Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample
dc.contributor.author | Van Rensburg E.J. | |
dc.contributor.author | Engelbrecht S. | |
dc.contributor.author | Van Heerden W.F.P. | |
dc.contributor.author | Raubennheimer E.J. | |
dc.contributor.author | Schoub B.D. | |
dc.date.accessioned | 2011-05-15T16:15:33Z | |
dc.date.available | 2011-05-15T16:15:33Z | |
dc.date.issued | 1996 | |
dc.description.abstract | Background. The incidence of oral squamous cell carcinoma (OSCC) is on the increase in developing countries. Materials and Methods. Formalin fixed paraffin embedded blocks of OSCCs from a Black South African population sample of peri-urban and rural origin were selected as follows: Group 1-57 OSCCs with a mean age of 59 years; Group 2 - 43 OSCCs all cases younger than 40 years; Group 3 - 46 OSCCs with blocks containing only tumour tissue without any normal epithelium and Group 4, a control group of 38 non-neoplastic epithelial lesions. Type specific primers were used in a standard PCR to amplify a segment of the E6 region of HPV 6, 11, 16 and 18. Results. HPV 11 and 16 DNA were found in one sample each from groups 1 and 2 respectively. Conclusion. HPV is not an etiologic factor in the development of OSCC in the population studied. | |
dc.description.version | Article | |
dc.identifier.citation | Anticancer Research | |
dc.identifier.citation | 16 | |
dc.identifier.citation | 2 | |
dc.identifier.issn | 02507005 | |
dc.identifier.uri | http://hdl.handle.net/10019.1/13387 | |
dc.subject | formaldehyde | |
dc.subject | paraffin | |
dc.subject | virus dna | |
dc.subject | adult | |
dc.subject | aged | |
dc.subject | article | |
dc.subject | controlled study | |
dc.subject | developing country | |
dc.subject | female | |
dc.subject | human | |
dc.subject | human tissue | |
dc.subject | male | |
dc.subject | mouth carcinoma | |
dc.subject | negro | |
dc.subject | polymerase chain reaction | |
dc.subject | priority journal | |
dc.subject | squamous cell carcinoma | |
dc.subject | wart virus | |
dc.subject | Adult | |
dc.subject | African Americans | |
dc.subject | African Continental Ancestry Group | |
dc.subject | Base Sequence | |
dc.subject | Carcinoma, Squamous Cell | |
dc.subject | DNA, Viral | |
dc.subject | Female | |
dc.subject | Humans | |
dc.subject | Male | |
dc.subject | Middle Aged | |
dc.subject | Molecular Sequence Data | |
dc.subject | Mouth Neoplasms | |
dc.subject | Papillomaviridae | |
dc.subject | South Africa | |
dc.title | Human papillomavirus DNA in oral squamous cell carcinomas from an African population sample | |
dc.type | Article |