Browsing by Author "Payne, K. A."
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- ItemEpidural versus intramuscular pethidine in postoperative pain relief(1983) Payne, K. A.Twenty-one patients received epidural pethidine 0,75 mg/kg in 10 ml normal saline for postoperative analgesia. A control group of 20 patients received intramuscular pethidine 1,5 mg/kg. Respiratory and cardiovascular parameters in both groups were stable, and in both side-effects were similar and not serious. In the epidural group analgesia was more intense and of longer duration and the level of consciousness was better. Central depression was present in both groups but less so in the epidural group.
- ItemIntramuscular buprenorphine compared with morphine for postoperative analgesia(Health & Medical Publishing Group, 1987) Payne, K. A.; Murray, W. B.; Barrett, H.The postoperative analgesic efficacy of buprenorphine (Temgesic; R & C Pharmaceuticals) 0,004 mg/kg and morphine 0,15 mg/kg were compared in 60 patients, both agents given by intramuscular injection. According to patients, buprenorphine gave better analgesia. There was no difference in the number of analgesic injections the two groups received in the 24-hour postoperative period. Cardiovascular and respiratory system were not depressed by either drug. Side-effects were not marked, nausea being the most common in both groups. Morphine had a greater effect on the mood of patients. Buprenorphine proved a satisfactory analgesic for postoperative use by intramuscular injection.
- ItemOral midazolam in paediatric premedication(Health & Medical Publishing Group, 1991) Payne, K. A.; Coetzee, A. R.; Mattheyse, F. J.; Dawes, T.In a premedication study involving 135 children, aged 1-10 years, four regimens were investigated: (i) no premedication; (ii) oral trimeprazine tartrate 2 mg/kg, methadone 0.1 mg/kg, droperidol 0.15 mg/kg (TMD); (iii) intramuscular midazolam (Dormicum; Roche) 0.15 mg/kg; and (iv) oral midazolam 0.45 mg/kg. All premedications were given 60 minutes before a standard halothane anaesthetic. No impairment of cardiovascular stability occurred but after premedication the mean oxygen saturation decreased by 1.6% and 1.1%, respectively, in the intramuscular midazolam and TMD groups. Overall, children under 5 years of age behaved less satisfactorily in the holding room and at induction, than those over 5 years (P<0.01). Midazolam, intramuscularly and orally, produced more satisfactory behaviour than the other two regimens (P<0.05) and, combined with a 70% more rapid recovery than the TMD regimen (P<0.05), suggests that oral midazolam is a more effective paediatric premedication agent than placebo or TMD.
- ItemRural anaesthetic practices in the Western Cape(Health & Medical Publishing Group, 1991) Payne, K. A.; Muller, C. J. B.; Coetzee, A. R.The findings of specialist anaesthetists on visits to rural towns in the western Cape over 6 years are reported. The importance of academic units communicating with general practitioners, nursing staff and hospital authorities in their own working environment is emphasised. Hospital anaesthetic facilities and general practice anaesthetic methods are discussed and recommendations made and, in addition, common problems that could improve anaesthesia in general practice are summarised.