Recent Submissions

  • Technology led to more abstract causal reasoning 

    Gardenfors, Peter; Lombard, Marlize (Springer, 2020-07-06)
    Many animal species use tools, but human technical engagement is more complex. We argue that there is coevolution between technical engagement (the manufacturing and use of tools) and advanced forms of causal cognition in ...
  • Parenting children who are enterally fed: How families go from surviving to thriving 

    Hopwood, Nick; Elliot, Chris; Moraby, Khadeejah; Dadich, Ann (Wiley, 2020-09-09)
    Background Complex feeding difficulties requiring enteral (tube) feeding affect everyone around the child. Parents experience additional stress and are at risk of social isolation. This study investigated the strategies ...
  • On borders, boundaries and being a chameleon: Metaphors for reframing the academic project 

    van Schalkwyk, Susan (2017-09)
    Susan van Schalkwyk, MPhil PhD, is Professor in Health Professions Education and Director of the Centre for Health Professions Education in the Faculty of Medicine and Health Sciences (FMHS) at Stellenbosch University, ...
  • Variable contribution identification and visualization in multivariate statistical process monitoring 

    Rossouw, R. F.; Coetzer, R. L. J.; Le Roux, N. J. (Elsevier, 2020-01-15)
    Multivariate statistical process monitoring (MSPM) has received book-length treatments and wide spread application in industry. In MSPM, multivariate data analysis techniques such as principal component analysis (PCA) are ...
  • Remdesivir for severe covid-19: a clinical practice guideline 

    Rochwerg, Bram; Agarwal, Arnav; Zeng, Linan; Leo, Yee-Sin; Appiah, John Adabie; Agoritsas, Thomas; Bartoszko, Jessica; Brignardello-Petersen, Romina; Ergan, Begum; Ge, Long; Geduld, Heike; Gershengorn, Hayley B.; Manai, Hela; Huang, Minhua; Lamontagne, François; Kanda, Seema; Kawano-Dourado, Leticia; Kurian, Linda; Kwizera, Arthur; Murthy, Srinivas; Qadir, Nida; Siemieniuk, Reed; Silvestre, Maria Asuncion; Vandvik, Per Olav; Ye, Zhikang; Zeraatkar, Dena; Guyatt, Gordon (2020-11-23)
    Clinical question What is the role of remdesivir in the treatment of severe covid-19? This guideline was triggered by the ACTT-1 trial published in the New England Journal of Medicine on 22 May 2020. Current practice ...
  • A living WHO guideline on drugs for covid-19 

    Agarwal, Arnav; Rochwerg, Bram; Lamontagne, François; Siemieniuk, Reed AC; Agoritsas, Thomas; Askie, Lisa; Lytvyn, Lyubov; Leo, Yee-Sin; Macdonald, Helen; Zeng, Linan; Amin, Wagdy; Barragan, Fabian A Jaimes; Bausch, Frederique J.; Burhan, Erlina; Calfee, Carolyn S.; Cecconi, Maurizio; Chanda, Duncan; Dat, Vu Quoc; De Sutter, An; Du, Bin; Freedman, Stephen; Geduld, Heike; Gee, Patrick; Gotte, Matthias; Harley, Nerina; Hashmi, Madiha; Hunt, Beverley; Jehan, Fyezah; Kabra, Sushil K.; Kanda, Seema; Kim, Yae-Jean; Kissoon, Niranjan; Krishna, Sanjeev; Kuppalli, Krutika; Kwizera, Arthur; Castro-Rial, Marta Lado; Lisboa, Thiago; Lodha, Rakesh; Mahaka, Imelda; Manai, Hela; Mino, Greta; Nsutebu, Emmanuel; Preller, Jacobus; Pshenichnaya, Natalia; Qadir, Nida; Relan, Pryanka; Sabzwari, Saniya; Sarin, Rohit; Shankar-Hari, Manu; Sharland, Michael; Shen, Yinzhong; Ranganathan, Shalini S.; Souza, Joao P.; Stegemann, Miriam; Swanstrom, Ronald; Ugarte, Sebastian; Uyeki, Tim; Venkatapuram, Sridhar; Vuyiseka, Dubula; Wijewickrama, Ananda; Tran, Lien; Zeraatkar, Dena; Bartoszko, Jessica J.; Ge, Long; Brignardello-Petersen, Romina; Owen, Andrew; Guyatt, Gordon; Diaz, Janet; Kawano-Dourado, Leticia; Jacobs, Michael; Vandvik, Per Olav (2022-04-22)
    This living guideline by Arnav Agarwal and colleagues (BMJ 2020;370:m3379, doi:10.1136/bmj.m3379) was last updated on 22 April 2022, but the infographic contained two dosing errors: the dose of ritonavir with renal failure ...
  • Mammography reporting at Tygerberg Hospital, Cape Town, South Africa 

    Pitcher, Richard; Lotz, Jan; Ackermann, Christelle; Bagadia, Asif; Davis, Razaan; Du Plessis, Anne-Marie; Griffith-Richards, Stephanie; Hattingh, Retha; Wagener, Georg; Apffelstaedt, Justus; Dalmayer, Lisa; Baatjes, Karin (Health & Medical Publishing Group, 2014-05-19)
    In their recent article, Apffelstaedt et al.[1] analysed 16 105 mammograms performed at Tygerberg Hospital (TBH), Cape Town, South Africa (SA), between 2003 and 2012. The summary reported that ‘mammograms were read by ...
  • How to manage obsessive-compulsive disorder (OCD) under COVID-19 : a clinician's guide from the International College of Obsessive Compulsive Spectrum Disorders (ICOCS) and the Obsessive-Compulsive and Related Disorders Research Network (OCRN) of the European College of Neuropsychopharmacology 

    Fineberg, N. A.; Van Ameringen, M.; Drummond, L.; Hollander, E.; Stein, D. J.; Geller, D.; Walitza, S.; Pallanti, S.; Pellegrini, L.; Zohar, J.; Rodriguez, C. I.; Menchon, J. M.; Morgado, P.; Mpavaenda, D.; Fontenelle, L. F.; Feusner, J. D.; Grassi, G.; Lochner, C.; Veltman, D. J.; Sireau, N.; Carmi, L.; Adam, D.; Nicolini, H.; Dell'Osso, B. (Elsevier Inc., 2020-07)
    The rapid advance of the coronavirus COVID-19 pandemic has significantly increased mortality but also has demonstrated considerable potential to negatively impact mental health, including in the young [1,2]. From a ...
  • Preventing problematic internet use during the COVID-19 pandemic : consensus guidance 

    Király, Orsolya; Potenza, Marc N.; Stein, Dan J.; King, Daniel L.; Hodgins, David C.; Saunders, John B.; Griffiths, Mark D.; Gjoneska, Biljana; Billieux, Joël; Brand, Matthias; Abbott, Max W.; Chamberlain, Samuel R.; Corazza, Ornella; Burkauskas, Julius; Sales, Célia M. D.; Montag, Christian; Lochner, Christine; Grünblatt, Edna; Wegmann, Elisa; Martinotti, Giovanni; Lee, Hae Kook; Rumpf, Hans-Jürgen; Castro-Calvo, Jesús; Rahimi-Movaghar, Afarin; Higuchi, Susumu; Menchon, Jose M.; Zohar, Joseph; Pellegrini, Luca; Walitza, Susanne; Fineberg, Naomi A.; Demetrovics, Zsolt (Elsevier Inc, 2020-07)
    As a response to the COVID-19 pandemic, many governments have introduced steps such as spatial distancing and "staying at home" to curb its spread and impact. The fear resulting from the disease, the 'lockdown' situation, ...
  • Understanding the underlying drivers of obesity in Africa : a scoping review protocol 

    Jaca, Anelisa; Iwu, Chinwe; Durão, Solange; Onyango, Adelheid W.; Wiysonge, Charles Shey (BMJ Publishing, 2020-11-11)
    Introduction: The worldwide prevalence of obesity and overweight has doubled since 1980, such that approximately a third of the world's population is reported as obese or overweight. Obesity rates have increased in all ...
  • Contextualised strategies to increase childhood and adolescent vaccination coverage in South Africa : a mixed-methods study 

    Wiysonge, Charles Shey; Mahasha, Phetole Walter; Ndwandwe, Duduzile Edith; Ngcobo, Ntombenhle; Grimmer, Karen; Dizon, Janine; Burnett, Rosemary J.; Cooper, Sara (BMJ Publishing, 2020-06-04)
    Introduction Despite the unparalleled success of immunisation in the control of vaccine preventable diseases, immunisation coverage in South Africa remains suboptimal. While many evidence-based interventions have successfully ...
  • Epidemiology of multimorbidity among people living with HIV in sub-Saharan Africa : a systematic review protocol 

    Oladimeji, Kelechi Elizabeth; Dzomba, Armstrong; Adetokunboh, Olatunji; Zungu, Lindiwe; Yaya, Sanni; Ter Goon, Daniel (BMJ Publishing, 2020-12-12)
    Introduction Sub-Saharan Africa remains the epicentre of the HIV pandemic, yet enormous knowledge gaps still exist to elicit a comprehensive portrait of multimorbidity and HIV linkage. This study aims to conduct a systematic ...
  • Taking stock of vaccine hesitancy among migrants : a scoping review protocol 

    Tankwanchi, Akhenaten Siankam; Jaca, Anelisa; Larson, Heidi J.; Wiysonge, Charles S.; Vermund, Sten H. (BMJ Publishing, 2020-05-12)
    Introduction At the 72nd World Health Assembly of May 2019, WHO member states prioritised a global action plan to promote migrant and refugee health. Five months earlier, WHO had declared vaccine hesitancy—the reluctance ...
  • Reporting of methodological studies in health research : a protocol for the development of the MethodologIcal STudy reportIng Checklist (MISTIC) 

    Lawson, Daeria O.; Puljak, Livia; Pieper, Dawid; Schandelmaier, Stefan; Collins, Gary S.; Brignardello-Petersen, Romina; Moher, David; Tugwell, Peter; Welch, Vivian A.; Samaan, Zainab; Thombs, Brett D.; Nørskov, Anders K.; Jakobsen, Janus C.; Allison, David B.; Mayo-Wilson, Evan; Young, Taryn; Chan, An-Wen; Briel, Matthias; Guyatt, Gordon H.; Thabane, Lehana; Mbuagbaw, Lawrence (BMJ Publishing, 2020-12-17)
    Introduction Methodological studies (ie, studies that evaluate the design, conduct, analysis or reporting of other studies in health research) address various facets of health research including, for instance, data collection ...
  • Evidence for Better Lives Study : a comparative birth-cohort study on child exposure to violence and other adversities in eight low- and middle-income countries - foundational research (study protocol) 

    Valdebenito, Sara; Murray, Aja; Hughes, Claire; Băban, Adriana; Fernando, Asvini D.; Madrid, Bernadette J.; Ward, Catherine; Osafo, Joseph; Dunne, Michael; Sikander, Siham; Walker, Susan P.; Van Thang, Vo; Tomlinson, Mark; Fearon, Pasco; Shenderovich, Yulia; Marlow, Marguerite; Chathurika, Deshanie; Taut, Diana; Eisner, Manuel (BMJ Publishing, 2020-10-10)
    Introduction Violence against children is a health, human rights and social problem affecting approximately half of the world’s children. Its effects begin at prenatal stages with long-lasting impacts on later health and ...
  • Exploration of rural physicians’ lived experience of practising outside their usual scope of practice to provide access to essential medical care (clinical courage) : an international phenomenological study 

    Konkin, Jill; Grave, Laura; Cockburn, Ella; Couper, Ian; Stewart, Ruth Alison; Campbell, David; Walters, Lucie (BMJ Publishing, 2020-08-26)
    Objectives Rural doctors describe consistent pressure to provide extended care beyond the limits of their formal training in order to meet the needs of the patients and communities they serve. This study explored the lived ...
  • Achieving universal health coverage for people with stroke in South Africa : protocol for a scoping review 

    Van Niekerk, Sjan-Mari; Inglis-Jassiem, Gakeemah; Kamalakannan, Sureshkumar; Fernandes, Silke; Webster, Jayne; English, Rene; Smythe, Tracey; Louw, Q. A. (BMJ Publishing, 2020-10-12)
    Introduction Stroke is the second most common cause of death after HIV/AIDS and a significant health burden in South Africa. The extent to which universal health coverage (UHC) is achieved for people with stroke in South ...
  • Falls in people living with HIV : a scoping review 

    Charumbira, Maria Yvonne; Berner, Karina; Louw, Quinette Abegail (BMJ Open, 2020-11-03)
    Objectives Recent research has indicated seemingly increased propensity for falls and accelerated bone demineralisation in people living with HIV (PLWH). We aim to map out the extent and nature of existing research relating ...
  • ‘Building on shaky ground’—challenges to and solutions for primary care guideline implementation in four provinces in South Africa : a qualitative study 

    Kredo, Tamara; Cooper, Sara; Abrams, Amber Louise; Muller, Jocelyn; Schmidt, Bey-Marrié; Volmink, Jimmy; Atkins, Salla (BMJ Publishing, 2020-05-30)
    Objectives Clinical guidelines support evidence-informed quality patient care. Our study explored perspectives of South African subnational health managers regarding barriers to and enablers for implementation for all ...
  • Does economic growth reduce childhood stunting? A multicountry analysis of 89 demographic and health surveys in sub-Saharan Africa 

    Yaya, Sanni; Uthman, Olalekan A.; Kunnuji, Michael; Navaneetham, Kannan; Akinyemi, Joshua O.; Kananura, Rornald Muhumuza; Adjiwanou, Visseho; Adetokunboh, Olatunji; Bishwajit, Ghose (BMJ Publishing, 2020-01-23)
    Background There is mixed evidence and lack of consensus on the impact of economic development on stunting, and likewise there is a dearth of empirical studies on this relationship in the case of sub-Saharan Africa. Thus, ...

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