Department of Medicine
Sub-communities within this community
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Cardiology [67]
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Clinical Pharmacology [106]
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Dermatology [10]
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Endocrinology [9]
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Gastroenterology [5]
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General Medicine [43]
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Infectious Diseases [36]
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Nephrology [36]
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Neurology [15]
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Pulmonology [47]
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Rheumatology [6]
Recent Submissions
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A cross-sectional study to investigate the knowledge, attitudes, and current practices of pharmacovigilance, among medical doctors and pharmacists in South Africa
(Stellenbosch : Stellenbosch University, 2021-12)Background: Pharmacovigilance pertains to activities aimed at monitoring medicines for related safety concerns, thereby ensuring patient safety and wellbeing. The primary method of pharmacovigilance is spontaneous reporting ... -
Comparison of antiretroviral therapy adherence among HIV-infected older adults with younger adults in Africa : systematic review and meta-analysis
(Springer, 2019)ENGLISH ABSTRACT: As access to antiretroviral treatment in low- and middle-income countries improves, the number of older adults (aged ≥ 50 years) living with HIV is increasing. This study compares the adherence to ... -
Chronic kidney disease for the primary care clinician
(South African Academy of Family Physicians, 2019-10-28)ENGLISH ABSTRACT: An epidemic of chronic kidney disease (CKD) is being experienced in South Africa. This is driven by a heavy burden of infections, non-communicable diseases, pregnancy-related diseases and injuries. The ... -
The significance of non-occupational asbestos exposure in women with mesothelioma
(Wiley Open Access, 2019-01)ENGLISH ABSTRACT: Malignant mesothelioma is a rare and aggressive pleural or peritoneal tumour almost always caused by exposure to asbestos fibres. Exposure to asbestos can cause malignant mesothelioma 30–40 years after ... -
Multiple introductions of mycobacterium tuberculosis lineage 2–Beijing into Africa over centuries
(Frontiers Media, 2019)ENGLISH ABSTRACT: The Lineage 2–Beijing (L2–Beijing) sub-lineage of Mycobacterium tuberculosis has received much attention due to its high virulence, fast disease progression, and association with antibiotic resistance. ... -
Relationship between chest radiographic characteristics, sputum bacterial load, and treatment outcomes in patients with extensively drug-resistant tuberculosis
(Elsevier, 2019)Background: Data about the relationship between chest radiographs and sputum bacillary load, with treatment outcomes, in patients with extensively drug-resistant tuberculosis (XDR-TB) from HIV/TB endemic settings are ... -
Managing and preventing vascular catheter infections : a position paper of the international society for infectious diseases
(Elsevier, 2019)ENGLISH ABSTRACT: A panel of experts was convened by the International Society for Infectious Diseases (ISID) to overview recommendations on managing and preventing vascular catheter infections, specifically for the prevention ... -
Global infection prevention gaps, needs, and utilization of educational resources: A cross-sectional assessment by the International Society for Infectious Diseases
(Elsevier, 2019)Objective: The Guide to Infection Control in the Hospital (Guide) is an open access resource produced by the International Society for Infectious Diseases (ISID) to assist in the prevention of infection acquisition ... -
The prevalence and risk factors for diabetes mellitus in healthcare workers at Tygerberg hospital, Cape Town, South Africa : a retrospective study
(MedPharm Publications, 2019)Objectives: To assess the contribution of traditional and modifiable risk factors to the overall risk and prevalence of type 2 diabetes mellitus (T2DM) amongst health workers (HWs) in the public sector. Design: A ... -
Balancing the risks to individual and society : a systematic review and synthesis of qualitative research on antibiotic prescribing behaviour in hospitals
(Elsevier, 2019)Background: Antimicrobial resistance is a global health threat, partly driven by inappropriate antibiotic prescriptions for acute medical patients in hospitals. Aim: To provide a systematic review of qualitative research ... -
Recommendations for lung cancer screening in Southern Africa
(AME Publishing, 2019-07-09)ENGLISH ABSTRACT: Lung cancer remains the leading cause of cancer-related deaths in southern Africa. Early trials of chest radiograph-based screening in males at high risk for lung cancer found no mortality benefit of a ... -
Management of chronic obstructive pulmonary disease—A position statement of the South African Thoracic Society : 2019 update
(AME Publishing, 2019-10-06)ENGLISH ABSTRACT: Chronic obstructive pulmonary disease (COPD) is a significant cause of death and disability in both developed and developing countries. It is increasing in frequency and demands increasing utilisation of ... -
Increasing access to integrated ESKD care as part of universal health coverage
(Elsevier, 2019)ENGLISH ABSTRACT: The global nephrology community recognizes the need for a cohesive strategy to address the growing problem of end-stage kidney disease (ESKD). In March 2018, the International Society of Nephrology hosted ... -
Emerging differences between Huntington's disease-like 2 and Huntington's disease : a comparison using MRI brain volumetry
(Elsevier, 2019)ENGLISH ABSTRACT: Huntington's Disease-Like 2 (HDL2), caused by a CTG/CAG expansion in JPH3 on chromosome 16q24, is the most common Huntington's Disease (HD) phenocopy in populations with African ancestry. Qualitatively, ... -
Trends in the nephrologist workforce in South Africa (2002–2017) and forecasting for 2030
(Public Library of Science, 2021)Background: The growing global health burden of kidney disease is substantial and the nephrology workforce is critical to managing it. There are concerns that the nephrology workforce appears to be shrinking in many ... -
An endotracheal plasmablastic lymphoma
(S. Karger AG, Basel, 2019)ENGLISH ABSTRACT: We describe an exceptionally rare case of a male patient with newly diagnosed advanced human immunodeficiency virus (HIV) infection, who presented with a plasmablastic lymphoma involving the right maxillary ... -
An overview of analgesics : NSAIDs, paracetamol, and topical analgesics Part 1
(Taylor and Francis, 2019)ENGLISH ABSTRACT: Pain is a complex and unique experience. It encompasses several pathways, involving nociceptive signal generation (transduction) and propagation (transmission), as well as perception and modulation of ... -
An overview of analgesics - anticonvulsants, antidepressants, and other medications (Part 3)
(AOSIS, 2019)ENGLISH ABSTRACT: Pain is classified by various descriptions. Chronic pain has been described as being neuropathic (due to nervous system lesions), nociceptive (due to tissue damage), or mixed (a combination of neuropathic ... -
An overview of analgesics : opioids, tramadol, and tapentadol (Part 2)
(AOSIS, 2019)ENGLISH ABSTRACT: Pain can be caused by several mechanisms, and the development of chronic pain (also known as pain chronification) is a complex and often unpredictable process. Opioids, tramadol, and tapentadol provide ... -
Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe
(BMC, 2021-05-24)Background: Drug potency is a pharmacological parameter defining dose or concentration of drug required to obtain 50% of the drug’s maximal effect. Pharmacokinetic-pharmacodynamic modelling and simulation allows estimation ...
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