Behaviour profiles after tuberculous meningitis

Wait J.W.
Schoeman J.F.
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The purpose of the study was to investigate child behaviour in children who recovered from tuberculous meningitis (TBM) and to compare behaviour profiles of stage II and stage III patients. The mean age of the cohort of 74 children at the time of evaluation was 10 years and 7 months. At follow-up all patients underwent a thorough neurological examination and a psychometric test battery, which included intellectual assessment and evaluation of behaviour by means of the CBCL/6-18. Results indicated elevated mean scores (T > 60) on CBCL/6-18 scales which measure problems with anxiety, depression, attention, social relationships, disruptive and rule-breaking behaviour. Mean CBCL scores of stage III patients were significantly higher than the mean scores of stage II patients on scales which measure social problems, disruptive and rule-breaking behaviour. In addition, problems with conduct, attention, attention-deficit/hyperactivity problems, affective problems as well as the total problem scores were more pronounced in the patients with stage III TBM. We conclude that general behavioural disinhibitions as well as internalized emotional disorder probably are long-term complications in more than 10%; of the survivors of TBM. © The Author [2009]. Published by Oxford University Press. All rights reserved.
affect, anxiety disorder, article, attention, attention deficit disorder, attention disturbance, child, child behavior, cohort analysis, conduct disorder, depression, disruptive behavior, emotional disorder, female, follow up, human, intellect, major clinical study, male, psychometry, social aspect, tuberculous meningitis, adolescent, behavior disorder, classification, hospitalization, infant, mental disease, preschool child, psychological aspect, questionnaire, social behavior, socioeconomics, survivor, treatment outcome, tuberculostatic agent, Adolescent, Antitubercular Agents, Child, Child Behavior Disorders, Child, Preschool, Cohort Studies, Female, Follow-Up Studies, Humans, Infant, Male, Mental Disorders, Questionnaires, Severity of Illness Index, Social Behavior, Socioeconomic Factors, Survivors, Treatment Outcome, Tuberculosis, Meningeal
Journal of Tropical Pediatrics