A comparison of 4-week peptic ulcer healing rates following treatment with antacids and ranitidine

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dc.contributor.authorBezuidenhout, D. J. J.
dc.contributor.authorPerold, J. G.
dc.contributor.authorAdams, G.
dc.date.accessioned2011-03-18T14:59:44Z
dc.date.available2011-03-18T14:59:44Z
dc.date.issued1984-06
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractEighty-eight patients with endoscopically proven gastric and duodenal ulceration were treated with ranitidine (Zantac; Glaxo) or an antacid preparation containing aluminium hydroxide and magnesium trisilicate (Gelusil; Warner) over a 4-week period to assess healing. Clinical, haematological and biochemical assessment and endoscopy were performed at the beginning and at the end of this period. Of the duodenal ulcers, 74% healed on ranitidine therapy and 63% on Gelusil. This difference was not statistically significant (χ2(1) = 0,55). Of the gastric ulcers 58% healed on ranitidine therapy and 35% on Gelusil, but this difference did not reach statistical significance (χ2(1) = 1,79). There was no significant difference between the two therapies with regard to symptomatic relief in the duodenal ulcer group, but ranitidine produced significantly better results in the gastric ulcer group. No side-effects were noted in either group.en_ZA
dc.description.versionPublishers' Version
dc.format.extentp. 1007-1009
dc.identifier.citationBezuidenhout, D. J. J., Perold, J. G. & Adams, G. 1984. A comparison of 4-week peptic ulcer healing rates following treatment with antacids and ranitidine. South African Medical Journal, 65(1007-1009).
dc.identifier.urihttp://hdl.handle.net/10019.1/8024
dc.language.isoen_ZA
dc.publisherHealth and Medical Publishing Group (HMPG)
dc.rights.holderSAMJ reserves copyright of the material published
dc.subjectPeptic ulcer -- Treatmenten_ZA
dc.subjectAntacidsen_ZA
dc.subjectRanitidineen_ZA
dc.titleA comparison of 4-week peptic ulcer healing rates following treatment with antacids and ranitidineen_ZA
dc.typeArticle
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