Nephrology

Recent Submissions

  • Peritoneal dialysis technique survival at Tygerberg hospital in Cape Town, South Africa 

    Kapembwa, Kenneth Chali (Stellenbosch : Stellenbosch University, 2017-03)
    Background: Peritoneal dialysis (PD) technique failure invariably occurs in patients with end-stage renal disease who are treated with this modality and results in increased morbidity and mortality. Various factors have ...

  • A renal registry for Africa : first steps 

    Davids, M. Razeen; Eastwood, John B.; Selwood, Neville H.; Arogundade, Fatiu A.; Ashuntantang, Gloria; Gharbi, Mohammed Benghanem; Jarraya, Faical; MacPhee, Iain A. M.; McCulloch, Mignon; Plange-Rhule, Jacob; Swanepoel, Charles R.; Adu, Dwomoa (Oxford University Press European Renal Association, 2016)
    ENGLISH ABSTRACT: There is a dearth of data on end-stage renal disease (ESRD) in Africa. Several national renal registries have been established but have not been sustainable because of resource limitations. The African ...

  • Quality of life in patients on chronic dialysis in South Africa : a comparative mixed methods study 

    Tannor, Elliot K.; Archer, Elize; Kapembwa, Kenneth; Van Schalkwyk, Susan C.; Davids, M. Razeen (BioMed Central, 2017-01-05)
    Background: The increasing prevalence of treated end-stage renal disease and low transplant rates in Africa leads to longer durations on dialysis. Dialysis should not only be aimed at prolonging lives but also improve ...

  • Validation of two prediction models of undiagnosed chronic kidney disease in mixed-ancestry South Africans 

    Mogueo, Amelie; Echouffo-Tcheugui, Justin B.; Matsha, Tandi E.; Erasmus, Rajiv T.; Kengne, Andre P. (BioMed Central, 2015-07-04)
    Background: Chronic kidney disease (CKD) is a global challenge. Risk models to predict prevalent undiagnosed CKD have been published. However, none was developed or validated in an African population. We validated the Korean ...

  • Use of the accountability for reasonableness approach to improve fairness in accessing dialysis in a middle- income country 

    Moosa, Mohammed Rafique; Maree, Jonathan David; Chirehwa, Maxwell T.; Benatar, Solomon R. (Public Library of Science, 2016)
    Universal access to renal replacement therapy is beyond the economic capability of most low and middle-income countries due to large patient numbers and the high recurrent cost of treating end stage kidney disease. In ...

  • Important causes of chronic kidney disease in South Africa 

    Moosa, M. R.; Van Der Walt, I.; Naicker, S.; Meyers, A. M. (Health & Medical Publishing Group, 2015)
    In hypertensive patients without chronic kidney disease (CKD) the goal is to keep blood pressure (BP) at ≤140/90 mmHg. When CKD is present, especially where there is proteinuria of ≥0.5 g/day, the goal is a BP of ≤130/80 ...

  • Bolus administration of intravenous glucose in the treatment of hyperkalemia : a randomized controlled trial 

    Chothia, Mogamat-Yazied; Halperin, Mitchell L.; Rensburg, Megan A.; Hassan, Mogamat Shafick; Davids, Mogamat Razeen (Karger, 2014-02)
    Background: Hyperkalemia is a common medical emergency that may result in serious cardiac arrhythmias. Standard therapy with insulin plus glucose reliably lowers the serum potassium concentration ([K + ]) but carries ...

  • Effect of improving the usability of an e-learning resource : a randomized trial 

    Davids, Mogamat Razeen; Chikte, Usuf M. E.; Halperin, Mitchell L. (HighWire, 2014-06)
    Optimizing the usability of e-learning materials is necessary to reduce extraneous cognitive load and maximize their potential educational impact. However, this is often neglected, especially when time and other resources ...

  • Usability testing of a multimedia e-learning resource for electrolyte and acid-base disorders 

    Davids, MR; Chikte, Usuf; Grimmer-Somers, Karen; Halperin, Mitchell L. (Wiley Online Open, 2013-04)
    The usability of computer interfaces may have a major influence on learning. Design approaches that optimize usability are commonplace in the software development industry but are seldom used in the development of e-learning ...

  • Development and evaluation of a multimedia e-learning resource for electrolyte and acid-base disorders 

    Davids, MR; Chikte, Usuf M. E.; Halperin, Mitchell L. (American Physiological Society, 2011-10)
    This article reports on the development and evaluation of a Web-based application that provides instruction and hands-on practice in managing electrolyte and acid-base disorders. Our teaching approach, which focuses on ...

  • The role of the endothelium in the reduction of restenosis following balloon angioplasty 

    Davids, MR; Page, C.; Muller, C. J.; Rossouw, D. J.; Doubell, A. F. (Clinics Cardive Publishing, 1998-10)
    Objective. Coronary angioplasty is complicated in one-third of cases by restenosis due to intimal hyperplasia. This is the result of the migration and proliferation of vascular smooth-muscle cells (SMCs) and correlates ...

  • Misuse of blood 

    Burman, N. D. (HMPG, 1977-11)
    LETTER: In recent months an increasing number of patients have been referred to us by doctors from outside with a standard note: "... breathlessness ... tiredness ... anaemia (4-8 g/100 ml) ... blood transfusion given ... ...

  • An audit of 24-hour creatinine clearance measurements at Tygerberg Hospital and comparison with prediction equations 

    Le Riche, Mia; Zemlin, Annalise E.; Erasmus, Rajiv T.; Davids, MR (Health and Medical Publishing Group (HMPG), 2007-10)
    BACKGROUND: Internationally, clinical guidelines recommend the use of creatinine-based equations to estimate glomerular filtration rate (GFR) for assessment and follow-up of kidney disease. The routine use of 24-hour ...