Abruptio Placentae and Disseminated Intravascular Coagulopathy

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dc.contributor.authorHall D.R.
dc.date.accessioned2011-05-15T16:17:55Z
dc.date.available2011-05-15T16:17:55Z
dc.date.issued2009
dc.description.abstractAbruptio placentae is an important cause of vaginal bleeding in the latter half of pregnancy. The key factor in the pathophysiology is hemorrhage at the decidual-placental interface. Small episodes may escape clinical detection, but severe grades impact significantly on fetal and maternal morbidity and mortality, with the most frequent complications being fetal death, severe maternal shock, disseminated intravascular coagulopathy, and renal failure. Important risk factors for the development of abruptio placentae are previous abruption, hypertensive diseases, abdominal trauma, growth restriction, and smoking. The diagnosis is essentially made on the clinical picture that includes vaginal bleeding (usually dark blood), abdominal pain, and uterine contractions. The essence of management is restoration of circulating volume followed by delivery of the fetus and placenta, most often by cesarean section when the diagnosis is clear and the fetus alive and viable. Aggressive resuscitation and expeditious vaginal delivery are the goals when the fetus is dead. © 2009 Elsevier Inc. All rights reserved.
dc.description.versionReview
dc.identifier.citationSeminars in Perinatology
dc.identifier.citation33
dc.identifier.citation3
dc.identifier.issn01460005
dc.identifier.other10.1053/j.semperi.2009.02.005
dc.identifier.urihttp://hdl.handle.net/10019.1/14426
dc.subjectfibrinogen
dc.subjectfresh frozen plasma
dc.subjectrhesus D antibody
dc.subjectabdominal injury
dc.subjectabdominal pain
dc.subjectcesarean section
dc.subjectdisseminated intravascular clotting
dc.subjectfetal well being
dc.subjecthemorrhagic shock
dc.subjecthuman
dc.subjectintrauterine growth retardation
dc.subjectmaternal hypertension
dc.subjectmaternal morbidity
dc.subjectmaternal mortality
dc.subjectmaternal smoking
dc.subjectpathophysiology
dc.subjectpriority journal
dc.subjectresuscitation
dc.subjectreview
dc.subjectrhesus isoimmunization
dc.subjectrisk assessment
dc.subjectsolutio placentae
dc.subjecttocolysis
dc.subjectuterus contraction
dc.subjectvagina bleeding
dc.subjectvaginal delivery
dc.subjectAbruptio Placentae
dc.subjectDisseminated Intravascular Coagulation
dc.subjectFemale
dc.subjectHumans
dc.subjectPregnancy
dc.subjectRisk Factors
dc.subjectShock, Hemorrhagic
dc.titleAbruptio Placentae and Disseminated Intravascular Coagulopathy
dc.typeReview
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