SMS nudges as a tool to reduce tuberculosis treatment delay and pretreatment loss to follow-up. A randomized controlled trial

dc.contributor.authorWagstaff, Adamen_ZA
dc.contributor.authorVan Doorslaer, Eddyen_ZA
dc.contributor.authorBurger, Ronelleen_ZA
dc.date.accessioned2021-09-28T12:59:27Z
dc.date.available2021-09-28T12:59:27Z
dc.date.issued2019
dc.descriptionCITATION: Wagstaff, A., Van Doorslaer, E. & Burger, R. 2019. SMS nudges as a tool to reduce tuberculosis treatment delay and pretreatment loss to follow-up. A randomized controlled trial. PLoS ONE, 14(6):e0218527, doi:10.1371/journal.pone.0218527.
dc.descriptionThe original publication is available at https://journals.plos.org/plosone/
dc.description.abstractBackground: TB persists despite being relatively easy to detect and cure because the journey from the onset of symptoms to cure involves a series of steps, with patients being lost to follow-up at each stage and delays occurring among patients not lost to follow-up. One cause of drop-off and delay occurs when patients delay or avoid returning to clinic to get their test results and start treatment. Methods: We fielded two SMS interventions in three Cape Town clinics to see their effects on whether people returned to clinic, and how quickly. One was a simple reminder; the other aimed to overcome “optimism bias” by reminding people TB is curable and many millions die unnecessarily from it. Recruits were randomly assigned at the clinic level to a control group or one of the two SMS groups (1:2:2). In addition to estimating effects on the full sample, we also estimated effects on HIV-positive patients. Results: SMS recipients were more likely to return to clinic in the requested two days than the control group. The effect was smaller in the intent-to-treat analysis (52/101 or 51.5% vs. 251/405 or 62.0%, p = 0.05) than in the per-protocol analysis (50/97 or 51.5% vs. 204/318 or 64.2%, p = 0.03). The effect was larger among HIV-positives (10/35 or 28.6% vs. 97/149 or 65.1%, p<0.01). The effects of SMS messages diminished as the interval increased: significant effects at the 5% level were found at five and 10 days only among HIV-positives. The second SMS message had larger effects, albeit not significantly larger, likely due in part to lack of statistical power. Conclusions: At 2 U.S. cents per message, SMS reminders are an inexpensive option to encourage TB testers to return to clinic, especially when worded to counter optimism bias.en_ZA
dc.description.urihttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218527
dc.description.versionPublisher's version
dc.format.extent14 pages ; illustrations
dc.identifier.citationWagstaff, A., Van Doorslaer, E. & Burger, R. 2019. SMS nudges as a tool to reduce tuberculosis treatment delay and pretreatment loss to follow-up. A randomized controlled trial. PLoS ONE, 14(6):e0218527, doi:10.1371/journal.pone.0218527
dc.identifier.issn1932-6203 (online)
dc.identifier.otherdoi:10.1371/journal.pone.0218527
dc.identifier.urihttp://hdl.handle.net/10019.1/123090
dc.language.isoen_ZAen_ZA
dc.publisherPublic Library of Science
dc.rights.holderAuthors retain copyright
dc.subjectTuberculosis -- Treatmenten_ZA
dc.subjectWireless communication systems in medical careen_ZA
dc.subjectTuberculosis -- Information servicesen_ZA
dc.subjectText messaging (Cell phone systems)en_ZA
dc.titleSMS nudges as a tool to reduce tuberculosis treatment delay and pretreatment loss to follow-up. A randomized controlled trialen_ZA
dc.typeArticleen_ZA
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