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Central Analytical Facility
Recent Submissions
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Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture
(Nature, 2021)Three-dimensional models are considered a powerful tool for improving the concordance between in vitro and in vivo phenotypes. However, the duration of spheroid culture may influence the degree of correlation between these ... -
Transcriptomic changes associated with husk scald incidence on pomegranate fruit peel during cold storage
(Elsevier, 2020-05-05)Pomegranate fruit is valued for its social, economic, aesthetic and health benefits. The fruit rapidly loses quality after harvest due to continued metabolic responses and physiological disorders under sub-optimal conditions. ... -
Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation
(Nature Research (part of Springer Nature), 2019-02-28)Complex associations exist between inflammation and thrombosis, with the inflammatory state tending to promote coagulation. Fibrinogen, an acute phase protein, has been shown to interact with the amyloidogenic ß-amyloid ... -
Physico-elemental analysis of roasted organic coffee beans from Ethiopia, Colombia, Honduras, and Mexico using X-ray micro-computed tomography and external beam particle induced X-ray emission
(MDPI, 2019)The physico-elemental profiles of commercially attained and roasted organic coffee beans from Ethiopia, Colombia, Honduras, and Mexico were compared using light microscopy, X-ray micro-computed tomography, and external ... -
Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases
(Public Library of Science, 2019-10-24)Background: Approximately 25% of colorectal cancer patients in sub-Saharan Africa are younger than 40 years, and hereditary factors may contribute. We investigated the frequency and patterns of inherited colorectal cancer ... -
Polyphenolic and physicochemical properties of simple-spined num-num (Carissa edulis) fruit harvested at ripe stage of maturation
(MDPI, 2019-07-19)Wildly grown in most regions of the world, Carissa edulis is a highly underutilised fruit with significant antioxidant characteristics. The phyto and physicochemical properties of C. edulis berries at different stages of ... -
A micro X-ray computed tomography dataset of fossil echinoderms in an ancient obrution bed : a robust method for taphonomic and palaeoecologic analyses.
(Oxford University Press, 2019-03)Background: Taphonomic and palaeoecologic studies of obrution beds often employ conventional methods of investigation such as physical removal and extraction of fossils from their host rock (matrix) by mechanical preparation. ... -
Gold exploration in two and three dimensions : improved and correlative insights from microscopy and X-Ray computed tomography
(MDPI, 2020)Abstract: In this contribution, we highlight a correlative approach in which three-dimensional structural/positional data are combined with two dimensional chemical and mineralogical data to understand a complex orogenic ... -
Characterization and cardiovascular effects of (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone, a diterpenoid isolated from Leonotis leonurus
(University of KwaZulu-Natal, 2008)A new diterpenoid, (13S)-9α,13α-epoxylabda-6β(19),15(14)diol dilactone (1), was isolated from Leonotis leonurus and the structure determined via NMR analysis. The compound causes significant changes in blood pressure of ... -
MicroCT imaging applied to description of a new species of Pagurus Fabricius, 1775 (Crustacea: Decapoda: Anomura: Paguridae), with selection of three-dimensional type data
(Public Library of Science, 2018)A new species of hermit crab, Pagurus fraserorum n. sp. (family Paguridae) is described from rocky subtidal reefs off KwaZulu-Natal, South Africa, and illustrated using both conventional drawings and colour photographs, ... -
A micro X-ray computed tomography dataset of South African hermit crabs (Crustacea: Decapoda: Anomura: Paguroidea) containing scans of two rare specimens and three recently described species
(Oxford University Press, 2018-03-14)Background: Along with the conventional deposition of physical types at natural history museums, the deposition of 3-dimensional (3D) image data has been proposed for rare and valuable museum specimens, such as irreplaceable ...