Permeability of intestinal mucosa to crystalline and tabletted isoniazid (INH)

dc.contributor.author	Van der Bijl, P.	en_ZA
dc.contributor.author	Seifart, H. I.	en_ZA
dc.contributor.author	Van Eyk, A. D.	en_ZA
dc.date.accessioned	2011-03-18T14:57:03Z
dc.date.available	2011-03-18T14:57:03Z
dc.date.issued	2003
dc.description	CITATION: Van der Bijl, P., Seifart, H. I. & Van Eyk, A. D. 2003. Permeability of intestinal mucosa to crystalline and tabletted isoniazid (INH). South African Medical Journal, 93(2):127-128.
dc.description	The original publication is available at http://www.samj.org.za
dc.description.abstract	When administered orally, isoniazid (INH), which continues to form the basis of most first-line standard antituberculosis regimens, reaches peak plasma concentrations of 3 - 5 μg/ml within 1 - 2 hours after ingestion of usual doses.1 Various tablet and slow-release matrix forms are available and these processed preparations are most often used clinically. However, various studies undertaken in our Department have shown crystalline INH to produce better blood levels within the first 2 hours after ingestion than the commonly used tabletted form.
dc.description.version	Publisher’s version
dc.identifier.issn	2078-5135 (online)
dc.identifier.issn	0256-9574 (print)
dc.identifier.uri	http://hdl.handle.net/10019.1/7153
dc.language.iso	en
dc.publisher	Health & Medical Publishing Group
dc.rights.holder	South African Medical Journal
dc.subject	Isoniazid	en_ZA
dc.title	Permeability of intestinal mucosa to crystalline and tabletted isoniazid (INH)	en_ZA
dc.type	Article

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