Bacteremia in human immunodeficiency virus-infected children in Cape Town, South Africa

Date
2011
Authors
Le Roux D.M.
Cotton M.F.
Le Roux S.M.
Whitelaw A.
Lombard C.J.
Zar H.J.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Bacteremia contributes to morbidity of HIV-infected children. In a randomized controlled trial evaluating trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis, 47 bacteremias were detected. The incidence rate of bacteremia increased in the first 3 months after starting combination antiretroviral therapy (cART), but decreased by 74% once children were established on cART for more than 3 months. Children should be prioritized for early cART. Copyright © 2011 by Lippincott Williams & Wilkins.
Description
Keywords
Africa, antiretroviral therapy, bacteremia, children, HIV, preventive therapy, trimethoprim- sulfamethoxazole
Citation
Pediatric Infectious Disease Journal
30
10
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