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Not all progestins are the same : implications for usage

dc.contributor.authorHapgood, Janet P.
dc.contributor.authorKoubovec, Dominique
dc.contributor.authorLouw, Ann
dc.contributor.authorAfricander, Donita
dc.date.accessioned2012-02-09T14:08:36Z
dc.date.issued2004-11
dc.identifier.citationHapgood, J. P., Koubovec, D. Louw, A. & Africander, D. 2004. Not all progestins are the same: implications for usage. Trends in pharmacological sciences, 25(11), 554-557, doi:10.1016/j.tips.2004.09.005en_ZA
dc.identifier.issn1873-3735 (online)
dc.identifier.issn0165-6147 (print)
dc.identifier.otherdoi:10.1016/j.tips.2004.09.005
dc.identifier.urihttp://hdl.handle.net/10019.1/19686
dc.descriptionThe original publication is available at www.sciencedirect.comen_ZA
dc.description.abstractRecent clinical evidence showing unexpected side-effects of progestins used in contraception and hormone replacement therapy has highlighted the importance of choice of synthetic progestin. The molecularmechanisms of action of the relatively nonspecific and most widely used synthetic progestins, medroxyprogesterone acetate and norethisterone, are discussed in the context of this recent clinical evidence. Future directions involving a more mechanism-based approach for improved therapeutics, with greater specificity and fewer side-effects, are discussed.en_ZA
dc.format.extent4 p. : ill.
dc.language.isoen_ZAen_ZA
dc.publisherElsevieren_ZA
dc.subjectProgestational hormones -- Physiologcial effecten_ZA
dc.subjectProgesterone -- Physiological effecten_ZA
dc.subjectContraceptivesen_ZA
dc.subjectHormone replacement therapyen_ZA
dc.titleNot all progestins are the same : implications for usageen_ZA
dc.typeArticleen_ZA
dc.description.versionPublishers' Versionen_ZA
dc.rights.holderElsevieren_ZA
dc.embargo.terms2050-12-31en_ZA
dc.embargo.lift2050-12-31


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