related to having a chronic disease and integrating antiretroviral treatment (ART) and care ... -
Prevalence of non-communicable diseases in adults living with Human Immunodeficiency Virus : an overview of systematic reviews
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: Non-communicable diseases (NCD’s) are on the rise in patients with HIV and this has been partly attributed to the increasing use of Antiretroviral therapy (ART). Our aim was to consolidate ... -
Mechanical debridement with antibiotics in the treatment of chronic periodontitis : effect on systemic biomarkers : a systematic review
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Background: Chronic periodontitis is an inflammatory oral disease which leads to the destruction of the supporting tissues of the teeth, leading to bone resorption and tooth loss. Destruction of the ... -
Understanding the relationship between vaccination, vaccine-preventable diseases, and HIV infection among sub-Saharan African children
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH SUMMARY : Numerous care and treatment guidelines pinpoint vaccination as a crucial preventive strategy for HIV-infected patients, but data regarding these vaccines among children living with HIV are still very ... -
Quality of life and physical activity among older adults living in institutions compared to the community
(AOSIS Publishing, 2017)Background: The environment of older adults plays an important role in their well-being. It influences their quality of life and physical activity level. In South Africa, there is a dearth of literature concerning this ... -
A cross sectional survey to evaluate knowledge, attitudes and practices regarding seasonal influenza and influenza vaccination among diabetics in Pretoria, South Africa
(Elsevier, 2017-11-07)Background: In South Africa, influenza vaccination is recommended to all diabetics. However, vaccinationcoverage among diabetics remains low. Therefore, this study aimed to explore the knowledge, attitudes,and practices ... -
Outcomes of community-based differentiated models of multi-month dispensing of antiretroviral medication among stable HIV-infected patients in Lesotho : a cluster randomised non-inferiority trial protocol
(BMC (part of Springer Nature), 2018-08-29)Background: Current World Health Organization (WHO) guidelines recommend early initiation of HIV positive patients on antiretroviral therapy (ART) irrespective of their clinical or immunological status known as the test ... -
Predictors of mortality in adults on treatment for human immunodeficiency virus-associated tuberculosis in Botswana : a retrospective cohort study
(Wolters Kluwer Health, 2018)Mortality in patients with human immunodeficiency virus (HIV)-associated tuberculosis (TB) is high, particularly in sub-Saharan Africa. This study aimed to compare mortality and predictors of mortality in those who were ... -
A comparative evaluation of PDQ-Evidence
(BioMed Central, 2018-03-15)Background: A strategy for minimising the time and obstacles to accessing systematic reviews of health system evidence is to collect them in a freely available database and make them easy to find through a simple ... -
Developing prehospital clinical practice guidelines for resource limited settings : why re-invent the wheel?
(BioMed Central, 2018-02-05)Objectives: Methods on developing new (de novo) clinical practice guidelines (CPGs) have received substantial attention. However, the volume of literature is not matched by research into alternative methods of CPG development ... -
Evaluation of the Mean Duration of Recent Infection (MDRI) and the False Recent Rate (FRR) for the Limiting Antigen Avidity Enzyme Immune Assay (LAg) and Bio-Rad HIV ½ Plus O Avidity Incidence Assay (BRAI)
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Background: The evaluation of laboratory assays in estimating HIV incidence has become a priority because of the complexity of HIV epidemics and the need to measure the impact of public health interventions ... -
The effects of longitudinal HIV viral load exposure on immune outcomes, mortality, and opportunistic infections in people on ART in sub-Saharan Africa
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Introduction: Longitudinal viral load monitoring is used as a cross-sectional marker for treatment failure in HIV infected people receiving antiretroviral therapy. Cumulative viral load, as quantified ... -
HIV infection and the epidemiology of Invasive Pneumococcal Disease (IPD) in South African adults and older children prior to the introduction of a Pneumococcal Conjugate Vaccine (PCV)
(Public Library of Science, 2016)Introduction: Streptococcus pneumoniae is the commonest cause of bacteremic pneumonia among HIV-infected persons. As more countries with high HIV prevalence are implementing infant pneumococcal conjugate vaccine (PCV) ... -
Epidemiology of urethral stricture at Tygerberg Hospital
(Health & Medical Publishing Group, 1994)Over a 12-month period, 120 consecutive male patients with confirmed urethral stricture were prospectively studied with regard to the epidemiology of the disease. Specific urethritis is the main aetiological factor (45%) ...
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