Department of Obstetrics and Gynaecology
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Stillbirth risk across pregnancy by size for gestational age in Western Cape Province, South Africa : application of the fetuses-at-risk approach using perinatal audit data
(South African Medical Association, 2019-11-27)Background: There is little published work on the risk of stillbirth across pregnancy for small-for-gestational-age (SGA) and large-for-gestational (LGA) pregnancies in low-resource settings. Objectives: To compare ... -
Pregnancy-related acute kidney injury in preeclampsia : risk factors and renal outcomes
(American Heart Association, 2019)ENGLISH ABSTRACT: Preeclampsia is a common cause of acute kidney injury (AKI) in low- and middle-income countries, but AKI incidence in preeclampsia, its risk factors, and renal outcomes are unknown. A prospective ... -
The efficacy of intrauterine devices for emergency contraception and beyond : a systematic review update
(Dove Medical Press, 2019)Background: The copper intrauterine device (IUD) is a very effective form of emergency contraception. The failure rate is about 0.1%. IUDs are also very cost-effective when used as long acting-reversible contraception ... -
Prepregnancy and early pregnancy calcium supplementation among women at high risk of pre-eclampsia : a multicentre, double-blind, randomised, placebo-controlled trial
(Elsevier, 2019)Background: Reducing deaths from hypertensive disorders of pregnancy is a global priority. Low dietary calcium might account for the high prevalence of pre-eclampsia and eclampsia in low-income countries. Calcium supplementation ... -
Should home-based ovulation predictor kits be offered as an additional approach for fertility management for women and couples desiring pregnancy? a systematic review and meta-analysis
(BMJ Publishing Group, 2019)ENGLISH ABSTRACT: Introduction to inform the WHO Guideline on self-care interventions, we conducted a systematic review of the impact of ovulation predictor kits (OPKs) on time-topregnancy, pregnancy, live birth, ... -
Delivery outcomes of patients with pre-eclampsia at 27 - 34 weeks’ gestation at Tygerberg Hospital, Cape Town, South Africa : a retrospective observational study
(Health & Medical Publishing Group, 2021-04-03)Background. Obstetricians are cognisant of the serious nature of hypertensive disorders in pregnancy. Despite a 17% overall reduction in maternal deaths in South Africa between 2011 and 2016, there was a 14% increase in ... -
Shock index thresholds to predict adverse outcomes in maternal hemorrhage and sepsis : a prospective cohort study
(Wiley, 2019)Introduction: Shock index (SI) is a predictor of hemodynamic compromise in obstetric patients. The SI threshold for action is not well understood. We aimed to evaluate SI thresholds as predictors of outcomes in obstetric ... -
Prenatal diagnosis and outcomes of congenital Lower Urinary Tract Obstruction (LUTO) at Tygerberg Hospital Fetal Medicine Unit: an audit of 12 years
(Stellenbosch : Stellenbosch University, 2015-12)ENGLISH ABSTRACT: Objective: To determine the frequency, etiology, survival and associated morbidity of prenatally detected Lower Urinary Tract Obstruction (LUTO) to predict outcome and guide prenatal counselling and ... -
Maternal and perinatal adverse outcomes in women with pre-eclampsia cared for at facility-level in South Africa : a prospective cohort study
(Edinburgh University Global Health Society, 2018)Background: Hypertensive disorders of pregnancy contribute to 14% of all maternal deaths, the majority of which occur in low- and middle-income countries. The aim of the study was to describe the maternal and perinatal clinical ... -
Time-lapse analysis and morphokinetic evaluation of fresh vs. vitrified/warmed oocytes, including donor and explorative sibling oocyte cycles
(Stellenbosch : Stellenbosch University., 2020-03)ENGLISH ABSTRACT: BACKGROUND: Infertility is defined as a disorder of the reproductive system whereby there is failure to achieve a clinical pregnancy after 12 months or more of regular unprotected sexual intercourse. The ... -
Report on the live birth rates and neonatal outcomes of ART patients at Aevitas Fertility Clinic : implications of a Frozen Embryo Transfer (FET) program
(Stellenbosch : Stellenbosch University, 2020-03)ENGLISH ABSTRACT : Background: The practice of Assisted Reproductive Technologies (ARTs) has become quite commercial in the last decade or two, since an increasing number of couple’s face fertility challenges and nevertheless ... -
Major obstetric haemorrhage in Metro East, Cape Town, South Africa : a population-based cohort study using the maternal near-miss approach
(BMC (part of Springer Nature), 2020-01-06)Background: Major obstetric haemorrhage is a leading cause of maternal mortality and accounts for one-third of maternal deaths in of Africa. This study aimed to assess the population-based incidence, causes, management ... -
Uterine carcinosarcoma: A 10-Year single institution experience
(Stellenbosch : Stellenbosch University, 2019-12)Objective: This study aimed to determine 5-year progression-free and overall survival in patients with uterine carcinosarcoma, to determine clinical and surgical-pathologic features, to recognize patterns of recurrence and ... -
Eyeball (Office) urodynamics: is there value to predict hidden (Occult) stress urinary incontinence with sims speculum reduction in patients with pelvic organ prolapse? – a retrospective descriptive study
(Stellenbosch : Stellenbosch University, 2019-12)Introduction: Occult stress urinary incontinence (OSUI) is an accepted predictor of postoperative stress urinary incontinence (POSUI) in stress continent women with pelvic organ prolapse (POP)(1). De novo stress urinary ... -
'Reds flags' in antenatal care : fetal movements and fetal growth
(Health & Medical Publishing Group, 2018)Poor fetal growth in late pregnancy is a very common cause of stillbirth or fetal distress during labour. It is associated with reduced fetal movements, which can be detected by the mother antenatally. A simple management ... -
Failure to perform assisted deliveries is resulting in an increased neonatal and maternal morbidity and mortality : an expert opinion
(Health & Medical Publishing Group, 2018)The need to perform assisted vaginal delivery (AVD) has been regarded as self-evident. In high-income countries, rates of AVD range between 5% and 20% of all births. In South Africa, the rate of AVD is only 1%. This has ... -
Avoiding paternalism but not moral perplexity
(Health & Medical Publishing Group, 2018)Maternal autonomy has replaced medical paternalism, but conflicts between beneficence and autonomy persist. -
Reducing neonatal deaths in South Africa : progress and challenges
(Health & Medical Publishing Group, 2018)Although current levels of the neonatal mortality rate (NMR) are within reach of the Sustainable Development Goal (SDG) target of 12 per 1 000 live births, the absolute number of deaths is unacceptably high for a ... -
The impact of HIV status on staging, treatment and outcomes in locally advanced cervical carcinoma
(Stellenbosch : Stellenbosch University, 2019-12)ENGLISH ABSTRACT: Cervical carcinoma is one of the most frequently diagnosed malignancies in women in many countries in sub-Saharan Africa, including South Africa. In sub-Saharan Africa, among women without HIV the ... -
Management of epithelial ovarian cancer at a tertiary centre in South Africa: a retrospective evaluation of early recurrence and contributory factors
(Stellenbosch : Stellenbosch University, 2019-12)Introduction. Epithelial ovarian cancer is associated with high recurrence rates and poor survival, especially if the disease is advanced, surgery sub-optimal, and or has high-grade histology. However, there is a paucity ...
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