Browsing by Author "Bezuidenhout, D. J. J."
Now showing 1 - 8 of 8
Results Per Page
Sort Options
- ItemThe association between ulcerative colitis and chronic liver disease at Tygerberg Hospital(Health and Medical Publishing Group -- HMPG, 1982-02) Perold, J. G.; Bezuidenhout, D. J. J.; Erasmus, T. D.; Middlecote, B. D.Twenty consecutive patients with ulcerative colitis were evaluated at the Gastro-intestinal Clinic, Tygerberg Hospital, with special reference to the biochemical tests and histological findings in the liver. Abnormal liver function tests warrant a liver biopsy, since the underlying liver disease influences the subsequent prognosis and treatment.
- ItemA comparison of 4-week peptic ulcer healing rates following treatment with antacids and ranitidine(Health and Medical Publishing Group (HMPG), 1984-06) Bezuidenhout, D. J. J.; Perold, J. G.; Adams, G.Eighty-eight patients with endoscopically proven gastric and duodenal ulceration were treated with ranitidine (Zantac; Glaxo) or an antacid preparation containing aluminium hydroxide and magnesium trisilicate (Gelusil; Warner) over a 4-week period to assess healing. Clinical, haematological and biochemical assessment and endoscopy were performed at the beginning and at the end of this period. Of the duodenal ulcers, 74% healed on ranitidine therapy and 63% on Gelusil. This difference was not statistically significant (χ2(1) = 0,55). Of the gastric ulcers 58% healed on ranitidine therapy and 35% on Gelusil, but this difference did not reach statistical significance (χ2(1) = 1,79). There was no significant difference between the two therapies with regard to symptomatic relief in the duodenal ulcer group, but ranitidine produced significantly better results in the gastric ulcer group. No side-effects were noted in either group.
- ItemDubbele pilorus en piloroduodenale fistels : twee gevalbeskrywings met bespreking(Health & Medical Publishing Group, 1984) Keet, A. D.; Bezuidenhout, D. J. J.Congenital double pylorus is extremely rare; only 2 cases have been found in the English and French literature. Acquired double pylorus occurs more often; up to 1982, 66 cases had been reported. During 6,810 consecutive barium meal examinations over a period of 2 years, we diagnosed the condition in 5 patients. Two came to operation, at which the diagnosis was confirmed. These 2 cases are described. Acquired double pylorus is in reality a short pyloroduodenal fistula situated next to the pylorus, usually on the lesser curvature side. In the majority of cases it results from a pyloric ulcer penetrating into the duodenum. In a minority of cases the primary lesion is a duodenal ulcer penetrating into the pyloric area. Cases initially present with peptic ulcer symptoms. With the formation of the fistula, symptoms may disappear. Some authorities consider this to indicate spontaneous cure of the ulcer, thus obviating the need for further medical or surgical treatment. In the present 2 cases there was no remission of symptoms. None of the cases has been associated with malignant disease. It is thought that the condition may be recognized more often in future.
- ItemFolate levels in patients with ulcerative colitis receiving sulphasalazine(Health & Medical Publishing Group, 1984) Schoeman, M.; Bezuidenhout, D. J. J.The question of folate deficiency in patients receiving sulphasalazine is still controversial. A random sample of patients with ulcerative colitis receiving sulphasalazine were studied to determine the clinical significance of the inhibition of folic acid absorption by the drug. No significant lowering of folate levels could be determined.
- ItemGastric carcinoma at Tygerberg Hospital, 1979 - 1983 : a retrospective study(Health and Medical Publishing Group (HMPG), 1985-12) Van Eeden, P. J.; Bezuidenhout, D. J. J.A retrospective study was carried out on patients with histologically proven gastric carcinoma diagnosed at the Gastro-intestinal Clinic, Tygerberg Hospital, over a 5-year period - 1979 - 1983. Fifty per cent of patients were coloured men. The overall median age was 65 years but the coloured patients were significantly younger than the white. The main symptoms were loss of appetite and weight, abdominal pain and vomiting. The duration of symptoms in all patients was 3 months. An abdominal mass, anaemia and obvious weight loss were the most important physical signs. A normocytic, normochromic anaemia, an elevated erythrocyte sedimentation rate, raised liver enzyme levels and hypo-albuminaemia were the most important laboratory findings. In 96% of the 149 patients gastroscopy yielded a positive diagnosis of gastric carcinoma and barium meal examination showed abnormalities in 87%. In the majority of cases the carcinoma was poorly differentiated.
- ItemGastric juice carcino-embryonic antigen estimation : a useful additional test in the diagnosis of gastric carcinoma?(Health & Medical Publishing Group, 1987) Van Eeden, P. J.; Bezuidenhout, D. J. J.; Kock, J.There is a high incidence of gastric carcinoma in the coloured population of the Western Cape. Diagnostic tests other than barium meal examination or gastroscopy were investigated. In this study 50 patients were assessed and grouped according to the gastroscopic and histological findings. Twenty-five patients with gastric carcinoma and 25 with benign gastric ulcer and/or chronic atrophic gastritis and/or intestinal metaplasia were tabulated. The gastric juice and plasma carcino-embryonic antigen (CEA) levels were evaluated and compared in the two groups. The gastric juice CEA level was more useful than the plasma CEA level as an aid in diagnosing malignant gastric lesions. No correlation was evident between CEA values and the extent of the gastric carcinoma and or histological typing. An elevated gastric juice CEA level was an additional aid in diagnosing gastric carcinoma. Markedly elevated values may also identify the high-risk patient who is prone to develop gastric carcinoma.
- ItemHydatid cysts simulating massive ascites : a case report(Health & Medical Publishing Group, 1986) Adams, G.; Bezuidenhout, D. J. J.A patient with the clinical features of massive ascites was found to have extensive intra-abdominal hydatid cysts.
- ItemJuveniele pernisieuse anemie in 'n 28-jarige Kleurlingvrou : 'n gevalbespreking(Health & Medical Publishing Group, 1982) Wagener, G. W. W.; Bezuidenhout, D. J. J.A case of classic addisonian pernicious anaemia is described in a 28-year-old Coloured woman with a 15-year history of anaemia.