Fall history and associated factors among adults living with HIV-1 in the Cape Winelands, South Africa : an exploratory investigation

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dc.contributor.authorBerner, Karinaen_ZA
dc.contributor.authorStrijdom, Hansen_ZA
dc.contributor.authorEssop, M. Faadielen_ZA
dc.contributor.authorWebster, Ingriden_ZA
dc.contributor.authorMorris, Linzetteen_ZA
dc.contributor.authorLouw, Quinetteen_ZA
dc.date.accessioned2019-10-15T14:09:03Z
dc.date.available2019-10-15T14:09:03Z
dc.date.issued2019
dc.descriptionCITATION: Berner, K., et al. 2019. Fall history and associated factors among adults living with HIV-1 in the Cape Winelands, South Africa : an exploratory investigation. Open Forum Infectious Diseases, 6(10):ofz401, doi:10.1093/ofid/ofz401.
dc.descriptionThe original publication is available at https://academic.oup.com/ofid
dc.descriptionPublication of this article was funded by the Stellenbosch University Open Access Fund.
dc.description.abstractBackground. People with HIV-1 (PWH) exhibit a high fall incidence and increased fracture risk. As little is known about fall frequency and associated factors in PWH residing in lower-middle-income countries (LMIC), we investigated fall frequency, bone quality, and factors associated with fall history in a South African cohort. Methods. Fifty PWH without obvious predisposing factors for mobility impairments attending 2 public primary care clinics in the Western Cape region participated. Demographic, clinical, and physical performance data were collected. Falls were assessed retrospectively over 12 months. Mobility and balance were evaluated using a physical performance battery. Bone mineral density was screened using quantitative ultrasound (QUS). Associations between variables and falls grouping were analyzed using chi-square tests, t tests, and Mann-Whitney U tests, and effect sizes (ES) were calculated. Results. Thirty-four percent of PWH (median age, 36.6 years) reported falling during the past year, and 41.2% of fallers reported multiple falls. Fallers had more mobility problems (P = .013), higher fear of falling (P = .007), higher fracture history (P = .003), worse balance performance (P < .001), higher proportions of detectable viral loads (P = .021), and poorer bone quality (P = .040). Differences were of medium to large ES. Conclusions. This exploratory study is the first to show that relatively young South African PWH without obvious predisposing factors for gait and balance impairments experience falls. The observed fall-associated factors warrant further research using larger samples and longitudinal designs to ascertain fall predictors within this population.en_ZA
dc.description.urihttps://academic.oup.com/ofid/article/6/10/ofz401/5584296
dc.description.versionPublisher's version
dc.format.extent7 pages ; illustrations
dc.identifier.citationBerner, K., et al. 2019. Fall history and associated factors among adults living with HIV-1 in the Cape Winelands, South Africa : an exploratory investigation. Open Forum Infectious Diseases, 6(10):ofz401, doi:10.1093/ofid/ofz401
dc.identifier.issn2328-8957 (online)
dc.identifier.otherdoi:10.1093/ofid/ofz401
dc.identifier.urihttp://hdl.handle.net/10019.1/106648
dc.language.isoen_ZAen_ZA
dc.publisherOxford University Press
dc.rights.holderAuthors retain copyright
dc.subjectBone qualityen_ZA
dc.subjectFalls (Accidents) -- Boland (South Africa)en_ZA
dc.subjectHIV-positive persons -- Boland (South Africa)en_ZA
dc.titleFall history and associated factors among adults living with HIV-1 in the Cape Winelands, South Africa : an exploratory investigationen_ZA
dc.typeArticleen_ZA
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