Management of tuberculosis in children and new treatment options

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dc.contributor.authorMarais B.J.
dc.contributor.authorSchaaf H.S.
dc.contributor.authorDonald P.R.
dc.date.accessioned2011-05-25T08:49:51Z
dc.date.available2011-05-25T08:49:51Z
dc.date.issued2011
dc.description.abstractChildhood tuberculosis (TB) continues to be a neglected disease in areas where limited resources restrict the focus of national TB control programmes to only the most infectious sputum smear-positive cases. However, appreciation that children contribute a significant proportion to the global TB disease burden and suffer severe TB-related morbidity and mortality is growing. The World Health Organization (WHO) published guidelines on the management of paediatric TB in 2006 and child friendly drug formulations have been made available to deserving nations via the Global Drug Facility (GDF) since 2008. These advances also served to emphasize the considerable programmatic barriers that remain in resource- limited settings. This review provides an overview of current treatment practices, presenting the authors personal perspectives on issues related to the treatment of childhood TB, together with a brief synopsis of potential future treatment options. © 2011 Bentham Science Publishers Ltd.
dc.description.versionArticle
dc.identifier.citationInfectious Disorders - Drug Targets
dc.identifier.citation11
dc.identifier.citation2
dc.identifier.citation144
dc.identifier.citation156
dc.identifier.issn18715265
dc.identifier.urihttp://hdl.handle.net/10019.1/14715
dc.titleManagement of tuberculosis in children and new treatment options
dc.typeArticle
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