Validity and feasibility of the self-report EQ-5D-Y as a generic Health-Related Quality of Life outcome measure in children and adolescents with Juvenile Idiopathic Arthritis in Western Cape, South Africa
Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
AOSIS
Abstract
Background: Health-Related Quality of Life (HRQoL) data together with clinical findings
allow for monitoring of intervention efficacy and the effect on HRQoL. Children with Juvenile
Idiopathic Arthritis (JIA) experience symptoms often persisting into adulthood, emphasising
the need to track HRQoL.
Objectives: The aim of this study was to investigate psychometric properties of the EuroQol
five-dimensional youth questionnaire (EQ-5D-Y) in children with JIA.
Methods: A cross-sectional, analytical study design was used. Children 8 to 15 years were
recruited, completing the self-report EQ-5D-Y and two other HRQoL questionnaires. Known
group validity was established by comparing the effect size between children with different
disease severities. Concurrent validity was tested using Kruskal–Wallis to compare the ranking
of scores on different questionnaires. Feasibility was assessed by number of missing responses
and time to complete each questionnaire.
Results: All questionnaires were able to distinguish between children with different
JIA severity. There was a significant difference in ranking of most Juvenile Arthritis
Multidimensional Assessment Report dimension scores across EQ-5D-Y levels, (p < 0.05),
indicating concurrent validity. There was poor concurrent validity with the PedsQL dimensions
tested with EQ-5D-Y, except for ‘pain’ (p = 0.001). The EQ-5D-Y was the quickest to complete
with no missing values.
Conclusion: This study showed that the EQ-5D-Y is valid and feasible in measuring HRQoL
in JIA children and adequately responsive to detect change over time.
Clinical implications: It is quick and easy to use in a busy clinical setting, allowing for effective
JIA management monitoring.
Description
CITATION: Scott, D., et al. 2019. Validity and feasibility of the self-report EQ-5D-Y as a generic Health-Related Quality of Life outcome measure in children and adolescents with Juvenile Idiopathic Arthritis in Western Cape, South Africa. South African Journal of Physiotherapy, 75(1):a1335, doi:10.4102/sajp.v75i1.1335.
The original publication is available at http://www.sajp.co.za
The original publication is available at http://www.sajp.co.za
Keywords
Autoimmune diseases -- Children, Juvenile Idiopathic Arthritis, Quality of life -- Health aspects
Citation
Scott, D., et al. 2019. Validity and feasibility of the self-report EQ-5D-Y as a generic Health-Related Quality of Life outcome measure in children and adolescents with Juvenile Idiopathic Arthritis in Western Cape, South Africa. South African Journal of Physiotherapy, 75(1):a1335, doi:10.4102/sajp.v75i1.1335