| dc.contributor.author | Hapgood, Janet P. | |
| dc.contributor.author | Koubovec, Dominique | |
| dc.contributor.author | Louw, Ann | |
| dc.contributor.author | Africander, Donita | |
| dc.date.accessioned | 2012-02-09T14:08:36Z | |
| dc.date.issued | 2004-11 | |
| dc.identifier.citation | Hapgood, J. P., Koubovec, D. Louw, A. & Africander, D. 2004. Not all progestins are the same: implications for usage. Trends in pharmacological sciences, 25(11), 554-557, doi:10.1016/j.tips.2004.09.005 | en_ZA |
| dc.identifier.issn | 1873-3735 (online) | |
| dc.identifier.issn | 0165-6147 (print) | |
| dc.identifier.other | doi:10.1016/j.tips.2004.09.005 | |
| dc.identifier.uri | http://hdl.handle.net/10019.1/19686 | |
| dc.description | The original publication is available at www.sciencedirect.com | en_ZA |
| dc.description.abstract | Recent clinical evidence showing unexpected side-effects
of progestins used in contraception and hormone replacement
therapy has highlighted the importance of choice of
synthetic progestin. The molecularmechanisms of action
of the relatively nonspecific and most widely used
synthetic progestins, medroxyprogesterone acetate and
norethisterone, are discussed in the context of this
recent clinical evidence. Future directions involving a
more mechanism-based approach for improved therapeutics,
with greater specificity and fewer side-effects,
are discussed. | en_ZA |
| dc.format.extent | 4 p. : ill. | |
| dc.language.iso | en_ZA | en_ZA |
| dc.publisher | Elsevier | en_ZA |
| dc.subject | Progestational hormones -- Physiologcial effect | en_ZA |
| dc.subject | Progesterone -- Physiological effect | en_ZA |
| dc.subject | Contraceptives | en_ZA |
| dc.subject | Hormone replacement therapy | en_ZA |
| dc.title | Not all progestins are the same : implications for usage | en_ZA |
| dc.type | Article | en_ZA |
| dc.description.version | Publishers' Version | en_ZA |
| dc.rights.holder | Elsevier | en_ZA |
| dc.embargo.terms | 2050-12-31 | en_ZA |
| dc.embargo.lift | 2050-12-31 | |
