Alcohol consumption and non-communicable diseases: Epidemiology and policy implications

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dc.contributor.authorParry C.D.
dc.contributor.authorPatra J.
dc.contributor.authorRehm J.
dc.date.accessioned2011-10-13T16:58:16Z
dc.date.available2011-10-13T16:58:16Z
dc.date.issued2011
dc.description.abstractAims This paper summarizes the relationships between different patterns of alcohol consumption and various on non-communicable disease (NCD) outcomes and estimates the percentage of NCD burden that is attributable to alcohol. Methods A narrative review, based on published meta-analyses of alcohol consumption-disease relations, together with an examination of the Comparative Risk Assessment estimates applied to the latest available revision of Global Burden of Disease study. Results Alcohol is causally linked (to varying degrees) to eight different cancers, with the risk increasing with the volume consumed. Similarly, alcohol use is related detrimentally to many cardiovascular outcomes, including hypertension, haemorrhagic stroke and atrial fibrillation. For other cardiovascular outcomes the relationship is more complex. Alcohol is furthermore linked to various forms of liver disease (particularly with fatty liver, alcoholic hepatitis and cirrhosis) and pancreatitis. For diabetes the relationship is also complex. Conservatively, of the global NCD-related burden of deaths, net years of life lost (YLL) and net disability adjusted life years (DALYs), 3.4%, 5.0% and 2.4%, respectively, can be attributed to alcohol consumption, with the burden being particularly high for cancer and liver cirrhosis. This burden is especially pronounced in countries of the former Soviet Union. Conclusions There is a strong link between alcohol and non-communicable diseases, particularly cancer, cardiovascular disease, liver disease, pancreatitis and diabetes, and these findings support calls by the World Health Organization to implement evidence-based strategies to reduce harmful use of alcohol. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.
dc.description.versionArticle
dc.identifier.citationAddiction
dc.identifier.citation106
dc.identifier.citation10
dc.identifier.citationhttp://www.scopus.com/inward/record.url?eid=2-s2.0-80052758517&partnerID=40&md5=1969a9c3bed7b124bd18236857ccf715
dc.identifier.issn9652140
dc.identifier.other10.1111/j.1360-0443.2011.03605.x
dc.identifier.urihttp://hdl.handle.net/10019.1/16666
dc.subjectAlcohol
dc.subjectBurden of disease
dc.subjectCancer
dc.subjectCardiovascular disease
dc.subjectLiver disease
dc.subjectNon-communicable diseases
dc.subjectPancreatitis
dc.titleAlcohol consumption and non-communicable diseases: Epidemiology and policy implications
dc.typeArticle
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