Research Articles (Obstetrics and Gynaecology)

The costs and cost effectiveness of providing second-trimester medical and surgical safe abortion services in Western Cape Province, South Africa

Lince-Deroche, Naomi; Constant, Deborah; Harries, Jane; Kluge, Judith; Blanchard, Kelly; Sinanovic, Edina; Grossman, Daniel (Public Library of Science, 2018-06-28)

Background: In South Africa, access to second-trimester abortion services, which are generally performed using medical induction with misoprostol alone, is challenging for many women. We aimed to estimate the costs and ...

Combined evaluation of sexually transmitted infections in HIV-infected pregnant women and infant HIV transmission

Adachi, Kristina; Xu, Jiahong; Yeganeh, Nava; Camarca, Margaret; Morgado, Mariza G.; Watts, D. Heather; Mofenson, Lynne M.; Veloso, Valdilea G.; Pilotto, Jose Henrique; Joao, Esau; Gray, Glenda; Theron, Gerhard; Santos, Breno; Fonseca, Rosana; Kreitchmann, Regis; Pinto, Jorge; Mussi-Pinhata, Marisa M.; Ceriotto, Mariana; Machado, Daisy Maria; Bryson, Yvonne J.; Grinsztejn, Beatriz; Moye, Jack; Klausner, Jeffrey D.; Bristow, Claire C.; Dickover, Ruth; Mirochnick, Mark; Nielsen, Karin (PLOS, 2018-01-05)

Background: Sexually transmitted infections (STIs) including Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Treponema pallidum (TP), and cytomegalovirus (CMV) may lead to adverse pregnancy and infant outcomes. The ...

Point-of-care screening for hepatitis B virus infection in pregnant women at an antenatal clinic : a South African experience

Chotun, Nafiisah; Preiser, Wolfgang; Van Rensburg, Christoffel Johannes; Fernandez, Pedro; Theron, Gerhard Barnard; Glebe, Dieter; Andersson, Monique Ingrid (Public Library of Science, 2017)

Background & aims: Elimination of HIV and syphilis mother-to-child transmission (MTCT) has received much attention but little consideration has been given to the possibility of elimination of HBV MTCT. In sub-Saharan ...

Insertion of intrauterine devices after cesarean section : a systematic review update

Goldstuck, Norman D.; Steyn, Petrus S. (Dove Medical Press, 2017-04-18)

Background: Women who undergo a cesarean section (CS) are in a unique position to receive the intrauterine contraceptive device (IUD). They may also want to use the IUD as a long-acting reversible contraceptive method ...

Standardized outcome measures for pregnancy and childbirth, an ICHOM proposal

Nijagal, Malini A.; Wissig, Stephanie; Stowell, Caleb; Olson, Elizabeth; Amer-Wahlin, Isis; Bonsel, Gouke; Brooks, Allyson; Coleman, Matthew; Karalasingam, Shamala Devi; Duffy, James M. N.; Flanagan, Tracy; Gebhardt, Stefan; Greene, Meridith E.; Groenendaal, Floris; Jeganathan, J. Ravichandran R.; Kowaliw, Tessa; Lamain-de-Ruiter, Marije; Main, Elliott; Owens, Michelle; Petersen, Rod; Reiss, Irwin; Sakala, Carol; Speciale, Anna Maria; Thompson, Rachel; Okunade, Oluwakemi; Franx, Arie (BMC (part of Springer Nature), 2018-12-11)

Background: Value-based health care aims to optimize the balance of patient outcomes and health care costs. To improve value in perinatal care using this strategy, standard outcomes must first be defined. The objective ...

Exploring the feasibility of using mobile phones to improve the management of clients with cervical cancer precursor lesions

Moodley, Jennifer; Constant, Deborah; Botha, Matthys H.; Van der Merwe, Frederick H.; Edwards, Amanda; Momberg, Mariette (BMC (part of Springer Nature), 2019-01-07)

Background: Cancer screening programs hold much potential for reducing the cervical cancer disease burden in developing countries. The aim of this study was to determine the feasibility of mobile health (mHealth) ...

Bereaved mothers' attitudes regarding autopsy of their stillborn baby

Human, M.; Goldstein, R. D.; Groenewald, C. A.; Kinney, H. C.; Odendaal, H. J. (Health and Medical Publishing Group, 2017-12)

Background. Here we present additional information from the Safe Passage Study, where the effect of alcohol exposure during pregnancy on sudden infant death syndrome and stillbirth was investigated. Objective. To explore ...

Vulvar cancer is not a disease of the elderly : treatment and outcome at a tertiary referral centre in South Africa

Butt, J. L.; Botha, M. H. (Health & Medical Publishing Group, 2017)

Background. An increase in vulvar cancer in young women is attributed to infection with oncogenic human papillomavirus (HPV). South Africa (SA) has a high prevalence of HPV, and it was therefore hypothesised that women ...

Tranexamic acid for preventing postpartum haemorrhage

Cluver, Catherine Anne; Novikova, Natalia; Hofmeyr, George Justus (Cochrane, 2015-06-16)

Background: Postpartum haemorrhage (PPH) is a common and potentially life-threatening complication of labour. Several options for preventing PPH are available, but further advances in this field are important, especially ...

Interventions for helping to turn term breech babies to head first presentation when using external cephalic version

Cluver, Catherine Anne; Gyte, Gillian M. L.; Sinclair, Marlene; Dowswell, Therese; Hofmeyr, George Justus (Cochrane, 2015-02-12)

Background: Breech presentation is associated with increased complications. Turning a breech baby to head first presentation using external cephalic version (ECV) attempts to reduce the chances of breech presentation at ...

Women's experiences with cervical cancer screening in a colposcopy referral clinic in Cape Town, South Africa: a qualitative analysis

Momberg, Mariette; Botha, Matthys H.; Van der Merwe, Frederick H.; Moodley, Jennifer (BMJ Publishing Group, 2017-1)

Objective: The aim of this study was to explore and understand women’s experience with cervical cancer screening and with the referral pathways for abnormal Papanicolau (Pap) smears. Design and setting: Focus group ...

Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term

Cluver, Catherine; Novikova, Natalia; Koopmans, Corine M.; West, Helen M. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)

Background: Hypertensive disorders in pregnancy are significant contributors to maternal and perinatal morbidity and mortality. These disorders include well‐controlled chronic hypertension, gestational hypertension ...

Interventions for treating genital Chlamydia trachomatis infection in pregnancy

Cluver, Catherine; Novikova, Natalia; Eriksson, David O. A.; Bengtsson, Kevin; Lingman, Goran K. (John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)

Background: Genital Chlamydia trachomatis (C.trachomatis) infection may lead to pregnancy complications such as miscarriage, preterm labour, low birthweight, preterm rupture of membranes, increased perinatal mortality, ...

Are women with history of pre-eclampsia starting a new pregnancy in good nutritional status in South Africa and Zimbabwe?

Cormick, Gabriela; Betran, Ana Pilar; Harbron, Janetta; Dannemann Purnat, Tina; Parker, Catherine; Hall, David; Seuc, Armando H.; Roberts, James M.; Belizan, Jose M.; Hofmeyr, G. Justus (BioMed Central, 2018-06-15)

Background: Maternal nutritional status before and during pregnancy is an important contributor to pregnancy outcomes and early child health. The aim of this study was to describe the preconceptional nutritional status ...

The CRADLE vital signs alert : qualitative evaluation of a novel device designed for use in pregnancy by healthcare workers in low-resource settings

Nathan, Hannah L.; Boene, Helena; Munguambe, Khatia; Sevene, Esperanca; Akeju, David; Adetoro, Olalekan O.; Charanthimath, Umesh; Bellad, Mrutyunjaya B.; De Greeff, Annemarie; Anthony, John; Hall, David R.; Steyn, Wilhelm; Vidler, Marianne; Von Dadelszen, Peter; Chappell, Lucy C.; Sandall, Jane; Shennan, Andrew H. (BioMed Central, 2018-01-05)

Background: Vital signs measurement can identify pregnant and postpartum women who require urgent treatment or referral. In low-resource settings, healthcare workers have limited access to accurate vital signs measuring ...