Research Articles (Centre for Evidence-Based Health Care)
Recent Submissions
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Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults
(John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2019)Background: Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the newest version, are the only World Health Organization (WHO)- recommended rapid tests that simultaneously detect tuberculosis and ... -
University curricula in evidence-informed decision making and knowledge translation : integrating best practice, innovation, and experience for effective teaching and learning
(Frontiers Media, 2019)As attention to Evidence Informed Decision Making (EIDM) and Knowledge Translation (KT) in research, policy and practice grows, so does a need for capacity enhancement in amongst evidence producers and evidence users. ... -
Advancing research integrity : a programme to embed good practice in Africa
(Pan African Medical Journal, 2019-08-13)In Africa, training programmes as well as institutional policies on research integrity are lacking. Institutions have a responsibility to oversee research integrity through various efforts, including policies and training. ... -
Burden of non-communicable diseases in sub-Saharan Africa, 1990–2017 : results from the Global Burden of Disease Study 2017
(Elsevier, 2019-10)Background: Although the burden of disease in sub-Saharan Africa continues to be dominated by infectious diseases, countries in this region are undergoing a demographic transition leading to increasing prevalence of ... -
Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study : a 7-day prospective observational cohort study
(Elsevier, 2019-04)Background: Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor maternal and neonatal outcomes. Methods: A 7-day, ... -
Mapping evidence on standards and quality of care for older persons in long-term care facilities : a scoping review protocol
(BMC (part of Springer Nature), 2021-05-22)Background: Ageing is a global and universal process that results in physiological, psychological and behavioural changes. Due to the changing needs of the individual and the circumstances of the family, long-term care of ... -
Priority setting for new systematic reviews : processes and lessons learned in three regions in Africa
(BMJ Publishing Group, 2019)Priority setting to identify topical and context relevant questions for systematic reviews involves an explicit, iterative and inclusive process. In resource-constrained settings of low-income and middle-income countries, ... -
Individual and contextual correlates of mosquito net use among women in Nigeria
(BMC (part of Springer Nature), 2020-04-07)Background: Malaria has been described as an urgent public health priority with almost half of the world’s population being at risk. Use of insecticide-treated nets is considered one of the effective ways of preventing ... -
Transmission of respiratory viruses when using public ground transport : a rapid review to inform public health recommendations during the COVID-19 pandemic
(Health & Medical Publishing Group, 2020-05-07)In response to the COVID-19 pandemic, numerous countries worldwide declared national states of emergency and implemented interventions to minimise the risk of transmission among the public. Evidence was needed to inform ... -
Exploring the evolution of engagement between academic public health researchers and decision-makers : from initiation to dissolution
(BMC (part of Springer Nature), 2020-02-10)Context: Relationships between researchers and decision-makers have demonstrated positive potential to influence research, policy and practice. Over time, interest in better understanding the relationships between the two ... -
Assessing the completeness and comparability of outcomes in systematic reviews addressing food security : protocol for a methodological study
(BMC (part of Springer Nature), 2020-01-09)Background: Systematic reviews should specify all outcomes at the protocol stage. Pre-specification helps prevent outcome choice from being influenced by knowledge of included study results. Completely specified ... -
Understanding the implications of the Sustainable Development Goals for health policy and systems research : results of a research priority setting exercise
(BMC (part of Springer Nature), 2020-01-09)Background: Given the paradigmatic shift represented by the Sustainable Development Goals (SDGs) as compared to the Millennium Development Goals - in particular their broad and interconnected nature - a new set of ... -
Hepatitis C prevalence in HIV-infected heterosexual men and men who have sex with men
(Health & Medical Publishing Group, 2018)Background. Globally 1% of individuals are infected with hepatitis C virus (HCV). In South Africa (SA) the prevalence ranges between 0.3% and 1%, with few prospective screening data available. Similarly, local data on ... -
Nutritional supplements for people being treated for active tuberculosis : a technical summary
(Health & Medical Publishing Group, 2018)Tuberculosis and nutrition are intrinsically linked in a complex relationship. Altered metabolism and loss of appetite associated with tuberculosis may result in undernutrition, which in turn may worsen the disease or delay ... -
A systematic review of strategies for reducing missed opportunities for vaccination
(Elsevier, 2018)Background: Missed opportunities for vaccination (MOVs) occur when persons eligible for vaccination visit a health facility and do not get the vaccines they need. We conducted a systematic review to assess effects of ... -
Psychological interventions for alcohol use disorders in people living with HIV/AIDS : a systematic review
(BMC (part of Springer Nature), 2019-10-28)Background: Alcohol use disorders (AUDs) in people living with HIV/AIDS (PLWH) are a significant impediment to achieving virological control. HIV non-suppression in PLWH with AUDs is mainly attributable to sub-optimal ... -
Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease : protocol for a systematic review
(BMJ Publishing Group, 2018-02)Introduction Rheumatic heart disease (RHD) is a preventable and treatable chronic condition which persists in many developing countries largely affecting impoverished populations. Handheld echocardiography presents an ... -
Plagiarism in research : a survey of African medical journals
(BMJ Publishing Group, 2018-11)Objectives To examine whether regional biomedical journals in Africa had policies on plagiarism and procedures to detect it; and to measure the extent of plagiarism in their original research articles and reviews. Design ... -
Investigation of household contacts of pulmonary tuberculosis patients increases case detection in Mwanza City, Tanzania
(BioMed Central, 2018-03)Background: Tuberculosis (TB) contact tracing is a key strategy for containing TB and provides addition to the passive case finding approach. However, this practice has not been implemented in Tanzania, where there is ... -
Next generation clinical guidance for primary care in South Africa – credible, consistent and pragmatic
(Public Library of Science, 2018-03-30)Background: Agreed international development standards underpin high quality de novo clinical practice guidelines (CPGs). There is however, no international consensus on how high quality CPGs should ‘look’; or on whether ...
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