SUNScholar is a leading digital archive for the preservation and promotion of the research output of Stellenbosch University.
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Recently Added
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Incident tuberculosis disease in patients receiving biologic therapies in the Western Cape, South Africa from 2007 to 2018
(BMC (part of Springer Nature), 2019)Background: South Africa has one of the highest tuberculosis incidence rates. Biologic disease-modifying antirheumatic drugs are associated with an increased risk of tuberculosis. The objective of this study was to ... -
Photo-essays : a creative format for effective communication
(African Sun Media, 2020)Scientists and educators regularly face the challenge of effectively, concisely and interestingly communicating their ideas and findings, and the need to engage readers unfamiliar with the concepts or issues they want ... -
Anaesthetic induction with propofol: How much? How fast? How slow? What determines anesthetic induction dose? It’s the Front-End Kinetics, Doctor!
(Medpharm Publications, 2019)It has long been realised that linear dosing according to total body weight (TBW) results in overdosing obese patients and under-dosing small children. Injected drug doses calculated on a mg.kg-1 body weight basis work ... -
Anaesthetic management of a three-month-old baby for cervical limited dorsal myeloschisis repair using propofol and alfentanil infusions guided by pharmacokinetic simulation software :aA case report
(Medpharm Publications, 2019)We present an uncommon case of limited dorsal myeloschisis in a 3-month-old infant requiring repair guided by intraoperative neuromonitoring (IONM) and therefore avoidance of volatile anaesthetic agents. The case presented ... -
Skin disinfection practice before skin anaesthesia, prior to neuraxial blockade : a survey of government hospital practices in South Africa
(Medpharm Publications, 2019)Infectious complications following neuraxial block, although being of low incidence, may lead to morbidity and mortality. Two common methods utilised for skin disinfection before skin anaesthesia prior to a neuraxial block ... -
Induction of anaesthesia with propofol according to the adjusted ideal body mass in obese and nonobese patients : an observational study
(Taylor & Francis Group, 2019)Obesity changes body composition including fat free mass (FFM), regarded as the “pharmacologically active mass”. Scaling drug doses to obese patients by total body mass (TBM) results in overdose. We aimed to determine the ... -
Diabetes in pregnancy : lessons for developing countries
(African Sun Media, 2020)Pregnancy diabetes is fast becoming a common condition across the world with developing countries particularly affected. In the short term, maternal hyperglycaemia worsens pregnancy outcomes, but in the long run, it ... -
Hyperglycaemia in pregnancy
(African Sun Media, 2020)According to the International Diabetes Federation, the burden of diabetes is progressively rising worldwide with an expected doubling of prevalence in most low- and middle-income settings within twenty-five years. The ... -
Age or maturity? African children’s right to participate in medical decision-making processes
(Pretoria University Law Press, 2020)This article advocates an approach to children’s participation in medical decision-making processes guided by the rationality of the best interests’ principle, a child’s evolving capacity and a child’s age. Using a human ... -
Calibrating children’s rights to participate in a family setting 30 years after the adoption of the convention on the rights of the child and the African Children’s Charter
(University of Fort Hare, 2021)Efforts to ensure compliance with Article 12 of the United Nations Convention on the Rights of the Child (CRC) and Articles 4(2) and 7 of the African Charter on the Rights and Welfare of the Child (Children’s Charter), ... -
How environmental exposures early in life might influence phenotypes of non-cummunicable diseases in Africa
(African Sun Media, 2020)Chronic non-communicable diseases, such as diabetes, cancer, cardiovascular and chronic respiratory diseases are leading causes of death and disability in the world – accounting for over 60 per cent of the nearly 60 ... -
The challenges of breastfeeeding in poor urban areas in sub-Saharan Africa
(African Sun Media, 2020)Optimal breastfeeding has the potential to prevent more than 800 000 deaths in children younger than five years; 500 000 neonatal deaths; and 20 000 deaths in women every year. Despite these benefits, evidence from ... -
The fundamental importance of breastfeeding for health and development
(African Sun Media, 2020)How an infant is nourished in early life is central to the DOHaD hypothesis regarding the later onset of chronic non-communicable diseases, especially where feeding practices result in either stunting of growth or excessive ... -
Relation between famine and health in future generations : potential knowledge translation to Africa
(African Sun Media, 2020)Nutrition provides the essential building blocks for human health. Although there is enough food on the planet to feed all its inhabitants, inequality in access to food poses serious threats to humanity. Poor nutrition, ... -
Mapping of developmental origins of health and disease to 'Sustainable Development Goals' and implications for public health in Africa
(African Sun Media, 2020)A call for new approaches and knowledge systems has emerged, to map the way forward for the ‘Sustainable Development Goals’ in Africa.6 Public health on the continent, calls for an approach to effect changes to reach the ... -
The implications of developmentel origins of health and disease for Africa : what can be learnt from available data?
(African Sun Media, 2020)There is a broad spectrum of knowledge globally that shows that specific exposures in early life – during pregnancy and early childhood – might affect what happens at various later stages of life. The scientific field ... -
Ensuring healthier trajectories that start in early life to assist non-communicable disease prevention in Africa : a life-course approach
(African Sun Media, 2020)Non-communicable diseases are increasing globally, particularly in low- and middle-income countries. For countries on the African continent, this is of particular concern as the combination of a persisting burden of ... -
International Society for Developmental Origins of Health and Disease's work at the Stellenbosch Institute for Advanced Study
(African Sun Media, 2020)This chapter describes the core group at the Stellenbosch Institute for Advanced Study (STIAS) who have contributed to the long-term theme project, ‘Health in Transition’. It also describes what this book is about, why ... -
Characterization of coloured gemstones by X-ray micro computed tomography
(MDPI, 2021)The monetary value of gemstones is based on five variables: rarity, cut, weight, color and clarity. The latter refers to internal impurities and defects. Fashion may also dictate demand and price. To enhance some of these ... -
Preparing graduates for interprofessional practice in South Africa : the dissonance between learning and practice
(Frontiers Media, 2021)With South Africa's tumultuous history and resulting burden of disease and disability persisting post-democracy in 1994, a proposed decentralization of heath care with an urgent focus on disease prevention strategies ensued ... -
Obesity and other nutrition related abnormalities in pre-dialysis chronic kidney disease (CKD) participants
(MDPI, 2020)Chronic kidney disease (CKD) is increasing in sub-Saharan Africa. Undernutrition has been prevalent amongst end stage CKD patients, with limited data on the prevalence of obesity. The aim of this study was to assess the ... -
Variability of sea-air carbon dioxide flux in autumn across the Weddell gyre and offshore dronning maud land in the southern ocean
(Frontiers Media, 2019)Sea surface fugacity of carbon dioxide (fCO2ssw) was measured across the Weddell gyre and the eastern sector in the Atlantic Southern Ocean in autumn. During the occupation between February and April 2019, the region of ... -
Creating and maintaining a commercially viable executive coaching practice in South Africa
(AOSIS Publishing, 2019)Background: The executive coaching industry is growing internationally and in South Africa. As is typical of small businesses, many struggle to survive. Factors contributing to small business success have been researched, ... -
Managing gestational trophoblastic neoplasm (GTN) and people living with HIV (PLWH)
(MedPharm Publications, 2019)The 2017 World Health Organization (WHO) global report on HIV/AIDS estimated that sub-Saharan Africa comprised 64% of the global HIV burden, with a current estimate of 19.4 million cases in Eastern and Southern Africa. ... -
Factors influencing the confidence and knowledge of nurses prescribing antiretroviral treatment in a rural and urban district in the Western Cape province
(AOSIS Publishing, 2019)Background: Since the introduction of nurse-initiated and managed antiretroviral treatment (NIMART) in South Africa in 2010, initiation of antiretroviral therapy (ART) in primary care has become the responsibility of nurses. ... -
Rapid emergence of resistance to antiretroviral treatment after undisclosed prior exposure : a case report
(AOSIS Publishing, 2019)Introduction: Patients who disengaged from care may present as therapy naïve for antiretroviral treatment (ART) initiation at a different site, without being recognised as being at an increased risk of rapid treatment ... -
Disclosure of human immunodeficiency virus status to children in South Africa : a comprehensive analysis
(AOSIS Publishing, 2019)Background: The extent of disclosure of HIV status to children and adolescents and the context facilitating their disclosure process have received little attention. Objectives: To assess disclosure and provide a comprehensive ... -
The impact of COVID-19 on chess in South Africa
(CSSALL Publishers, 2020)In this chapter I address the question of the way that the outbreak of the COVID-19 pandemic with its new normal and social distancing, impacts the sport code of chess in South Africa. This pandemic has already drastically ... -
Unfinished business? Faith communities and reconciliation in a post-TRC context
(African Sun Media, 2020)This publication takes one back to the Truth and Reconciliation Commission’s (TRC) Faith Communities’ Hearings in 1997 and the re-enactment of those hearings in 2014. Some communities revisit their support of those in power ... -
Teacher education for transformative agency : critical perspectives on design, content and pedagogy
(African Sun Media, 2020)"Many teacher education programs globally are undergoing significant changes in response to government policy, imperatives driven by global competitiveness, as well as local conditions. This is particularly relevant in the ...