Research Articles (Neurology)
Recent Submissions
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Emerging differences between Huntington's disease-like 2 and Huntington's disease : a comparison using MRI brain volumetry
(Elsevier, 2019)ENGLISH ABSTRACT: Huntington's Disease-Like 2 (HDL2), caused by a CTG/CAG expansion in JPH3 on chromosome 16q24, is the most common Huntington's Disease (HD) phenocopy in populations with African ancestry. Qualitatively, ... -
EEG source connectivity to localize the seizure onset zone in patients with drug resistant epilepsy
(Elsevier, 2017-09)ENGLISH ABSTRACT: the presurgical evaluation of epilepsy as a reflection of the irritative zone. ESI of ictal scalp EEG to localize the seizure onset zone (SOZ) remains challenging. We investigated the value of an approach ... -
Clinical findings and genetic screening for copy number variation mutations in a cohort of South African patients with Parkinson’s disease
(Health & Medical Publishing Group, 2016)ENGLISH ABSTRACT: Background. Parkinson’s disease (PD), with a prevalence of up to 4% in Western countries, appears to be less common in Africa, possibly in part because of genetic factors. African studies investigating ... -
Peritoneal dialysis technique survival at Tygerberg Hospital in Cape Town, South Africa
(African Association of Nephrology, 2017)Background: The use of peritoneal dialysis (PD) as a treatment modality for patients with end-stage renal disease (ESRD) has been declining in many countries over the past few years. One of the reasons is technique failure, ... -
Listerial brainstem encephalitis – treatable, but easily missed
(Health & Medical Publishing Group, 2015)ENGLISH ABSTRACT: Listerial brainstem encephalitis (LBE) is an uncommon form of listerial central nervous system infection that progresses rapidly and is invariably fatal unless detected and treated early. We report on six ... -
A putative founder effect for Parkinson’s disease in South African Afrikaners
(Health & Medical Publishing Group, 2014-06)There is evidence for a founder effect for Parkinson’s disease in South African Afrikaners. This finding is of importance for two reasons. Firstly, given that established genetic causes of PD have not been identified in ... -
Stem cell therapy and amyotrophic lateral sclerosis
(Health and Medical Publishing Group (HMPG), 2012-06)We have been made aware of several patients with neurological diseases attending stem cell therapy centres, and in particular individuals with amyotrophic lateral sclerosis (ALS). The opening of stem cell clinics in ... -
Reliability and diagnostic performance of CT imaging criteria in the diagnosis of Tuberculous Meningitis
(PLOS One, 2012-06)Introduction: Abnormalities on CT imaging may contribute to the diagnosis of tuberculous meningitis (TBM). Recently, an expert consensus case definition (CCD) and set of imaging criteria for diagnosing basal meningeal ... -
The spectrum of disease in weakness and wasting of the quadriceps muscles : case reports
(Health and Medical Publishing Group -- HMPG, 1982-01)Three patients who presented with weakness and wasting of the quadriceps muscles ('quadriceps myopathy'), are reported. In each, electrophysiological and biopsy studies revealed completely different pathological processes, ... -
Task analysis in neurosciences programme design - neurological problems in general practice
(Health and Medical Publishing Group -- HMPG, 1983-02)Defining educational objectives is the key to achieving the goal of professional competence in students. The technique of task analysis was selected to determine components of competence in clinical neurology appropriate ... -
Standards for the assessment of visual evoked potentials in an ethnically heterogeneous adult population
(Health and Medical Publishing Group -- HMPG, 1985-02)Visual evoked potentials (VEPs) were recorded by chequerboard pattern-reversal stimulation in 276 normal adult subjects aged 15-73 years. The sample comprised comparable white, coloured and black groups of both sexes. ... -
EMG/ENG services rendered by clinical neurophysiology technologists in solo practice
(Health & Medical Publishing Group, 1998)[No abstract available] -
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Use of phenobarbitone for treating childhood epilepsy in resource-poor countries
(Health & Medical Publishing Group, 2005)[No abstract available] -
Diagnostic problems of leptomeningeal lymphoma : a report of 3 cases
(Health & Medical Publishing Group, 1987)Three cases are presented in which occult lymphoreticular malignant tumour spread to the spinal and cranial subarachnoid spaces inducing a problematic neurological illness characterised by poorly localised neuralgic pain, ...
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