Faculty of Medicine and Health Sciences
The vision of the Faculty of Medicine and Health Sciences is to be a dynamic, people-centred and inclusive environment, internationally recognised for its excellence in research, education and clinical training in medicine and health sciences, and for the contribution it makes to improving health and health care in South Africa, the African continent and beyond.
This faculty was known as the Faculty of Health Sciences until 30 April 2012.
Sub-communities within this community
Recent Submissions
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A Validated stable HPLC method for the simultaneous determination of rifampicin and 25-O-desacetyl rifampicin – evaluation of in vitro metabolism
(Akademiai Kiado, 2017)A simple, efficient, and stable high-performance liquid chromatography (HPLC) separation method for a combination of rifampicin (RIF), its major metabolite 25-O-desacetyl rifampicin (25ODESRIF), and neostigmine (NEO) was ...
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Paediatric antimicrobial use at a South African hospital
(Elsevier, 2018)Background: Data on antimicrobial use among hospitalized children in Africa are very limited due to the absence of electronic prescription tracking. Methods: This study evaluated antimicrobial consumption rates, the ...
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Lipoatrophy/lipohypertrophy outcomes after antiretroviral therapy switch in children in the UK/Ireland
(Public Library of Science, 2017)Background: Following widespread use of stavudine, a thymidine analogue, in antiretroviral therapy (ART) over the past three decades, up to a third of children developed lipoatrophy (LA) and/or lipohypertrophy (LH). ...
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Rutin as a potent antioxidant : implications for neurodegenerative disorders
(Hindawi, 2018)A wide range of neurodegenerative diseases (NDs), including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and prion diseases, share common mechanisms such as neuronal loss, apoptosis, mitochondrial ...
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Sexual assault survivors’ perspectives on clinical follow-up in the Eden District, South Africa : a qualitative study
(AOSIS Publishing, 2018)Background: Although effective follow-up of sexual assault survivors is linked to optimal recovery, attendance at follow-up consultations is poor. It is therefore essential that health care providers maximise the benefit ...
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The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis
(BioMed Central, 2018-07-12)Background: Three low molecular weight thiols are synthesized by Mycobacterium tuberculosis (M.tb), namely ergothioneine (ERG), mycothiol (MSH) and gamma-glutamylcysteine (GGC). They are able to counteract reactive oxygen ...
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Toxicity associated with tuberculosis chemotherapy in the REMoxTB study
(BioMed Central, 2018-07-11)Background: The incidence and severity of tuberculosis chemotherapy toxicity is poorly characterised. We used data available from patients in the REMoxTB trial to provide an assessment of the risks associated with the ...
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Criteria for enhancing mucus transport : a systematic scoping review
(BioMed Central, 2018-07-06)Background: Uncertainty exists regarding the physiological basis of physiotherapy strategies to facilitate mucus clearance. The aim of this review was to describe the physiological factors and intrinsic conditions that ...
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Describing the categories of people that contribute to an Emergency Centre crowd at Khayelitsha hospital, Western Cape, South Africa
(Elsevier, 2017-06)Introduction: Emergency Centre (EC) crowding has globally been recognised to adversely affect patients, staff and visitors. Anecdotally, local ECs are perceived to be fairly crowded, however, not much is known about the ...
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A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images
(Springer Open, 2018-06-25)Background: There is a growing interest in the use of 18F-FDG PET-CT to monitor tuberculosis (TB) treatment response. However, TB causes complex and widespread pathology, which is challenging to segment and quantify in a ...
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The socioeconomic profile of alcohol-attributable mortality in South Africa : a modelling study
(BioMed Central, 2018-06-25)Background: Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher risk of dying prematurely. Alcohol consumption has been shown to be a factor ...
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Integration of care for hypertension and diabetes : a scoping review assessing the evidence from systematic reviews and evaluating reporting
(BioMed Central, 2018-06-20)Background: With the rise in premature mortality rate from non-communicable disease (NCD), there is a need for evidence-based interventions. We evaluated existing systematic reviews on effectiveness of integration of ...
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Whole-body vibration exercise improves functional parameters in patients with osteogenesis imperfect : a systematic review with a suitable approach
(African Traditional Herbal Medicine Supporters Initiative, 2017)Background: Patients with osteogenesis imperfecta (OI) have abnormal bone modelling and resorption. The bone tissue adaptation and responsivity to dynamic and mechanical loading may be of therapeutic use under ...
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Whole-body vibration exercise is well tolerated in patients with duchenne muscular dystrophy : a systematic review
(African Traditional Herbal Medicine Supporters Initiative, 2017)Background: Duchenne muscular dystrophy (DMD) is caused by a defective gene located on the X-chromosome, responsible for the production of the dystrophin protein. Complications in the musculoskeletal system have ...
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Poor adherence to Tranexamic acid guidelines for adult, injured patients presenting to a district, public, South African hospital
(Elsevier, 2017-06)Introduction: In South Africa’s high injury prevalent setting, it is imperative that injury mortality is kept to a minimum. The CRASH-2 trial showed that Tranexamic acid (TXA) in severe injury reduces mortality. Implementation ...
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Percutaneous coronary intervention still not accessible for many South Africans
(Elsevier, 2017-09)Introduction: The incidence of myocardial infarction is rising in Sub-Saharan Africa. In order to reduce mortality, timely reperfusion by percutaneous coronary intervention (PCI) or thrombolysis followed by PCI is required. ...
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South-South Cooperation in health professional education : a literature review
(Health and Medical Publishing Group, 2017)In the literature on the evolution of funding approaches there is criticism of traditional funding strategies and the promotion of inclusive models, such as South-South Cooperation (SSC) and triangular models. The latter ...
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Self-directed learning : status of final-year students and perceptions of selected faculty leadership in a Nigerian medical school – a mixed analysis study
(Health and Medical Publishing Group, 2017)Background. Self-directed learning (SDL) is the essential mechanism of lifelong learning, which, in turn, is required for medical professionals to maintain competency because of advancing technology and constantly evolving ...
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Occupational therapy students’ perspectives on the core competencies of graduates to practise in the field of neurology
(Health and Medical Publishing Group, 2017)Background. The South African (SA) health system is characterised by limited resources, high bed turnover rates and a high therapist-to-patient ratio. Patients with neurological dysfunction form a large majority of the ...
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Self-regulated learning : a key learning effect of feedback in a problem-based learning context
(Health and Medical Publishing Group, 2017)Background. Problem-based learning (PBL) has been adopted across many health professions training institutions. Small-group student tutorials are a major component of PBL. Facilitator feedback during a tutorial is a key ...
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Health sciences students’ contribution to human resources for health strategy : a rural health careers day for grade 12 learners in the North West Province of South Africa
(Health and Medical Publishing Group, 2017)No abstract
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Case mix of patients managed in the resuscitation area of a district-level public hospital in Cape Town
(Elsevier, 2017-03)Introduction: At the core of the district health system is the emergency centre, for many the entry point into the healthcare system. Limited data is available on the patient population served by district-level emergency ...
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African emergency care providers attitudes and practices towards research
(Elsevier, 2017-03)Introduction: Emergency care research in Africa is not on par with other world regions. The study aimed to assess the perceptions and practices towards research among current emergency care providers in Africa. Methods: ...
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A description of pharmacological analgesia administration by public sector advanced life support paramedics in the City of Cape Town
(Elsevier, 2017-03)Introduction: Emergency Medical Services are ideally placed to provide relief of acute pain and discomfort. The objectives of this study were to describe pre-hospital pain management practices by Emergency Medical Services ...
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A literature review on work transitioning of youth with disabilities into competitive employment
(AOSIS publishing, 2017-08)Background: The marginalisation of youth with disabilities from employment opportunities is evident from literature in as far as they form part of the larger groups ‘people with disabilities’ and ‘youth’. A focused view ...
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A peer evaluation of the community-based education programme for medical students at the University of Zimbabwe College of Health Sciences: a southern African Medical Education Partnership Initiative (MEPI) collaboration
(Health and Medical Publishing Group, 2017)Background. The University of Zimbabwe College of Health Sciences (UZCHS), Harare, which has a long tradition of community-based education (CBE), has not been evaluated since 1991. An innovative approach was used to evaluate ...
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Compliance with the consumption of iron and folate supplements by pregnant women in Mafikeng local municipality, North West province, South Africa
(Makerere University, Faculty of Medicine, 2017-11)Compliance with the consumption of iron and folate supplements by pregnant women in Mafikeng local municipality, North West province, South Africa Xikombiso Mbhenyane, Matodzi Cherane Abstract Background: Anaemia ...
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Anti-mycobacterium tuberculosis activity of polyherbal medicines used for the treatment of tuberculosis in Eastern Cape, South Africa
(Makerere University, Faculty of Medicine, 2017)Background: The emergence of drug-resistant strains of Mycobacterium tuberculosis has become a global public health problem. Polyherbal medicines offer great hope for developing alternative drugs for the treatment of ...
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Are women with history of pre-eclampsia starting a new pregnancy in good nutritional status in South Africa and Zimbabwe?
(BioMed Central, 2018-06-15)Background: Maternal nutritional status before and during pregnancy is an important contributor to pregnancy outcomes and early child health. The aim of this study was to describe the preconceptional nutritional status ...
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An ultrasonographic analysis of the activation patterns of abdominal muscles in children with spastic type cerebral palsy and in typically developing individuals : a comparative study
(BioMed Central, 2018-06-05)Background: Abdominal muscles have stiffer appearance in individuals with spastic type cerebral palsy (STCP) than in their typically developing (TD) peers. This apparent stiffness has been implicated in pelvic instability, ...
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