(PLoS, 2015-03) Weighill, Deborah A.; Jacobson, Daniel A.
We present and develop the theory of 3-way networks, a type of hypergraph in which each
edge models relationships between triplets of objects as opposed to pairs of objects as
done by standard network models. We explore approaches of how to prune these 3-way
networks, illustrate their utility in comparative genomics and demonstrate how they find relationships
which would be missed by standard 2-way network models using a phylogenomic
dataset of 211 bacterial genomes.