Browsing by Author "Van der Bijl, P."
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- ItemAminoglycoside monitoring: Perspective on current trends in the Western Cape(Health and Medical Publishing Group (HMPG), 2005) Van der Bijl, P.[No abstract available]
- ItemAuto-amputation of a breast due to ductal carcinoma(Health and Medical Publishing Group (HMPG), 2008) Van der Bijl, P.[No abstract available]
- ItemBlood oxygen saturation levels during conscious sedation with midazolam. A report of 16 cases(Health & Medical Publishing Group, 1986) Roelofse, J. A.; Van der Bijl, P.; Joubert, J. J.; Breytenbach, H. S.In a double-blind randomized study on 16 healthy individuals, two groups of subjects (8 in each group) received either midazolam (Dormicum; Roche) 0,1 mg/kg or placebo intravenously for conscious sedation during oral surgical procedures. Oxygen saturation of the blood was measured at different stages. Ten minutes after administration of the drug, the percentage oxygen saturation was significantly lower (P<0.05) in the midazolam group than in the placebo group.
- ItemOligomeric substances in ampicillin preparations : a comparison of Penbritin, Famicillin and Petercillin(Health & Medical Publishing Group, 1988) Van der Bijl, P.; Seifart, H. I.; Parkin, D. P.; Mattheyse, F. J.An investigation into the presence of potentially harmful oligomers in formulations of ampicillin for parenteral administration available in the RSA was undertaken by means of high-pressure liquid chromatography. Significant differences were found to exist between formulations.
- ItemPermeability of intestinal mucosa to crystalline and tabletted isoniazid (INH)(Health & Medical Publishing Group, 2003) Van der Bijl, P.; Seifart, H. I.; Van Eyk, A. D.When administered orally, isoniazid (INH), which continues to form the basis of most first-line standard antituberculosis regimens, reaches peak plasma concentrations of 3 - 5 μg/ml within 1 - 2 hours after ingestion of usual doses.1 Various tablet and slow-release matrix forms are available and these processed preparations are most often used clinically. However, various studies undertaken in our Department have shown crystalline INH to produce better blood levels within the first 2 hours after ingestion than the commonly used tabletted form.
- ItemPlasma cholinesterase levels during cardiopulmonary bypass : a report on 10 cases(Health & Medical Publishing Group, 1987) Roelofse, J. A.; Van der Bijl, P.Plasma cholinesterase levels of 10 male patients were determined before, during and after cardiopulmonary bypass surgery. These levels dropped significantly below the pre-anaesthetic values after commencing anaesthesia. In 6 patients levels returned to pre-anaesthetic values before or on the 2nd post-operative day. This could not be explained in terms of enzymic biosynthesis alone, and it is suggested that postoperative fluid readjustments may play an important role in certain cases.