The metabolic syndrome, insulin resistance and cardiovascular disease

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dc.contributor.authorAscott-Evans B.
dc.date.accessioned2011-05-15T15:56:43Z
dc.date.available2011-05-15T15:56:43Z
dc.date.issued2002
dc.description.abstractIn westernised societies the metabolic syndrome (MS) is common and primarily a lifestyle disease with significant morbidity and premature mortality. The main end-points are related to cardiovascular disease (CVD), especially affecting the heart. Although insulin resistance (and hyperinsulinaemia) is an early marker of MS and future adverse cardiovascular outcomes, it is not known if on its own this is sufficient. The issue is further clouded in prospective studies by the development in study subjects of some, or all of the components of MS, each of which is an independent risk factor for CVD! Therefore, in spite of a number of appropriate longterm observational studies, we are unable to tease out the exact contribution of the individual components of MS, which together are unequivocally responsible for this present-day epidemic of CVD.
dc.description.versionReview
dc.identifier.citationCardiovascular Journal of South Africa
dc.identifier.citation13
dc.identifier.citation4
dc.identifier.issn10159657
dc.identifier.urihttp://hdl.handle.net/10019.1/10007
dc.subjectcardiovascular disease
dc.subjectdisease marker
dc.subjecthuman
dc.subjecthyperinsulinemia
dc.subjectinsulin resistance
dc.subjectlifestyle
dc.subjectmetabolic disorder
dc.subjectmorbidity
dc.subjectmortality
dc.subjectnon insulin dependent diabetes mellitus
dc.subjectprospective study
dc.subjectreview
dc.subjectrisk factor
dc.subjectCardiovascular Diseases
dc.subjectHumans
dc.subjectInsulin Resistance
dc.subjectMetabolic Syndrome X
dc.subjectObesity
dc.subjectProspective Studies
dc.titleThe metabolic syndrome, insulin resistance and cardiovascular disease
dc.typeReview
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