Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study)

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dc.contributor.authorSnyman, Yolandien_ZA
dc.contributor.authorWhitelaw, Andrew C.en_ZA
dc.contributor.authorMaloba, Motlatji R. B.en_ZA
dc.contributor.authorHesseling, Anneke C.en_ZA
dc.contributor.authorNewton-Foot, Maeen_ZA
dc.date.accessioned2021-08-19T09:49:51Z
dc.date.available2021-08-19T09:49:51Z
dc.date.issued2021
dc.descriptionCITATION: Snyman, Y., et al. 2021. Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study). Southern African Journal of Infectious Diseases, 36(1):a241, doi:10.4102/sajid.v36i1.241.
dc.descriptionThe original publication is available at https://sajid.co.za
dc.descriptionPublication of this article was funded by the Stellenbosch University Open Access Fund
dc.description.abstractENGLISH ABSTRACT: Colistin is a last-resort antibiotic against multidrug-resistant, Gram-negative bacteria. Colistin resistance has been described in the clinical settings in South Africa. However, information on carriage of these bacteria in communities is limited. This study investigated gastrointestinal carriage of colistin-resistant Escherichia coli and Klebsiella spp. and mcr genes in children from communities in Cape Town. Colistin-resistant E. coli was isolated from two participants (4%, 2/50), and mcr-1-mcr-9 genes were not detected. Gastrointestinal carriage of colistin-resistant Enterobacterales was rare; however, continuous extensive surveillance is necessary to determine the extent of carriage and its contribution to resistance observed in clinical settings.en_ZA
dc.description.urihttps://sajid.co.za/index.php/sajid/article/view/241
dc.description.versionPublisher's version
dc.format.extent4 pagesen_ZA
dc.identifier.citationSnyman, Y., et al. 2021. Carriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study). Southern African Journal of Infectious Diseases, 36(1):a241, doi:10.4102/sajid.v36i1.241
dc.identifier.issn2313-1810 (online)
dc.identifier.issn2312-0053 (print)
dc.identifier.otherdoi:10.4102/sajid.v36i1.241
dc.identifier.urihttp://hdl.handle.net/10019.1/110887
dc.language.isoen_ZAen_ZA
dc.publisherAOSISen_ZA
dc.rights.holderAuthors retain copyrighten_ZA
dc.subjectEnterobacteralesen_ZA
dc.subjectAntibacterial agentsen_ZA
dc.subjectGram-negative bacteriaen_ZA
dc.subjectTuberculosis in childrenen_ZA
dc.subjectColistinen_ZA
dc.subjectMultidrug resistanceen_ZA
dc.titleCarriage of colistin-resistant Gram-negative bacteria in children from communities in Cape Town (Tuberculosis child multidrug-resistant preventive therapy trial sub-study)en_ZA
dc.typeArticleen_ZA
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