Comparison of sublingual lorazepam with intramuscular diazepam as sedatives during oral surgery

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dc.contributor.authorVan Der Bijl P.
dc.contributor.authorRoelofse J.A.
dc.contributor.authorDe Joubert V.J.J.
dc.date.accessioned2011-05-15T16:02:02Z
dc.date.available2011-05-15T16:02:02Z
dc.date.issued1988
dc.description.abstractSublingual lorazepam (2 to 3 mg) was compared with intramuscular diazepam (0.25 mg/kg) and placebo for sedation during oral surgery under local anesthesia. Sixty patients were randomly allocated into three groups in this double-blind, parallel study. The results from this trial show that sublingually administered lorazepam provided good sedation and anxiolysis. More side-effects, such as giddiness, dizziness, and ptosis, as well as profound and prolonged psychomotor impairment, were, however, found in the lorazepam group than in those patients who had received intramuscular diazepam (0.25 mg/kg) or placebo.
dc.description.versionArticle
dc.identifier.citationJournal of Oral and Maxillofacial Surgery
dc.identifier.citation46
dc.identifier.citation7
dc.identifier.issn2782391
dc.identifier.urihttp://hdl.handle.net/10019.1/12276
dc.subjectdiazepam
dc.subjectlorazepam
dc.subjectcontrolled study
dc.subjecthuman
dc.subjectintramuscular drug administration
dc.subjectlocal anesthesia
dc.subjectmajor clinical study
dc.subjectoral surgery
dc.subjectpriority journal
dc.subjectptosis
dc.subjectsedation
dc.subjectsublingual drug administration
dc.subjectvertigo
dc.subjectAdministration, Sublingual
dc.subjectAdolescent
dc.subjectAdult
dc.subjectComparative Study
dc.subjectDiazepam
dc.subjectDouble-Blind Method
dc.subjectFemale
dc.subjectHuman
dc.subjectInjections, Intramuscular
dc.subjectLorazepam
dc.subjectMale
dc.subjectPreanesthetic Medication
dc.subjectRandom Allocation
dc.subjectStatistics
dc.subjectTablets
dc.subjectTooth Extraction
dc.titleComparison of sublingual lorazepam with intramuscular diazepam as sedatives during oral surgery
dc.typeArticle
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