Holoprosencephaly : the use of magnetic resonance imaging and application in antenatal diagnosis

dc.contributor.authorKolovos, I. G.en_ZA
dc.contributor.authorSmith, R. M. L.en_ZA
dc.date.accessioned2011-03-18T14:57:14Z
dc.date.available2011-03-18T14:57:14Z
dc.date.issued1993
dc.descriptionCITATION: Kolovos, I. G. & Smith, R. M. L. 1993. Holoprosencephaly : the use of magnetic resonance imaging and application in antenatal diagnosis. South African Medical Journal, 83:68-69.
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractHoloprosencephaly is the result of disordered organogenesis within the central nervous system where the forebrain fails to undergo diverticulation and development between rhe 4th and 8rh week of fetal life.' It is associated with facial abnormalities. It is a rare condition (1:5200 to 1:16000 live births), usually diagnosed by antenatal ultrasound scanning.' This, however, represents 16% or more of all cases of fetal hydrocephalus detected.' In view of the serious nature of this condition, recognition of its morphological appearance on ultrasound examination is important to direct further management and patient counselling.
dc.description.versionPublisher’s version
dc.identifier.issn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7284
dc.language.isoen
dc.publisherHealth & Medical Publishing Group
dc.rights.holderSouth African Medical Journal
dc.subjectMagnetic resonance imagingen_ZA
dc.titleHoloprosencephaly : the use of magnetic resonance imaging and application in antenatal diagnosisen_ZA
dc.typeArticle
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