Doctoral Degrees (Chemistry and Polymer Science)

High temperature multidimensional chromatography of complex and functionalized polyolefins

Ndiripo, Anthony (Stellenbosch : Stellenbosch University, 2018., 2018-12)

ENGLISH ABSTRACT: Polyolefins like all other synthetic polymers have complex microstructures that must be understood in order to predict product performance and adjust catalyst and reactor technologies. Between synthesis ...

Development of a multiple fractionation protocol for the comprehensive analysis of low density polyethylene

Eselem Bungu, Paul Severin (Stellenbosch : Stellenbosch University, 2018-12)

ENGLISH ABSTRACT: Low density polyethylene (LDPE) is a branched synthetic thermoplastic with a complex microstructure. In addition to the broad molar mass distribution (MMD), LDPE exhibits long chain branching (LCB) and ...

Crystallisation behaviour of commercial polyethylenes: a fundamental study

Matthews, Megan Esme (Stellenbosch : Stellenbosch University, 2018-12)

ENGLISH ABSTRACT: Commercial films are generally made of polyolefins, often using a blend of two different polyolefins. Specifically, low density polyethylene (LDPE) and linear low density polyethylene (LLDPE) are blended ...

Thermal and mechanical responsiveness of some 4-substituted benzonitriles

Alimi, Lukman Olawale (Stellenbosch : Stellenbosch University, 2018-12)

ENGLISH ABSTRACT: This work is based on three publications. The first manuscript describes the large volumetric thermal expansion of an organic cocrystal over a wide range of temperature (100–300 K). The novel organic ...

Design and Synthesis of potent benzimidazolone HIV Non-nucleoside reverse transcriptase inhibitors

Pribut, Nicole (Stellenbosch : Stellenbosch University, 2018-12)

ENGLISH ABSTRACT: Since the 1980’s, HIV has plagued the population on a global scale, with millions of newly infected individuals reported every year. However, with the introduction of combination therapy, which ...

Design and development of novel irreversible GSK-3β inhibitors to address Alzheimer's disease

Hamann, Anton Ruben (Stellenbosch : Stellenbosch University, 2018-03)

ENGLISH ABSTRACT: Molecular modelling on the GSK-3β protein was carried out to identify a library of suitable electrophilic warhead containing ligands that have the necessary interactions with the binding site. Several ...

Host-guest dynamics in copper-based metal-organic frameworks

Bezuidenhout, Charl X. (Stellenbosch : Stellenbosch University, 2017-12)

ENGLISH ABSTRACT: A vast number of metal-organic framework materials (MOFs) and structures have been reported in the literature. These materials are of interest as they exhibit a wide range of remarkable properties such ...

Synthesis of fused heterocyclic aromatic compounds as potential antiplasmodial agents

Jacobs, Leon (Stellenbosch : Stellenbosch University, 2017-12)

ENGLISH ABSTRACT: 3-Methyl benzofuran antiplasmodial compounds have been described in literature and and synthesis of heterocyclic derivatives forms the basis of this project. These benzofuran compounds were synthesized ...

The Synthesis and characterization of hydrophilic gold nanoparticles via a DEN-MPC method and their evaluation as biphasic catalysts

Cloete, Jezreel (Stellenbosch : Stellenbosch University, 2017-12)

ENGLISH ABSTRACT: The synthesis of hydrophilic gold nanoparticles, by using a dendrimer template method to produce dendrimer encapsulated nanoparticles (DENs), in combination with a monolayer protected cluster (MPC) method ...

Identification of the putative urinary intraspecific recognition pheromone of the caracal caracal caracal

Hailemichael Goitom, Aron (Stellenbosch : Stellenbosch University, 2017-03)

ENGLISH ABSTRACT: Sheep husbandry makes a considerable contribution to the economy of South Africa. However, it has been pressure during the last few decades due to the rapidly growing numbers of predators such as the ...

Novel characterization of decorative coatings using field-flow fractionation and a multi-detector approach

Makan, Ashwell Craig (Stellenbosch : Stellenbosch University, 2017-03)

ENGLISH ABSTRACTION: Decorative coatings are present and fulfil and important role in all industry forms from aesthetics, construction, medicine, textiles, manufacturing, packaging and timber. The raw materials used in ...

Investigation of thiazyl radical – metalloporphyrin complexes

Van Laeren, Laura Jane (Stellenbosch : Stellenbosch University, 2017-03)

ENGLISH ABSTRACT: The aim of this project was to investigate the formation of novel dithiadiazolyl-metalloporphyrin complexes with the goal of forming complexes with interesting magnetic, conductive or redox behaviour. ...

Exploring the antimalarial mechanism of action: Adsorption of diverse inhibitors to crystalline malaria pigment (haemozoin).

Muller, Ronel (Stellenbosch : Stellenbosch University, 2017-03)

ENGLISH ABSTRACT: The crystallization of free haem (ferriprotoporphyrin IX) into haemozoin within the parasitic food vacuole is a vital detoxification process in the life cycle of the malaria parasite. Quinoline antimalarial ...

A 195Pt Nuclear magnetic resonance and molecular dynamics computer simulation study of the solvation of simple platinum (IV) chlorido complex anions in water and water-miscible solvent mixtures

Engelbrecht, Leon de Villiers (2017-03)

ENGLISH ABSTRACT: A combined 195Pt NMR spectroscopy and Molecular Dynamics (MD) computer simulation study of the solvation of the octahedral Pt(IV) complex [PtCl6]2‒ in binary mixtures of water and the fully water-miscible ...