Holoprosencephaly : the use of magnetic resonance imaging and application in antenatal diagnosis
Date
1993
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
Holoprosencephaly is the result of disordered
organogenesis within the central nervous system
where the forebrain fails to undergo diverticulation and
development between rhe 4th and 8rh week of fetal life.' It
is associated with facial abnormalities. It is a rare condition
(1:5200 to 1:16000 live births), usually diagnosed by antenatal
ultrasound scanning.' This, however, represents 16%
or more of all cases of fetal hydrocephalus detected.' In
view of the serious nature of this condition, recognition of
its morphological appearance on ultrasound examination is
important to direct further management and patient counselling.
Description
CITATION: Kolovos, I. G. & Smith, R. M. L. 1993. Holoprosencephaly : the use of magnetic resonance imaging and application in antenatal diagnosis. South African Medical Journal, 83:68-69.
The original publication is available at http://www.samj.org.za
The original publication is available at http://www.samj.org.za
Keywords
Magnetic resonance imaging