Research Articles (Paediatrics and Child Health)
Recent Submissions
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Burkitt lymphoma : trends in children below 15 years reveal priority areas for early diagnosis activities in north-west Cameroon
(AOSIS, 2019)Background: Burkitt lymphoma is one of the most common childhood cancers in Cameroon. Incidence rates of 5.9/100 000 and 2.58 per 100 000 have been reported in two studies in 2005 and 2012 amongst children below 15 years ... -
Working together to build a better future for children with cancer in Africa
(American Society of Clinical Oncology, 2020)ENGLISH ABSTRACT: No abstract available -
Data collection in the Collaborative Wilms Tumour Africa Project
(Elsevier, 2018)ENGLISH ABSTRACT: No abstract available -
The outcome and cost of a capacity-building training programme on the early recognition and referral of childhood cancer for healthcare workers in North-West Cameroon
(John Wiley & Sons Ltd, 2020)Aim: Early cancer diagnosis is necessary to improve survival rates. The aim of this study was to assess the outcome and cost of the childhood cancer training programme amongst healthcare workers. Design: This was a ... -
An ethical imperative : safety and specialization as nursing priorities of WHO Global Initiative for Childhood Cancer
(Wiley Periodicals, Inc., 2019)ENGLISH ABSTRACT: Abstract not available -
Highlights from the 13th African continental meeting of the International Society of Paediatric Oncology (SIOP), 6–9 March 2019, Cairo, Egypt
(ecancermedicalscience, 2019)ENGLISH ABSTRACT: The 13th African continental meeting of the international society of paediatric oncology, held on 6–9 March 2019 in Cairo, was organised in collaboration with the Children Cancer Hospital (57357) in ... -
Management of neuroblastoma in limited-resource settings
(Baishideng Publishing Group Inc., 2020)BACKGROUND: Neuroblastoma (NB) is a heterogeneous disease with variable outcomes among countries. Little is known about NB in low- and middle-income countries (LMICs). AIM: The aim of this review was to evaluate ... -
Validity and feasibility of the self-report EQ-5D-Y as a generic Health-Related Quality of Life outcome measure in children and adolescents with Juvenile Idiopathic Arthritis in Western Cape, South Africa
(AOSIS, 2019)Background: Health-Related Quality of Life (HRQoL) data together with clinical findings allow for monitoring of intervention efficacy and the effect on HRQoL. Children with Juvenile Idiopathic Arthritis (JIA) experience ... -
Disclosure of human immunodeficiency virus status to children in South Africa : a comprehensive analysis
(AOSIS Publishing, 2019)Background: The extent of disclosure of HIV status to children and adolescents and the context facilitating their disclosure process have received little attention. Objectives: To assess disclosure and provide a comprehensive ... -
Direct and indirect effects of the COVID-19 pandemic on children with cardiovascular disease
(South African Heart Association, 2020)ENGLISH ABSTRACT: Coronavirus 2 (SARS-CoV-2) the causative agent of what we now know as “Coronavirus Disease 2019” (COVID-19), is the most serious global health crisis of our generation, with a significant and far-reaching ... -
COVID-19 in pregnancy in South Africa : tracking the epidemic and defining the natural history
(Health & Medical Publishing Group, 2020-08)ENGLISH ABSTRACT: South Africa (SA) has seen a rapid increase in COVID-19 infections in recent weeks, with cases exceeding 40 000 in early June and anticipated to escalate rapidly as lockdown is eased. The country also ... -
Bronchoscopy in children with COVID‐19 : a case series
(John Wiley & Sons, 2020)Introduction: The coronavirus disease‐2019 (COVID‐19) era is a challenging time for respiratory teams to protect their patients and staff. COVID‐19 is predominantly transmitted by respiratory droplets; in the clinical ... -
Bacille Calmette-Guerin (BCG) vaccine and the COVID-19 pandemic : responsible stewardship is needed
(The Union, 2020)We believe that responsible stewardship of the bacille Calmette-Guérin (BCG) vaccine in the context of the COVID-19 epidemic is urgently needed. Live attenuated BCG is currently the only licensed vaccine to protect against ... -
South African healthcare workers and COVID-19 : a shared responsibility to protect a precious and limited resource
(Health & Medical Publishing Group, 2020)Healthcare workers (HCWs) in African countries face high risks of occupational exposure to many pathogens, including tuberculosis, measles, HIV and Ebola.[1,2] The novel coronavirus SARSCoV- 2 poses an arguably greater ... -
Lamivudine monotherapy as a holding regimen for HIV-positive children
(Public Library of Science, 2018-10-11)Background: In resource-limited settings holding regimens, such as lamivudine monotherapy (LM), are used to manage HIV-positive children failing combination antiretroviral therapy (cART) to mitigate the risk of drug ... -
Burkitt lymphoma – nutritional support during induction treatment : effect on anthropometric parameters and morbidity of treatment
(AOSIS, 2018-10-22)Background: Malnutrition is common in children diagnosed with cancer in Africa, and it adds to the morbidity and mortality of treatment. Nutritional support is known to reduce morbidity and mortality of treatment. Aim: ... -
Personal protective equipment (PPE) in a pandemic : approaches to PPE preservation for South African healthcare facilities
(Health & Medical Publishing Group, 2020-04-30)Personal protective equipment (PPE) is key to protecting healthcare workers from COVID-19 infection, but the pandemic has disrupted supply chains globally and necessitated rapid review of the scientific evidence for PPE ... -
Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy
(Wiley Open Access, 2018)Introduction: Early antiretroviral therapy (ART) has improved neurodevelopmental outcomes of HIV-infected (HIV-positive) children; however, little is known about the longer term outcomes in infants commencing early ART ... -
Pediatric Xanthogranulomatus cholangitis
(Elsevier, 2018)ENGLISH ABSTRACT: The Xanthogranulomatous cholangitis is rare entity, usually it happens as an extension of Xanthogranuloma of the gall bladder (XCC) [1], although they are case reports of isolated Xanthogranulomatous ... -
Early childhood caries and dental treatment need in low socio-economic communities in Cape Town, South Africa
(AOSIS, 2018-05-12)Background: Early childhood caries (ECC) is a particularly severe problem in low socio-economic communities which impacts the overall health and well-being of children. The extensive waiting lists for general anaesthesia ...
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