Research Articles (Anaesthesiology and Critical Care)

Comparison of hemoglobin measurements by 3 point-of-care devices with standard laboratory values and reliability regarding decisions for blood transfusion

Johnson, Marianne; Marwick, Peter C.; Coetzee, Johan F. (Lippincott, Williams & Wilkins, 2020-08)

BACKGROUND: We compared the accuracy of 3 point-of-care testing (POCT) devices with central laboratory measurements and the extent to which between-method disagreements could influence decisions to transfuse blood. METHODS: ...

The Critical Care Society of Southern Africa Consensus Guideline on ICU triage and rationing (ConICTri)

Joynt, G. M.; Gopalan, D. P.; Argent, A. A.; Chetty, S.; Wise, R.; Lai, V. K. W.; Hodgson, E.; Lee, A.; Joubert, I.; Mokgokong, S.; Tshukutsoane, S.; Richards, G. A.; Menezes, C.; Mathivha, R. L.; Espen, B.; Levy, B.; Asante, K.; Paruk, F. (Health and Medical Publishing Group (HMPG), 2019-08)

Background: In South Africa (SA), administrators and intensive care practitioners are faced with the challenge of resource scarcity as well as an increasing demand for intensive care unit (ICU) services. ICU services are ...

Improving perioperative pain management: a preintervention and postintervention study in 7 developing countries

Zaslansky, Ruth; Chapman, C. Richard; Baumbach, Philipp; Bytyqi, Adem; Lopes, Jose M. Castro; Chetty, Sean; Kopf, Andreas; Li, Li; Ming, Lim Ern; Olawoye, Olayinka; Parico, Jane Rizza; Soyannwo, Olaitan; Stamenkovic, Dusica; Wang, Hongwei; Meissner, Winfried (Wolters Kluwer Health, 2019-01-01)

Introduction: The burden of untreated postoperative pain is high. Objective: This study assessed feasibility of using quality improvement (QI) tools to improve management of perioperative pain in hospitals in multiple ...

Anaesthetic induction with propofol: How much? How fast? How slow? What determines anesthetic induction dose? It’s the Front-End Kinetics, Doctor!

Coetzee, J. F. (Medpharm Publications, 2019)

ENGLISH ABSTRACT: It has long been realised that linear dosing according to total body weight (TBW) results in overdosing obese patients and under-dosing small children. Injected drug doses calculated on a mg.kg-1 body ...

Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software : case report

Coetzee, E.; Gray, R.; Hollmann, C.; Enslin, N. J. M.; Coetzee, J. F. (Medpharm Publications, 2019)

ENGLISH ABSTRACT: We present an uncommon case of limited dorsal myeloschisis in a 3-month-old infant requiring repair guided by intraoperative neuromonitoring (IONM) and therefore avoidance of volatile anaesthetic agents. ...

Skin disinfection practice before skin anaesthesia, prior to neuraxial blockade : a survey of government hospital practices in South Africa

Coetzee, D. F.; Senekal, A.; Scheepers, P. A. (Medpharm Publications, 2019)

ENGLISH ABSTRACT: Infectious complications following neuraxial block, although being of low incidence, may lead to morbidity and mortality. Two common methods utilised for skin disinfection before skin anaesthesia prior ...

Induction of anaesthesia with propofol according to the adjusted ideal body mass in obese and nonobese patients : an observational study

Smith, F. J.; Jurgens, F. X.; Coetzee, J. F.; Becker, P. J. (Taylor & Francis Group, 2019)

ENGLISH ABSTRACT: Obesity changes body composition including fat free mass (FFM), regarded as the “pharmacologically active mass”. Scaling drug doses to obese patients by total body mass (TBM) results in overdose. We aimed ...

An audit of the labour epidural analgesia service at a regional hospital in Gauteng Province, South Africa

Leonard, T. G. A.; Perrie, H.; Scribante, J.; Chetty, S. (Health and Medical Publishing Group, 2018)

Background. Neuraxial analgesia in the form of a labour epidural has been shown to be the most effective analgesic strategy for the labouring mother. In developed countries, data are readily available as to the number of ...

The prevalence of chronic postmastectomy pain syndrome in female breast cancer survivors

Variawa, Muhammed Luqmaan; Scribante, Juan; Perrie, Helen; Chetty, Sean (Taylor & Francis Group, 2016)

Background: Breast cancer is one of the most common cancer diagnoses in women. Surgical treatment is indicated in most patients. Postmastectomy pain syndrome (PMPS) is a debilitating neuropathic pain syndrome that develops ...

Blood pressure measurement in obese patients : non-invasive proximal forearm versus direct intra-arterial measurements

Verkhovsky, A.; Smit, M.; Levin, A.; Coetzee, J. F. (Taylor & Francis Group, 2018)

Background: In obesity, accurate perioperative blood pressure measurement using upper arm, non-invasive blood pressure (NIBP) is technically challenging. Proximal forearm NIBP may be an acceptable substitute. Mean arterial ...

Xylocaine® 10% pump spray as topical anaesthetic for venepuncture pain

Van Straten, A.; Murray, A. A.; Levin, A. I. (Taylor & Francis Group, 2018)

Background: Cutaneous analgesia for venepuncture pain can be achieved using various topically applied local anaesthetic formulations. Xylocaine® 10% Pump Spray containing lignocaine hydrochloride and 95% ethanol is exclusively ...

Priority areas for cannabis and cannabinoid product research in South Africa

Augustine, Tanya N.; Cairns, Carel J.; Chetty, Sean; Dannatt, Lisa G.; Gravett, Nadine; Grey, Glenda; Grobler, Gerhard; Jafta, Zukiswa; Kamerman, Peter; Lopes, John; Matsabisa, Motlalepula G.; Mugabo, Pierre; Mulder, Michelle; Parry, Charles; Rataemane, Solomon; Siegfried, Nandi; Steenkamp, Vanessa; Thomas, Eileen; Van Zyl-Smit, Richard (AOSIS, 2018-06)

The legalisation of cannabis for medicinal use is a contentious space both politically and in the medical community. In 2014, the Medical Innovation Bill introduced by Mario Oriani-Ambrosini MP, aimed to shift the political ...

Professionalism in anaesthesiology practice : ethical reflection on the nature of professionalism in anaesthesiology

De Roubaix, Malcolm (Informa UK Limited, trading as Taylor & Francis Group, 2017)

Anaesthesiologists are well trained and equipped to practise a high standard of care and contribute significantly to positive perioperative outcomes. Professionalism is characterised first by expertise in the clinical ...

Obstructive sleep apnoea in pregnancy and its association with pre-eclampsia

Lintott, N. C.; Van Zyl, D. G.; Burke, J. L. (Informa UK Limited, trading as Taylor & Francis Group, 2017)

Background: Obstructive sleep apnoea (OSA) in pregnancy is associated with an increased morbidity and mortality to both mother and foetus. In the South African setting the proportion of pregnant females suffering from OSA ...

Increasing the labour epidural rate in a state hospital in South Africa : challenges and opportunities

Van Zyl, Stephanus F.; Burke, Jonathan L. (Informa UK Limited, trading as Taylor & Francis Group, 2017-11-21)

Background: A 2012 audit on labour epidural analgesia rates in Tygerberg Hospital (TBH) revealed that only 2.2% of labouring parturients received epidural analgesia. This unacceptably low number necessitated a dedicated ...

Abdominal ultrasound for diagnosing abdominal tuberculosis or disseminated tuberculosis with abdominal involvement in HIV-positive adults

Van Hoving, Daniel J.; Meintjes, Graeme; Takwoingi, Yemisi; Griesel, Rulan; Maartens, Gary; Ochodo, Eleanor A. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)

This is a protocol for a Cochrane Review (Diagnostic test accuracy). The objectives are as follows: To determine the diagnostic accuracy of abdominal ultrasound as a standalone test for detecting abdominal TB or disseminated ...