Preanesthetic medication with rectal midazolam in children undergoing dental extractions

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dc.contributor.authorRoelofse J.A.
dc.contributor.authorVan der Bijl P.
dc.contributor.authorStegmann D.H.
dc.contributor.authorHartshorne J.E.
dc.date.accessioned2011-05-15T16:02:02Z
dc.date.available2011-05-15T16:02:02Z
dc.date.issued1990
dc.description.abstractThree different dosages (0.25, 0.35, and 0.45 mg/kg) of rectally administered midazolam were compared with each other and with placebo for preanesthetic medication in children undergoing dental extractions. Eighty patients between the ages of 2 and 10 years were randomly allocated into four groups in this double-blind study. The results from this trial show that 30 minutes after rectal administration of all doses of midazolam, good anxiolysis, sedation, and cooperation were obtained in most patients. A high prevalence (23%) of disinhibition reactions was observed, particularly in the 0.45 mg/kg group. For this reason, 0.25 or 0.35 mg/kg appears to be the dose of choice when rectal midazolam is used for premedication in children.
dc.description.versionArticle
dc.identifier.citationJournal of Oral and Maxillofacial Surgery
dc.identifier.citation48
dc.identifier.citation8
dc.identifier.issn2782391
dc.identifier.urihttp://hdl.handle.net/10019.1/12273
dc.subjectmidazolam
dc.subjectanesthesia
dc.subjectarticle
dc.subjectchild
dc.subjectconfusion
dc.subjectdental surgery
dc.subjecthuman
dc.subjectpremedication
dc.subjectpriority journal
dc.subjectpsychological aspect
dc.subjectrectal drug administration
dc.subjectvisual disorder
dc.subjectAdministration, Rectal
dc.subjectAnalysis of Variance
dc.subjectAnesthesia, Dental
dc.subjectAnesthesia, General
dc.subjectChi-Square Distribution
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectComparative Study
dc.subjectDouble-Blind Method
dc.subjectFemale
dc.subjectHuman
dc.subjectMale
dc.subjectMidazolam
dc.subjectPreanesthetic Medication
dc.subjectRandomized Controlled Trials
dc.subjectTooth Extraction
dc.titlePreanesthetic medication with rectal midazolam in children undergoing dental extractions
dc.typeArticle
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