Department of Obstetrics and Gynaecology
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Recent Submissions
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The costs and cost effectiveness of providing second-trimester medical and surgical safe abortion services in Western Cape Province, South Africa
(Public Library of Science, 2018-06-28)Background: In South Africa, access to second-trimester abortion services, which are generally performed using medical induction with misoprostol alone, is challenging for many women. We aimed to estimate the costs and ... -
Combined evaluation of sexually transmitted infections in HIV-infected pregnant women and infant HIV transmission
(PLOS, 2018-01-05)Background: Sexually transmitted infections (STIs) including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Treponema pallidum (TP), and cytomegalovirus (CMV) may lead to adverse pregnancy and infant outcomes. The ... -
Longterm follow-up of anti-müllerian hormone levels in patients who had surgery for endometrioma
(Stellenbosch : Stellenbosch University, 2019-04)Introduction: Endometriosis is highly prevalent among women of reproductive age increasing up to 50% in those presenting with infertility. Ovarian endometriosis, known as endometriomas, is found in up to 44% of women ... -
Bone involvement in patients with cervical carcinoma – a single institution cohort study
(Stellenbosch : Stellenbosch University, 2019-04)Introduction Bony metastases in cervical carcinoma are rare, occurring on average in 4.6% of patients. Autopsy studies indicate that it is underdiagnosed. It is important to recognise bony infiltration as palliative ... -
Effect of human male patient diagnosis on syngamy timing and blastulation using time-lapse technology
(Stellenbosch : Stellenbosch University, 2019-04)BACKGROUND: Improving embryo selection for embryo transfer is essential in Assisted Reproductive Technologies (ART), especially in single embryo transfer settings to reduce multiple birth rate. Current selection methods ... -
Point-of-care screening for hepatitis B virus infection in pregnant women at an antenatal clinic : a South African experience
(Public Library of Science, 2017)Background & aims: Elimination of HIV and syphilis mother-to-child transmission (MTCT) has received much attention but little consideration has been given to the possibility of elimination of HBV MTCT. In sub-Saharan ... -
Insertion of intrauterine devices after cesarean section : a systematic review update
(Dove Medical Press, 2017-04-18)Background: Women who undergo a cesarean section (CS) are in a unique position to receive the intrauterine contraceptive device (IUD). They may also want to use the IUD as a long-acting reversible contraceptive method ... -
The Preeclampsia intervention with Esomeprazole (PIE) trial: A double blind, randomised, placebo-controlled trial to treat early onset severe preeclampsia
(Stellenbosch : Stellenbosch University, 2019-04)ENGLISH ABSTRACT: This body of work addresses the clinical dilemma posed by preterm preeclampsia. Firstly, we tested a potential therapeutic (esomeprazole) for the treatment of early preterm preeclampsia in a double-blind ... -
Standardized outcome measures for pregnancy and childbirth, an ICHOM proposal
(BMC (part of Springer Nature), 2018-12-11)Background: Value-based health care aims to optimize the balance of patient outcomes and health care costs. To improve value in perinatal care using this strategy, standard outcomes must first be defined. The objective ... -
Exploring the feasibility of using mobile phones to improve the management of clients with cervical cancer precursor lesions
(BMC (part of Springer Nature), 2019-01-07)Background: Cancer screening programs hold much potential for reducing the cervical cancer disease burden in developing countries. The aim of this study was to determine the feasibility of mobile health (mHealth) ... -
Bereaved mothers' attitudes regarding autopsy of their stillborn baby
(Health and Medical Publishing Group, 2017-12)Background. Here we present additional information from the Safe Passage Study, where the effect of alcohol exposure during pregnancy on sudden infant death syndrome and stillbirth was investigated. Objective. To explore ... -
A Descriptive study of low risk women presenting in suspected preterm labour at Tygerberg hospital
(Stellenbosch : Stellenbosch University, 2018-12)Introduction: Preterm birth refers to delivery before 37 completed weeks’ gestation and is often, but not always, preceded by spontaneous preterm labour. Prematurity due to preterm birth is the leading cause of direct ... -
A prospective population-based study of preterm pre-labour rupture of membranes between 24 and 34 weeks of gestation in Cape Town Metro East: measuring protocol intervention fidelity and clinical outcome
(Stellenbosch : Stellenbosch University, 2018-12)BACKGROUND: Preterm premature rupture of membranes (PPROM) complicates 2 to 3% of pregnancies and is associated with significant neonatal mortality and morbidity. Intrauterine infection is the most common cause of PPROM, ... -
Factors related to the late presentation of women with vulvar cancer
(Stellenbosch : Stellenbosch University, 2018-12)Background Vulva cancer is increasing in incidence and becoming more prevalent amongst younger women. Over 50% of patients present with advanced stage disease at Tygerberg Hospital. The prognosis for late stage vulvar ... -
The contextual quality of life of women with cervical cancer in the Western Cape, South Africa.
(Stellenbosch : Stellenbosch University, 2018-12)ENGLISH ABSTRACT: Please refer to full text for abstract -
Vulvar cancer is not a disease of the elderly : treatment and outcome at a tertiary referral centre in South Africa
(Health & Medical Publishing Group, 2017)Background. An increase in vulvar cancer in young women is attributed to infection with oncogenic human papillomavirus (HPV). South Africa (SA) has a high prevalence of HPV, and it was therefore hypothesised that women ... -
Tranexamic acid for preventing postpartum haemorrhage
(Cochrane, 2015-06-16)Background: Postpartum haemorrhage (PPH) is a common and potentially life-threatening complication of labour. Several options for preventing PPH are available, but further advances in this field are important, especially ... -
Interventions for helping to turn term breech babies to head first presentation when using external cephalic version
(Cochrane, 2015-02-12)Background: Breech presentation is associated with increased complications. Turning a breech baby to head first presentation using external cephalic version (ECV) attempts to reduce the chances of breech presentation at ... -
Women's experiences with cervical cancer screening in a colposcopy referral clinic in Cape Town, South Africa: a qualitative analysis
(BMJ Publishing Group, 2017-1)Objective: The aim of this study was to explore and understand women’s experience with cervical cancer screening and with the referral pathways for abnormal Papanicolau (Pap) smears. Design and setting: Focus group ... -
Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term
(John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)Background: Hypertensive disorders in pregnancy are significant contributors to maternal and perinatal morbidity and mortality. These disorders include well‐controlled chronic hypertension, gestational hypertension ...
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