Department of Medicine
Sub-communities within this community
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Cardiology [61]
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Dermatology [8]
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Endocrinology [8]
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Gastroenterology [4]
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General Medicine [40]
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Infectious Diseases [26]
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Nephrology [32]
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Neurology [14]
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Pulmonology [41]
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Rheumatology [6]
Recent Submissions
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Exploring the factors that affect new graduates’ transition from students to health professionals : a systematic integrative review protocol
(BMJ Publishing Group, 2020-05-15)Introduction: To become a competent health professional, the nature of new graduates’ transition plays a fundamental role. The systematic integrative review will aim to identify the existing literature pertaining to the ... -
In vitro assessment of the interaction potential of ocimum basilicum (L.) extracts on CYP2B6, 3A4, and rifampicin metabolism
(Frontiers Media, 2020-04-30)ENGLISH ABSTRACT: Ocimum basilicum L. or basilicum is a common culinary herb, used as a traditional medicine for various medical conditions including HIV/AIDS and tuberculosis, in Africa. The objective of this study was ... -
Flower cells in patient with HTLV1 associated adult T-cell leukaemia/lymphoma
(Oxford University Press, 2020-10-04)ENGLISH ABSTRACT: No abstract available. -
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir : a study of HIV-infected Zimbabwean adolescents
(BMC, 2020-08-03)Background: Adolescents experience higher levels of non-adherence to HIV treatment. Drug concentration in hair promises to be reliable for assessing exposure to antiretroviral (ARV) drugs. Pharmacokinetic modelling can ... -
Staff testing for COVID-19 via an online pre-registration form
(medRxiv, 2020)Background: Healthcare workers are at increased risk of contracting SARS-CoV-2 and potentially causing institutional outbreaks. Staff testing is critical in identifying and isolating infected individuals while also reducing ... -
Accelerating clinical evaluation of repurposed combination therapies for COVID-19
(American Society of Tropical Medicine and Hygiene, 2020-08-21)As the global COVID-19 pandemic continues, unabated and clinical trials demonstrate limited effective pharmaceutical interventions, there is a pressing need to accelerate treatment evaluations. Among options for accelerated ... -
Artemisia Spp. derivatives for COVID-19 treatment : anecdotal use, political hype, treatment potential, challenges, and road map to randomized clinical trials
(American Society of Tropical Medicine and Hygiene, 2020)The world is currently facing a novel COVID-19 pandemic caused by SARS-CoV-2 that, as of July 12, 2020, has caused a reported 12,322,395 cases and 556,335 deaths. To date, only two treatments, remdesivir and dexamethasone, ... -
High HIV prevalence in an early cohort of hospital admissions with COVID-19 in Cape Town, South Africa
(Health & Medical Publishing Group, 2020)Background. South Africa (SA) has a high prevalence of HIV and tuberculosis. Cape Town was the SA metropole most affected in the early stages of the COVID-19 pandemic. Early observational data from Africa may provide ... -
Transition from restrictive to obstructive lung function impairment during treatment and follow-up of active tuberculosis
(Dove Medical Press, 2020)Background: Pulmonary tuberculosis (PTB) is associated with many forms of chronic lung disease including the development of chronic airflow obstruction (AFO). However, the nature, evolution and mechanisms responsible for ... -
Screening strategies for adults with type 2 diabetes mellitus : a systematic review protocol
(BMC (part of Springer Nature), 2020-07-13)Background: There is limited evidence on whether screening for type 2 diabetes mellitus affects health outcomes. A recent systematic review of randomised clinical trials found only one trial that met their inclusion ... -
Pattern of renal amyloidosis in South Africa
(BMC (part of Springer Nature), 2019)Background: Kidney disease is a serious manifestation of systemic amyloidosis and a major cause of morbidity and mortality. Tuberculosis (TB) occurs up to 27 times more commonly in human immunodeficiency virus (HIV) ... -
Human resources for nephrology in South Africa : a mixed-methods study
(Public Library of Science, 2020-02-13)Introduction: The global nephrology workforce is shrinking and, in many countries, is unable to meet healthcare needs. Accurate data pertaining to human resources in nephrology in South Africa is lacking. This data is ... -
Predictors of 1-year survival in South African transcatheter aortic valve implant candidates
(Health & Medical Publishing Group, 2020)Background. Transcatheter aortic valve implantation (TAVI) has undergone rapid expansion internationally over the past 15 years. In view of resource constraints in developing countries, a major challenge in applying this ... -
The global initiative for asthma 2019 recommendation for mild asthma – a critique
(AOSIS, 2020-03-05)Recognising that mild asthmatics are at risk of exacerbations and mortality, the Global Initiative for Asthma (GINA) issued an updated strategy in 2019. This was premised on two studies culminating in their recommendation ... -
A massive pericardial effusion in South Africa is not always due to tuberculosis
(South African Heart Association, 2020)South Africa (SA) has a high incidence of tuberculosis. Medical conditions mimicking tuberculosis often result in erroneous treatment with antitubercular therapy (ATT) before a definitive diagnosis is made. We report on 2 ... -
Sporotrichosis in renal transplant patients : two case reports and a review of the literature
(BMC (part of Springer Nature), 2020-06-26)Introduction: Sporotrichosis is a rare fungal infection in transplant patients; among these patients, it occurs mostly in renal transplant patients. Sporothrix schenkii is the primary pathogen responsible. A high index ... -
Points to consider in cardiovascular disease risk management among patients with rheumatoid arthritis living in South Africa, an unequal middle income country
(BMC (part of Springer Nature), 2020-06-16)Background: It is plausible that optimal cardiovascular disease (CVD) risk management differs in patients with rheumatoid arthritis (RA) from low or middle income compared to high income populations. This study aimed ... -
Mobile health technology for enhancing the COVID-19 response in Africa : a potential game changer?
(American Society of Tropical Medicine and Hygiene, 2020)The WHO Africa Region is experiencing an increase in the number of novel COVID-19 cases. As of May 20, 2020, 63,521 cases with 1,796 deaths (2.8% case fatality) have been reported from 45 countries.1 Although these ... -
COVID-19 in Africa : care and protection for frontline healthcare workers
(BioMed Central, 2020)Medical staff caring for COVID-19 patients face mental stress, physical exhaustion, separation from families, stigma, and the pain of losing patients and colleagues. Many of them have acquired SARS-CoV-2 and some have ... -
The utility of high-flow nasal cannula oxygen therapy in the management of respiratory failure secondary to COVID-19 pneumonia
(Health & Medical Publishing Group, 2020-05-07)COVID-19 is a potentially fatal infection caused by SARS-CoV-2.[1] As of 4 May 2020, more than 6 000 cases had been confirmed in South Africa (SA) with numbers rising steadily, a situation that will place a major strain ...
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