Research Articles (Centre for Evidence-Based Health Care)
Recent Submissions
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Next generation clinical guidance for primary care in South Africa – credible, consistent and pragmatic
(Public Library of Science, 2018-03-30)Background: Agreed international development standards underpin high quality de novo clinical practice guidelines (CPGs). There is however, no international consensus on how high quality CPGs should ‘look’; or on whether ... -
Global emergency care clinical practice guidelines : a landscape analysis
(Elsevier, 2018)Introduction: An adaptive guideline development method, as opposed to a de novo guideline development, is dependent on access to existing high-quality up-to-date clinical practice guidelines (CPGs). We described ... -
An analysis of trunk kinematics and gait parameters in people with stroke
(AOSIS, 2018)Background: Approximately two out of three people with stroke experience gait problems. Trunk movement control and symmetry is an important prerequisite for functional walking gait. Movement control, measured objectively ... -
Prehospital providers’ perspectives for clinical practice guideline implementation and dissemination : strengthening guideline uptake in South Africa
(Public Library of Science, 2019)Background: In 2016 the first African emergency care clinical practice guideline (CPG) was developed for national uptake in the prehospital sector in South Africa, with implementation starting in 2018. Comprehensive uptake ... -
Prevention and treatment of acute malnutrition in humanitarian emergencies : a multi-organisation collaboration to increase access to synthesised evidence
(SpringerOpen (part of Springer Nature), 2019-05-31)Background: Program decision-making to prevent and treat acute malnutrition in an emergency can be hampered by a lack of accessible and relevant overviews of directly available robust research evidence. There is often ... -
Critical care admission of South African (SA) surgical patients : results of the SA surgical outcomes study
(Health and Medical Publishing Group, 2017)Background. Appropriate critical care admissions are an important component of surgical care. However, there are few data describing postoperative critical care admission in resource-limited low- and middle-income ... -
Quality of abstracts of pilot trials in heart failure : a protocol for a systematic survey
(Elsevier, 2017)Introduction: Pilot trials are initial small-scale studies done to inform the design of larger trials. Their findings like other studies are usually disseminated as peer-reviewed journal articles. Abstracts are used to ... -
Nutritional status of children on the National School Nutrition Programme in Capricorn District, Limpopo Province, South Africa
(Health and Medical Publishing Group, 2017)Background. School feeding programmes are intended to alleviate short-term hunger, improve nutrition and cognition of children, andprovide incomes to families.Objectives. To assess the nutritional status of children receiving ... -
Integrated models of care for diabetes and hypertension in low- and middle-income countries (LMICs) : protocol for a systematic review
(BMC (part of Springer Nature), 2018)Background: In low- and middle-income countries (LMICs), the burden of non-communicable diseases (NCDs) is growing against an existing burden of other diseases such as HIV/AIDS. Integrated models of care can help address the ... -
Calcium channel blockers for people with chronic kidney disease requiring dialysis
(Cochrane, 2014)This is the protocol for a review and there is no abstract. The objectives are as follows: This review aims to look at the benefits and harms of CCB for people with CKD requiring dialysis. -
Task shifting from doctors to non-doctors for initiation and maintenance of antiretroviral therapy
(Cochrane, 2014)Background: The high levels of healthcare worker shortage is recognised as a severe impediment to increasing patients’ access to antiretroviral therapy. This is particularly of concern where the burden of disease is ... -
Transcutaneous screening for hyperbilirubinemia in neonates
(Cochrane, 2014)This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate to the effects of transcutaneous screening for hyperbilirubinemia to prevent the readmission of neonates for phototherapy. -
Nutritional supplements for people being treated for active tuberculosis
(Cochrane, 2016-06-29)Background: Tuberculosis and malnutrition are linked in a complex relationship. Tuberculosis may cause undernutrition through increasedmetabolic demands and decreased intake, and nutritional deficiencies may worsen the ... -
Public stewardship of private for-profit healthcare providers in low- and middle-income countries
(Cochrane, 2016-08-11)Background: Governments use different approaches to ensure that private for-profit healthcare services meet certain quality standards. Such government guidance, referred to as public stewardship, encompasses government ... -
Brief school-based interventions and behavioural outcomes for substance-using adolescents
(Cochrane, 2016-01-20)Background: Adolescent substance use is a major problem in and of itself, and because it acts as a risk factor for other problem behaviours. As substance use during adolescence can lead to adverse and often long-term ... -
Interventions for improving coverage of childhood immunisation in low- and middle-income countries
(Cochrane, 2016-07-10)Background: Immunisation is a powerful public health strategy for improving child survival, not only by directly combating key diseases that kill children but also by providing a platform for other health services. However, ... -
Barriers and enablers for the development and implementation of allied health clinical practice guidelines in South African primary healthcare settings : a qualitative study
(BioMed Central, 2017)Background: The South African allied health (AH) primary healthcare (PHC) workforce is challenged with the complex rehabilitation needs of escalating patient numbers. The application of evidence-based care using clinical ... -
Vector and reservoir control for preventing leishmaniasis
(Cochrane, 2015-08-05)Background: Leishmaniasis is caused by the Leishmania parasite, and transmitted by infected phlebotomine sandflies. Of the two distinct clinical syndromes, cutaneous leishmaniasis (CL) affects the skin and mucous membranes, ... -
Treatments for breast abscesses in breastfeeding women
(Cochrane, 2015-08-17)Background: The benefits of breastfeeding are well known, and the World Health Organization recommends exclusive breastfeeding for the first six months of life and continuing breastfeeding to age two. However, many women ... -
Interventions for preventing postpartum constipation
(Cochrane, 2015-09-18)Background: Postpartum constipation, with symptoms such as pain or discomfort, straining, and hard stool, is a common condition affecting mothers. Haemorrhoids, pain at the episiotomy site, effects of pregnancy hormones ...
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